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The map label for this gene is cutC

Identifier: 238919491

GI number: 238919491

Start: 1549690

End: 1550445

Strand: Direct

Name: cutC

Synonym: NT01EI_1587

Alternate gene names: 238919491

Gene position: 1549690-1550445 (Clockwise)

Preceding gene: 238919489

Following gene: 238919494

Centisome position: 40.65

GC content: 63.23

Gene sequence:

>756_bases
ATGCTGACGTTAGAGGTATGCTGCTACTCCCTGGCCTGCGCCGAGATAGCGCAGGCGGCGGGGGCAGACCGCATTGAGCT
GTGTGCCAGCCAGCAGGATGGTGGGATCACCCCCAGCTATGGCACGCTGGTGGGGTGTCGGGAGCGGGTGAGCGTGCCTG
TACACCCGATTATCCGTCCGCGCAGCGGCGATTTTTGCTACAGCGACAGCGAGTTTGCGCTGATGAAGTGCGATCTGGCG
CTGGTGCGCGATCTGGGGTTTCCCGGCGCGGTGATCGGCTTACTGGATGAAGAGGGACACATTGATCTGCGCCGCATGGG
TGAGCTGATGGCGTTGGCCGGTCCGATGGCGGTGACCTTTCACCGCGCCTTCGACATGTGCGCCAACCCGCTGCAGGCGC
TTTCCCAGCTGACCGATCTCGGTATTGCGCGCATTCTGACCTCAGGGCAGCAGCAGACGGCGGAGGCCGGGTTGCCGCTG
CTGCGTCAGCTGCAGCAGGCCAGCCGCGGACCGCTGATCATGGCCGGGGCCGGGGTGCGCCTCTCCAATCTGCATAAATT
CAGTGGGATTGGTCTGCAGGAGGTGCATACCTCTGCCGGCCACTGTGTGCCGTCAACGATGCGCTACCGCAAGGCGGGCG
TCAGCATGAGCCATGCGGAGAACGATGAGTTTAGCCACTACTGCGTGGACGGCGGTATGGTTGAGGCGATGAAATCGGCG
CTGCAGATGATGGAAACCGTCGGCTGCAGCATCTGA

Upstream 100 bases:

>100_bases
TACAGAGTAGGCGAGGTGAGGGGAGATTCTCAATATTTGGGCTGTTGATATGAGTATTTTTCACATCCGCACCGTTTTGG
CTGTTGATTCGGAGGTTTAT

Downstream 100 bases:

>100_bases
GGAACCGGTCTCCAGTAGACGTAAGTACGGCTTTGTAGCGGAGGGTTTGCTAAAAAGTTCGGCCCCACACCTTGCCGGTT
GGGGCTCTTTTTTATGGCGC

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRPRSGDFCYSDSEFALMKCDLA
LVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTFHRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPL
LRQLQQASRGPLIMAGAGVRLSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSA
LQMMETVGCSI

Sequences:

>Translated_251_residues
MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRPRSGDFCYSDSEFALMKCDLA
LVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTFHRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPL
LRQLQQASRGPLIMAGAGVRLSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSA
LQMMETVGCSI
>Mature_251_residues
MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRPRSGDFCYSDSEFALMKCDLA
LVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTFHRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPL
LRQLQQASRGPLIMAGAGVRLSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSA
LQMMETVGCSI

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=239, Percent_Identity=41.8410041841004, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI87081995, Length=243, Percent_Identity=57.6131687242798, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17556905, Length=185, Percent_Identity=36.2162162162162, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355415, Length=256, Percent_Identity=33.984375, Blast_Score=131, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_EDWI9 (C5B835)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933006.1
- ProteinModelPortal:   C5B835
- GeneID:   7961915
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1587
- OMA:   PVYAMIR
- ProtClustDB:   PRK11572
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 26849; Mature: 26849

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRP
CCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
RSGDFCYSDSEFALMKCDLALVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTF
CCCCCCCCCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHH
HRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPLLRQLQQASRGPLIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCEEEECCCCC
LSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSA
HHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHH
LQMMETVGCSI
HHHHHHHCCCC
>Mature Secondary Structure
MLTLEVCCYSLACAEIAQAAGADRIELCASQQDGGITPSYGTLVGCRERVSVPVHPIIRP
CCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
RSGDFCYSDSEFALMKCDLALVRDLGFPGAVIGLLDEEGHIDLRRMGELMALAGPMAVTF
CCCCCCCCCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHH
HRAFDMCANPLQALSQLTDLGIARILTSGQQQTAEAGLPLLRQLQQASRGPLIMAGAGVR
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCEEEECCCCC
LSNLHKFSGIGLQEVHTSAGHCVPSTMRYRKAGVSMSHAENDEFSHYCVDGGMVEAMKSA
HHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHH
LQMMETVGCSI
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA