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The map label for this gene is ruvC

Identifier: 238919501

GI number: 238919501

Start: 1558844

End: 1559365

Strand: Direct

Name: ruvC

Synonym: NT01EI_1597

Alternate gene names: 238919501

Gene position: 1558844-1559365 (Clockwise)

Preceding gene: 238919500

Following gene: 238919502

Centisome position: 40.89

GC content: 64.18

Gene sequence:

>522_bases
ATGAGTATCATCCTCGGGATTGACCCCGGCTCGCGGATCACCGGCTATGGCGTGATCCGCCAGCAGGGGAGGCAGCTCGA
ATATATCGGCAGCGGCTGCATCCGCACTGCCGTCGACGATCTGCCTACCCGTCTTAAGCTGGTGTACGCCGGCGTCAGTG
AAATCATCACCCAGTTCAACCCCGACTGCTTCGCCATTGAACAGGTTTTTATGGCCAAGAACGCCGATTCGGCGCTGAAG
CTGGGACAGGCGCGCGGCGCCGCCATCGTGGCGGCGGTGAACCGTGATCTGCCGGTGTTTGAATACGCGGCGCGCCAGAT
CAAGCAGACGGTGGTGGGCAACGGCGGGGCGGAAAAGGCCCAGGTGCAGCATATGGTGCGCTCGCTGCTGAAGCTGCCGG
CGAACCCACAGGCGGACGCCGCCGATGCGTTGGCCGTGGCGATCACCCACTGCCACGTCAGCCAGAACGCGCTGCGCATC
AGCAGCGGCAGGCTGAATCTGGCACGGGGACGCTTGCGCTGA

Upstream 100 bases:

>100_bases
CGAAGCTGCTGCGTCTGATCGATATGCTGGAAGACTGCGATGATGTGCAGGAAGTGTATCACAATGGTGAAATCTCCGAT
GAGGTTGCGGCTACTCTGGA

Downstream 100 bases:

>100_bases
CCGCGGCGTGCGAAATGTGCGCTGTGCGGAGAGGGCGGGAGATGCCCGACGCTTTATTACAGGCTGGATATTCATCCAGC
CTTTTTTATGGTATAAGCGG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSIILGIDPGSRITGYGVIRQQGRQLEYIGSGCIRTAVDDLPTRLKLVYAGVSEIITQFNPDCFAIEQVFMAKNADSALK
LGQARGAAIVAAVNRDLPVFEYAARQIKQTVVGNGGAEKAQVQHMVRSLLKLPANPQADAADALAVAITHCHVSQNALRI
SSGRLNLARGRLR

Sequences:

>Translated_173_residues
MSIILGIDPGSRITGYGVIRQQGRQLEYIGSGCIRTAVDDLPTRLKLVYAGVSEIITQFNPDCFAIEQVFMAKNADSALK
LGQARGAAIVAAVNRDLPVFEYAARQIKQTVVGNGGAEKAQVQHMVRSLLKLPANPQADAADALAVAITHCHVSQNALRI
SSGRLNLARGRLR
>Mature_172_residues
SIILGIDPGSRITGYGVIRQQGRQLEYIGSGCIRTAVDDLPTRLKLVYAGVSEIITQFNPDCFAIEQVFMAKNADSALKL
GQARGAAIVAAVNRDLPVFEYAARQIKQTVVGNGGAEKAQVQHMVRSLLKLPANPQADAADALAVAITHCHVSQNALRIS
SGRLNLARGRLR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=173, Percent_Identity=85.5491329479769, Blast_Score=290, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_EDWI9 (C5B9T0)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933016.1
- GeneID:   7961925
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1597
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18550; Mature: 18419

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILGIDPGSRITGYGVIRQQGRQLEYIGSGCIRTAVDDLPTRLKLVYAGVSEIITQFN
CEEEEECCCCCCEEHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDCFAIEQVFMAKNADSALKLGQARGAAIVAAVNRDLPVFEYAARQIKQTVVGNGGAEKA
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHH
QVQHMVRSLLKLPANPQADAADALAVAITHCHVSQNALRISSGRLNLARGRLR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCC
>Mature Secondary Structure 
SIILGIDPGSRITGYGVIRQQGRQLEYIGSGCIRTAVDDLPTRLKLVYAGVSEIITQFN
EEEEECCCCCCEEHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDCFAIEQVFMAKNADSALKLGQARGAAIVAAVNRDLPVFEYAARQIKQTVVGNGGAEKA
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHH
QVQHMVRSLLKLPANPQADAADALAVAITHCHVSQNALRISSGRLNLARGRLR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA