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The map label for this gene is nikD [H]

Identifier: 238919641

GI number: 238919641

Start: 1694604

End: 1695401

Strand: Reverse

Name: nikD [H]

Synonym: NT01EI_1742

Alternate gene names: 238919641

Gene position: 1695401-1694604 (Counterclockwise)

Preceding gene: 238919642

Following gene: 238919640

Centisome position: 44.47

GC content: 65.16

Gene sequence:

>798_bases
ATGCTAAGTTTTCACAACATCACCCTGGAGGCAGCCCACTACCGCTGGTATGGCGCCCGTTGCTGGTCTCCCCTGCTACA
GGGAATAACCCTCGACGTCGCGCCCGGTGAGCTGGTAGCGCTGGTCGGCGGCAGCGGCGAAGGCAAGAGCCTGCTACTGC
AGTGTGCGCTCGATCTGCTGCCCGTGAATCTGCGCAGCCACGGCACGCTGAGTCTGGACGGAAAGCCACTCTCCGCCGAC
GGGCGCCGCCGCCTGCGCGGCCATACCCTGTGCTATGTCCCGCAGGGCGTCTCCGCGCTCAACCCACTGCTCAATATCGA
GCGACATCTGCAGCGTACCCGCCATCTGGCCGGTCAGCACTGGGATGCCGAGCAGGCCAGCGCGGTATTACGCCAAAGCC
ATCTCGATCCGACAACGGTGATGCACAGTTACCCGCGCCAGCTCTCCGGTGGTATGGCCAAGCGCGTGCTGGCTTGCCAT
GCCTCCCTCAGCCATGCCCGCTATATTCTGGCTGACGAAATCACCGCCTGGCTGGATGCGGCGCTGGCGCACCAGCTGCT
GCGCCAGCTGCGACACCTGTGTAAGCAAGGCTGCGGCATTCTGTGGGTCACCCACGATCTGATGCTGGCGGCACAGCACG
CCGATCGCATCGTCGCCCTGCACCAGGGCCAGGTCAGTGACAGCGTCAGCCGCGCGCAGCTGCAGCGCGGCGAAATCAGC
GAGCGACTCATGCGCCAGTGGCAGGCGCTGCCGGAGCGCGGCACCCTATTTTCTGATCTGGAGCGTGCCCCATGCTGA

Upstream 100 bases:

>100_bases
GGTGGCTGGTATTGTTTCCCGGCCTGATGCTGCTACTGCTGGTGCTGCTGTTCGATCAGTTTGCCCGCGCCCTGCAGCGA
CTGTGGCTAAGGAGTGAGTC

Downstream 100 bases:

>100_bases
TCTGCCGGGATTTAACGGTCCACCAGGGGGGAAAATATCTGTGGCAAGGTCTGAACCTCAACCTACGCCCGGGAGAGCGC
CTGGGGATCAGCGCGCCGAG

Product: ABC-type dipeptide/oligopeptide/nickel transporter, ATP-binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLSFHNITLEAAHYRWYGARCWSPLLQGITLDVAPGELVALVGGSGEGKSLLLQCALDLLPVNLRSHGTLSLDGKPLSAD
GRRRLRGHTLCYVPQGVSALNPLLNIERHLQRTRHLAGQHWDAEQASAVLRQSHLDPTTVMHSYPRQLSGGMAKRVLACH
ASLSHARYILADEITAWLDAALAHQLLRQLRHLCKQGCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQLQRGEIS
ERLMRQWQALPERGTLFSDLERAPC

Sequences:

>Translated_265_residues
MLSFHNITLEAAHYRWYGARCWSPLLQGITLDVAPGELVALVGGSGEGKSLLLQCALDLLPVNLRSHGTLSLDGKPLSAD
GRRRLRGHTLCYVPQGVSALNPLLNIERHLQRTRHLAGQHWDAEQASAVLRQSHLDPTTVMHSYPRQLSGGMAKRVLACH
ASLSHARYILADEITAWLDAALAHQLLRQLRHLCKQGCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQLQRGEIS
ERLMRQWQALPERGTLFSDLERAPC
>Mature_265_residues
MLSFHNITLEAAHYRWYGARCWSPLLQGITLDVAPGELVALVGGSGEGKSLLLQCALDLLPVNLRSHGTLSLDGKPLSAD
GRRRLRGHTLCYVPQGVSALNPLLNIERHLQRTRHLAGQHWDAEQASAVLRQSHLDPTTVMHSYPRQLSGGMAKRVLACH
ASLSHARYILADEITAWLDAALAHQLLRQLRHLCKQGCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQLQRGEIS
ERLMRQWQALPERGTLFSDLERAPC

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1789890, Length=229, Percent_Identity=33.1877729257642, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693107, Length=232, Percent_Identity=26.7241379310345, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787759, Length=218, Percent_Identity=30.7339449541284, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787029, Length=251, Percent_Identity=27.4900398406374, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789963, Length=210, Percent_Identity=31.4285714285714, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=31.2796208530806, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788506, Length=211, Percent_Identity=32.7014218009479, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789891, Length=235, Percent_Identity=28.936170212766, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787105, Length=206, Percent_Identity=32.5242718446602, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994883, Length=203, Percent_Identity=28.0788177339901, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789672, Length=260, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787548, Length=249, Percent_Identity=27.3092369477912, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081834, Length=226, Percent_Identity=30.5309734513274, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994997, Length=214, Percent_Identity=29.4392523364486, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=33.1730769230769, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=31.2217194570136, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787500, Length=222, Percent_Identity=25.2252252252252, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789032, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790544, Length=216, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=219, Percent_Identity=30.1369863013699, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=243, Percent_Identity=25.5144032921811, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17539902, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641565, Length=236, Percent_Identity=31.3559322033898, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015857
- InterPro:   IPR003593
- InterPro:   IPR014138 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 29412; Mature: 29412

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFHNITLEAAHYRWYGARCWSPLLQGITLDVAPGELVALVGGSGEGKSLLLQCALDLL
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
PVNLRSHGTLSLDGKPLSADGRRRLRGHTLCYVPQGVSALNPLLNIERHLQRTRHLAGQH
CCCCCCCCEEEECCCCCCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
WDAEQASAVLRQSHLDPTTVMHSYPRQLSGGMAKRVLACHASLSHARYILADEITAWLDA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAHQLLRQLRHLCKQGCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQLQRGEIS
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHH
ERLMRQWQALPERGTLFSDLERAPC
HHHHHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MLSFHNITLEAAHYRWYGARCWSPLLQGITLDVAPGELVALVGGSGEGKSLLLQCALDLL
CCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
PVNLRSHGTLSLDGKPLSADGRRRLRGHTLCYVPQGVSALNPLLNIERHLQRTRHLAGQH
CCCCCCCCEEEECCCCCCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
WDAEQASAVLRQSHLDPTTVMHSYPRQLSGGMAKRVLACHASLSHARYILADEITAWLDA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAHQLLRQLRHLCKQGCGILWVTHDLMLAAQHADRIVALHQGQVSDSVSRAQLQRGEIS
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHH
ERLMRQWQALPERGTLFSDLERAPC
HHHHHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]