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The map label for this gene is fadR

Identifier: 238919534

GI number: 238919534

Start: 1590379

End: 1591098

Strand: Direct

Name: fadR

Synonym: NT01EI_1630

Alternate gene names: 238919534

Gene position: 1590379-1591098 (Clockwise)

Preceding gene: 238919531

Following gene: 238919536

Centisome position: 41.72

GC content: 56.53

Gene sequence:

>720_bases
ATGGTTATTAAGGCGCAGAGTCCAGCTGGTTTTGCGGAAGAGTATTTGATTGAAAGTATTTGGAATAACCGTTTCCCTCC
CGGTTCTATCCTGCCCGCAGAGCGTGAGTTGTCTGAGCTGATTGGCGTTACCCGAACTACCCTGCGTGAGGTGCTGCAGC
GTTTAGCGCGCGATGGATGGCTGACCATCCGGCATGGTAAGCCGACGCAGGTGAACAACTTTTGGGAAACCTCCGGGCTG
AATATTCTGGAGACGCTGGCACGTTTGGATCACGATAGCGTCCCGCAGCTAATCGATAATGTGCTGGCCGTACGTACCAA
TATTGCCGCTATCTTCATTCGCGCCGCGGTGCGTCAGCACCCGGACAGGGTTCAGGCTATTGTAGCCGATGCCCCGACGG
TGGAGGATAGCGCCGATGCTTTTGCCGACTTGGACTATCGTATTTTTCGCGCCTTGGCCTTTGCCTGCGGCAATCCGATC
TATGGCCTGATCCTCAATGGATTGAAGGGTCTGTATACCCGGGTCGGTCGCTACTACTTTTCCAATCCACAGGCACGCCG
TCTGGCACTGGCGTTTTATTCGCGTCTCGGCGAGCTGGCAGCCTCCCGCCAGTATGACCGGGTGATGGATTTTGTCCGCA
GCTACGGTAAAGAGAGCGGCGCCATCTGGCATGGAATGCAGAGCGGGATCCCGCGCGACTTGGCCGATGGGCACGCCTGA

Upstream 100 bases:

>100_bases
TATGTAAGCGCCATCGGCGCTATATCAACGGGTTGCCATCTGGTATGATGAGCAACCTTGTTTTTGCTTATTCTTATTGT
CGTGACGGAACGTTAACAAC

Downstream 100 bases:

>100_bases
TCAGGCGGAGCATTCATCAGATCTCCGTTAACCGGGGGCGCCTGGCCCCCCCGGTCTTTACTTAGATCCCGTCAGGATGC
GGTGGGCATCGCTCCAGCAG

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MVIKAQSPAGFAEEYLIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIRHGKPTQVNNFWETSGL
NILETLARLDHDSVPQLIDNVLAVRTNIAAIFIRAAVRQHPDRVQAIVADAPTVEDSADAFADLDYRIFRALAFACGNPI
YGLILNGLKGLYTRVGRYYFSNPQARRLALAFYSRLGELAASRQYDRVMDFVRSYGKESGAIWHGMQSGIPRDLADGHA

Sequences:

>Translated_239_residues
MVIKAQSPAGFAEEYLIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIRHGKPTQVNNFWETSGL
NILETLARLDHDSVPQLIDNVLAVRTNIAAIFIRAAVRQHPDRVQAIVADAPTVEDSADAFADLDYRIFRALAFACGNPI
YGLILNGLKGLYTRVGRYYFSNPQARRLALAFYSRLGELAASRQYDRVMDFVRSYGKESGAIWHGMQSGIPRDLADGHA
>Mature_239_residues
MVIKAQSPAGFAEEYLIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIRHGKPTQVNNFWETSGL
NILETLARLDHDSVPQLIDNVLAVRTNIAAIFIRAAVRQHPDRVQAIVADAPTVEDSADAFADLDYRIFRALAFACGNPI
YGLILNGLKGLYTRVGRYYFSNPQARRLALAFYSRLGELAASRQYDRVMDFVRSYGKESGAIWHGMQSGIPRDLADGHA

Specific function: Multifunctional regulator of fatty acid metabolism

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787436, Length=235, Percent_Identity=77.0212765957447, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FADR_EDWI9 (C5B9W3)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933049.1
- ProteinModelPortal:   C5B9W3
- GeneID:   7961958
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1630
- OMA:   IVRSIWE
- ProtClustDB:   PRK04984
- GO:   GO:0005737
- HAMAP:   MF_00696
- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345
- TIGRFAMs:   TIGR02812

Pfam domain/function: PF07840 FadR_C; PF00392 GntR; SSF48008 FadR_C

EC number: NA

Molecular weight: Translated: 26758; Mature: 26758

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKAQSPAGFAEEYLIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIRHGKPTQVNNFWETSGLNILETLARLDHDSVPQLIDNVLAVRTNIAAIFIRAAVRQH
EEEECCCCCCCCCCHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDRVQAIVADAPTVEDSADAFADLDYRIFRALAFACGNPIYGLILNGLKGLYTRVGRYYF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SNPQARRLALAFYSRLGELAASRQYDRVMDFVRSYGKESGAIWHGMQSGIPRDLADGHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVIKAQSPAGFAEEYLIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIRHGKPTQVNNFWETSGLNILETLARLDHDSVPQLIDNVLAVRTNIAAIFIRAAVRQH
EEEECCCCCCCCCCHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDRVQAIVADAPTVEDSADAFADLDYRIFRALAFACGNPIYGLILNGLKGLYTRVGRYYF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SNPQARRLALAFYSRLGELAASRQYDRVMDFVRSYGKESGAIWHGMQSGIPRDLADGHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA