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The map label for this gene is sohB [H]

Identifier: 238919608

GI number: 238919608

Start: 1663563

End: 1664609

Strand: Direct

Name: sohB [H]

Synonym: NT01EI_1707

Alternate gene names: 238919608

Gene position: 1663563-1664609 (Clockwise)

Preceding gene: 238919605

Following gene: 238919610

Centisome position: 43.64

GC content: 62.66

Gene sequence:

>1047_bases
GTGGAGTGGTTATCTTTATATAGCCTGTTTTTGGCCAAGGCGGCGACGCTGGTTGTGGTCGTAGCAGCGGTGGTATTACT
GGTGGTCGGACTGCGCCAGCGTCAGGGTAACAGCGGCGGAGAGCTGCTGCTGACGGACCTGGGCGAACAGTACCGAACCA
TGCAGCGCAGCATGCGCAGCGCCCGCCTGCAGGGGGCCGCGCTGAAGCAGTGGCGCCGTTTACAGAAGAAGGTGGCCAAG
GCAGAGGAGAAACAGCGTAAGTCAGAGGCGCGCGGCGGCCTGTTGGCGGCAGAGAAGCCCTGCGTCTATGTACTTGACTT
TACCGGCAGCATGGATGCCCGCGAGGTTGGCTCGCTGCGCGAGGAGATCAGCGCGGTACTGGCGGTTGCCGGTCCGCAGG
ATAGTGTACTGCTGCGCCTGGAAAGTCCGGGGGGCGTGGTGCACGGCTATGGCCTGGCTGCCTCGCAGTTAAAGCGTCTG
CGTCAGGCCGGGGTGCGCCTGACGGTGGCGGTCGATAAGGTAGCGGCCAGCGGCGGCTACATGATGGCCTGCGTCGCCGA
TCGTATTGTGGCGGCGCCGTTCGCCATTATCGGTTCCATTGGGGTTGTGGCCCAAATCCCCAATTTTAATCGCTGGCTGA
AGAAAAACGATGTCGACGTGGAGCTGCATACCGCCGGCGAGTTTAAGCGTACGCTGACGCTGTTTGGCGAGAATACCGAT
GTCGGCCGGGAAAAGTTCTGTCAGGAGCTGGATGAAACCCACCTGTTGTTCAAGCAGTTCGTGCAGCGTCAGCGCCCGTC
GCTGGACGTGGATAGCGTGGCGACCGGCGAGCACTGGTATGGCGAGCAGGCGCTGGAGAAGGGGCTGGTGGATGCGCTGA
GCACCAGTGACGATCTGTTGATCGCGGAGATGGAGCAGGCTGACGTGATCGGCGTGCGTTACGTGCGCCGTAAGGGACTC
ATGGCCCGGATGGGCATGGCGGCGGCGCAGGGAGCCGATATGCTGTTGCTGCGCTGGTGGCAACGCAGCCAGCGTCCGCT
CCCCTAA

Upstream 100 bases:

>100_bases
TGTGACATGGCCTTAGGCTGTCTGACGCAGGGCCATCGCCTCCGGAGATAAGGAGTCCTTGGCCGTTGGCATTAACATAA
CGAGCAACAAGGCGGTGAGT

Downstream 100 bases:

>100_bases
GGGAAACGTGAAGGGCGCGTGTTGGCGCGTCCTTCGCGGTATCCGATGCGTGCAGGGCGGCCAGAGTCAGCCAGCCAGGT
GGTATTTCTCTGACAATCTG

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEWLSLYSLFLAKAATLVVVVAAVVLLVVGLRQRQGNSGGELLLTDLGEQYRTMQRSMRSARLQGAALKQWRRLQKKVAK
AEEKQRKSEARGGLLAAEKPCVYVLDFTGSMDAREVGSLREEISAVLAVAGPQDSVLLRLESPGGVVHGYGLAASQLKRL
RQAGVRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFNRWLKKNDVDVELHTAGEFKRTLTLFGENTD
VGREKFCQELDETHLLFKQFVQRQRPSLDVDSVATGEHWYGEQALEKGLVDALSTSDDLLIAEMEQADVIGVRYVRRKGL
MARMGMAAAQGADMLLLRWWQRSQRPLP

