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The map label for this gene is dcuD [H]

Identifier: 238919382

GI number: 238919382

Start: 1449734

End: 1451203

Strand: Reverse

Name: dcuD [H]

Synonym: NT01EI_1476

Alternate gene names: 238919382

Gene position: 1451203-1449734 (Counterclockwise)

Preceding gene: 238919383

Following gene: 238919380

Centisome position: 38.07

GC content: 61.63

Gene sequence:

>1470_bases
ATGAGCCTACTGATCGCGCTGTGCGCCGTGCTGTTTGCCGGGCGCCTGATCCTGAAAAACTATAATCCCCAGGCAGTATT
GCTGCTGAGCGGCCTGGTGATGATGGCCATCGCCGTCTTTACCAACGACGCCACCTTTATCAACAAGTCGACCGGCTGGA
TCGGTTTTGACCTGTTGGAGTACATCAACCAGCTGTTCCAGAAGATGGGCGGCGGCCTTGGGCTGCAGATCATGCTGATC
GGCGGCTTTGCCATGTATATGTCCGCCATCGGCGCCAGCCAGGCGCTGGTGCGGGTGACCGCGCGCCCGCTACAGCGCCT
TAACTCCCCCTACCTGCTGCTGGGGATCGCCTTTATCCTCGGCCAGACGCTGTCGCTGTTTATCACCAGCGCCACCGGGT
TGAGCCTGCTGTTGATGGCGACCCTGTATCCGGTTCTGACCCGCCTGGGCTGTAGCCGTGCGGCGGCGGCGGCGGTGCTG
GCCAGTACCTGCGCCATCGAGTTCGGCCCCGGATCCGGTAACTCCATCATGGCGTCGCAGACCTCGGGCATGGATATCAC
CGAATACTTCATCCACCAGCAGCTGCCGGTCGCCGTGCTGACCATCCTGGTGGTGGCACTGCTGCATATCCTGGTGCAAC
GCTACTTTGATCGCCGCGATGGCGCCATGGCTGAAGAGGTGAGTCTGGATCAGGAGAAGCTGCAGGAGACCCAGAGCGAT
GCGCCGCTGCACTATGTGCTGCTGCCGATGCTGCCGCTGTTCTTCATGCTGACCTTCAGCAAGCTGGGCGTCGGTACCAT
CGTCATCAACATGAATACCGCCGTGCTGATCAGCGTCGCGCTCTCCATGCTGTGCGAATACCTGCGCTTCCGCGCCGCCA
AGCCGGTGATGGCCGGGCTCAGCGTGGTCTTCAGCAATATGGGGAAGGTGTTCGCTACCGTAGTGACGCTGATCGTCGCC
GGTCAGACCTTTGCCGAGGGGCTAAAGTCGATTGGTGCGGTGCATGATCTGCTGGATCTGGCCAGCAATGCCGGCTTTGG
CAGCGGCGTGGTGGTCCTGCTGATGGCGCTGTTAACCTTCACCATCGCCGCCCTGATGGGCTCCGGCAACGCCGCCTTCT
TCTCTTTTGCACCGATGCTGCCGGATATCGCCAAGCGCGTCGGCGGCAGTACGGCCGAGATGATCCTGCCGGTGCAGATC
TCCGCCGGTATGGGACGCACCATCTCGCCGATCGCCGGGGTGATCATCGCCGTCGCCGGTATCGCCGGCATCTCGCAGGT
TGATATCGTACGCCGCACCCTGATCCCGATGCTCGGCGGCTGGTGCTTTATGCTGCTGCTGACCTTCTACCGCTCCGGTC
AGCTGCTGTCGGTACTGCCCTTTATCGCGCTGCTGATGGTGATCATGGCCGGTGGCGTATACGCCATGGCGCGTAAAAAA
CGTGATGCGGTGCAGAGCAACGCCGCTTAA

Upstream 100 bases:

>100_bases
GATAATCTGCGCCCCGAACGCGTATACGCCCGCGGCCGCCTGATGCTGAAGGGAGAGGAGTGTCTGGCCATGGGTAACTT
TGAACAAGGAAACTGAGATA

Downstream 100 bases:

>100_bases
ACAGCGTATCCCCCGCCGGGGTTATCCACGCGGCACCTGCCATCGCAGGGGCCGCGTTCTCCCCCGCTGACCCCGGCCTC
CCCTATCCTGCGCCCCGTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSLLIALCAVLFAGRLILKNYNPQAVLLLSGLVMMAIAVFTNDATFINKSTGWIGFDLLEYINQLFQKMGGGLGLQIMLI
GGFAMYMSAIGASQALVRVTARPLQRLNSPYLLLGIAFILGQTLSLFITSATGLSLLLMATLYPVLTRLGCSRAAAAAVL
ASTCAIEFGPGSGNSIMASQTSGMDITEYFIHQQLPVAVLTILVVALLHILVQRYFDRRDGAMAEEVSLDQEKLQETQSD
APLHYVLLPMLPLFFMLTFSKLGVGTIVINMNTAVLISVALSMLCEYLRFRAAKPVMAGLSVVFSNMGKVFATVVTLIVA
GQTFAEGLKSIGAVHDLLDLASNAGFGSGVVVLLMALLTFTIAALMGSGNAAFFSFAPMLPDIAKRVGGSTAEMILPVQI
SAGMGRTISPIAGVIIAVAGIAGISQVDIVRRTLIPMLGGWCFMLLLTFYRSGQLLSVLPFIALLMVIMAGGVYAMARKK
RDAVQSNAA

Sequences:

>Translated_489_residues
MSLLIALCAVLFAGRLILKNYNPQAVLLLSGLVMMAIAVFTNDATFINKSTGWIGFDLLEYINQLFQKMGGGLGLQIMLI
GGFAMYMSAIGASQALVRVTARPLQRLNSPYLLLGIAFILGQTLSLFITSATGLSLLLMATLYPVLTRLGCSRAAAAAVL
ASTCAIEFGPGSGNSIMASQTSGMDITEYFIHQQLPVAVLTILVVALLHILVQRYFDRRDGAMAEEVSLDQEKLQETQSD
APLHYVLLPMLPLFFMLTFSKLGVGTIVINMNTAVLISVALSMLCEYLRFRAAKPVMAGLSVVFSNMGKVFATVVTLIVA
GQTFAEGLKSIGAVHDLLDLASNAGFGSGVVVLLMALLTFTIAALMGSGNAAFFSFAPMLPDIAKRVGGSTAEMILPVQI
SAGMGRTISPIAGVIIAVAGIAGISQVDIVRRTLIPMLGGWCFMLLLTFYRSGQLLSVLPFIALLMVIMAGGVYAMARKK
RDAVQSNAA
>Mature_488_residues
SLLIALCAVLFAGRLILKNYNPQAVLLLSGLVMMAIAVFTNDATFINKSTGWIGFDLLEYINQLFQKMGGGLGLQIMLIG
GFAMYMSAIGASQALVRVTARPLQRLNSPYLLLGIAFILGQTLSLFITSATGLSLLLMATLYPVLTRLGCSRAAAAAVLA
STCAIEFGPGSGNSIMASQTSGMDITEYFIHQQLPVAVLTILVVALLHILVQRYFDRRDGAMAEEVSLDQEKLQETQSDA
PLHYVLLPMLPLFFMLTFSKLGVGTIVINMNTAVLISVALSMLCEYLRFRAAKPVMAGLSVVFSNMGKVFATVVTLIVAG
QTFAEGLKSIGAVHDLLDLASNAGFGSGVVVLLMALLTFTIAALMGSGNAAFFSFAPMLPDIAKRVGGSTAEMILPVQIS
AGMGRTISPIAGVIIAVAGIAGISQVDIVRRTLIPMLGGWCFMLLLTFYRSGQLLSVLPFIALLMVIMAGGVYAMARKKR
DAVQSNAA

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=456, Percent_Identity=39.0350877192982, Blast_Score=321, Evalue=7e-89,
Organism=Escherichia coli, GI1786839, Length=388, Percent_Identity=38.659793814433, Blast_Score=234, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 51917; Mature: 51786

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLIALCAVLFAGRLILKNYNPQAVLLLSGLVMMAIAVFTNDATFINKSTGWIGFDLLE
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHH
YINQLFQKMGGGLGLQIMLIGGFAMYMSAIGASQALVRVTARPLQRLNSPYLLLGIAFIL
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GQTLSLFITSATGLSLLLMATLYPVLTRLGCSRAAAAAVLASTCAIEFGPGSGNSIMASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCEEECC
TSGMDITEYFIHQQLPVAVLTILVVALLHILVQRYFDRRDGAMAEEVSLDQEKLQETQSD
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCC
APLHYVLLPMLPLFFMLTFSKLGVGTIVINMNTAVLISVALSMLCEYLRFRAAKPVMAGL
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SVVFSNMGKVFATVVTLIVAGQTFAEGLKSIGAVHDLLDLASNAGFGSGVVVLLMALLTF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TIAALMGSGNAAFFSFAPMLPDIAKRVGGSTAEMILPVQISAGMGRTISPIAGVIIAVAG
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHH
IAGISQVDIVRRTLIPMLGGWCFMLLLTFYRSGQLLSVLPFIALLMVIMAGGVYAMARKK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RDAVQSNAA
HHHHHCCCC
>Mature Secondary Structure 
SLLIALCAVLFAGRLILKNYNPQAVLLLSGLVMMAIAVFTNDATFINKSTGWIGFDLLE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHH
YINQLFQKMGGGLGLQIMLIGGFAMYMSAIGASQALVRVTARPLQRLNSPYLLLGIAFIL
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GQTLSLFITSATGLSLLLMATLYPVLTRLGCSRAAAAAVLASTCAIEFGPGSGNSIMASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCEEECC
TSGMDITEYFIHQQLPVAVLTILVVALLHILVQRYFDRRDGAMAEEVSLDQEKLQETQSD
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCC
APLHYVLLPMLPLFFMLTFSKLGVGTIVINMNTAVLISVALSMLCEYLRFRAAKPVMAGL
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SVVFSNMGKVFATVVTLIVAGQTFAEGLKSIGAVHDLLDLASNAGFGSGVVVLLMALLTF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TIAALMGSGNAAFFSFAPMLPDIAKRVGGSTAEMILPVQISAGMGRTISPIAGVIIAVAG
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHH
IAGISQVDIVRRTLIPMLGGWCFMLLLTFYRSGQLLSVLPFIALLMVIMAGGVYAMARKK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RDAVQSNAA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]