Sequences:

>Translated_348_residues
MEWLSLYSLFLAKAATLVVVVAAVVLLVVGLRQRQGNSGGELLLTDLGEQYRTMQRSMRSARLQGAALKQWRRLQKKVAK
AEEKQRKSEARGGLLAAEKPCVYVLDFTGSMDAREVGSLREEISAVLAVAGPQDSVLLRLESPGGVVHGYGLAASQLKRL
RQAGVRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFNRWLKKNDVDVELHTAGEFKRTLTLFGENTD
VGREKFCQELDETHLLFKQFVQRQRPSLDVDSVATGEHWYGEQALEKGLVDALSTSDDLLIAEMEQADVIGVRYVRRKGL
MARMGMAAAQGADMLLLRWWQRSQRPLP
>Mature_348_residues
MEWLSLYSLFLAKAATLVVVVAAVVLLVVGLRQRQGNSGGELLLTDLGEQYRTMQRSMRSARLQGAALKQWRRLQKKVAK
AEEKQRKSEARGGLLAAEKPCVYVLDFTGSMDAREVGSLREEISAVLAVAGPQDSVLLRLESPGGVVHGYGLAASQLKRL
RQAGVRLTVAVDKVAASGGYMMACVADRIVAAPFAIIGSIGVVAQIPNFNRWLKKNDVDVELHTAGEFKRTLTLFGENTD
VGREKFCQELDETHLLFKQFVQRQRPSLDVDSVATGEHWYGEQALEKGLVDALSTSDDLLIAEMEQADVIGVRYVRRKGL
MARMGMAAAQGADMLLLRWWQRSQRPLP

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=348, Percent_Identity=61.7816091954023, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1788064, Length=189, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38337; Mature: 38337

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLSLYSLFLAKAATLVVVVAAVVLLVVGLRQRQGNSGGELLLTDLGEQYRTMQRSMRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
ARLQGAALKQWRRLQKKVAKAEEKQRKSEARGGLLAAEKPCVYVLDFTGSMDAREVGSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCHHHHHHHH
EEISAVLAVAGPQDSVLLRLESPGGVVHGYGLAASQLKRLRQAGVRLTVAVDKVAASGGY
HHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEEEEHHHCCCCC
MMACVADRIVAAPFAIIGSIGVVAQIPNFNRWLKKNDVDVELHTAGEFKRTLTLFGENTD
HHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHCCCCCEEEECCCCHHHEEEEECCCCC
VGREKFCQELDETHLLFKQFVQRQRPSLDVDSVATGEHWYGEQALEKGLVDALSTSDDLL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
IAEMEQADVIGVRYVRRKGLMARMGMAAAQGADMLLLRWWQRSQRPLP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEWLSLYSLFLAKAATLVVVVAAVVLLVVGLRQRQGNSGGELLLTDLGEQYRTMQRSMRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
ARLQGAALKQWRRLQKKVAKAEEKQRKSEARGGLLAAEKPCVYVLDFTGSMDAREVGSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCHHHHHHHH
EEISAVLAVAGPQDSVLLRLESPGGVVHGYGLAASQLKRLRQAGVRLTVAVDKVAASGGY
HHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHCCCEEEEEEEHHHCCCCC
MMACVADRIVAAPFAIIGSIGVVAQIPNFNRWLKKNDVDVELHTAGEFKRTLTLFGENTD
HHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHCCCCCEEEECCCCHHHEEEEECCCCC
VGREKFCQELDETHLLFKQFVQRQRPSLDVDSVATGEHWYGEQALEKGLVDALSTSDDLL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
IAEMEQADVIGVRYVRRKGLMARMGMAAAQGADMLLLRWWQRSQRPLP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]