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The map label for this gene is yngG [H]

Identifier: 238919278

GI number: 238919278

Start: 1357174

End: 1358085

Strand: Direct

Name: yngG [H]

Synonym: NT01EI_1368

Alternate gene names: 238919278

Gene position: 1357174-1358085 (Clockwise)

Preceding gene: 238919277

Following gene: 238919279

Centisome position: 35.6

GC content: 60.42

Gene sequence:

>912_bases
ATGACAGAGCAGACCCGCGTAAATATTGTGGAGATCGGCCCGCGTGACGGGTTCCAAAACGTGCGCGATTTTATTCCCAC
TGCGCTGAAAATCGAGATTATTGAGGGGATCATCAGCGCGGGGGTACAGCGTATGCAGCTTACCTCGTTCGTTAGCCCGG
CGGCCATCGCCCAGATGCGTGATGCCGAGATCATCAGCCGCCACTGTATTCCACGCTATCCCGATCGCCAGTTCTCCGCG
CTGGTGCCCAATTTTCACGGCGCCCGGCTGGCGCAGGCGTGCGGTTATCGCGAGATAACCCCGGTGATCTCGCTCAGCGA
GACCCATAACCTGAAAAACGTGAATAAAACGCACCGCCAGTCGCTGGATGAGATCGCCCGCATTCGCCAGAGCTTTCCCG
AGGTACACATTGTGCAGGATATCGCGACTGTCTTTGGCTGCCCTTACGAGGGGCGGATGGCCACGCCGCCGCTGCTGGCG
CTGATTACGGCCCTGACGGCCGAGGGGATCGATGAGTTTACGCTGTGCGACACCATCGGCGTGGCCTACCCTGAGCAGGT
GCTGTCGACCCTGAACGCAGTGCGCTCGGCTTTTCCGGCGGTGAAGCTCAATATCCACATTCATGACACGCGCAACATGG
GCATCATCAACAGCTATCTGGCGGCGGCCTGGCCGGTCGATGCCATCCAGACGTCGCTGGGGGGATTGGGCGGCTGCCCC
TTTGCGCCGGGCGCCTCCGGCAATACGGCCACGGAGGATCTGGTTTACCTGCTGCATGCGCAGGGGATGGCGACCGGGAT
CGATTTTTCCCGCCTGCTGGCCACGGCGAAACATCTGCATCAGCATGTCGGGGGCAGCTACAGCGGCCACCATTTACACA
TCAGCGCCCGCCAGAAAGATTTTAACCCTTAG

Upstream 100 bases:

>100_bases
AGGCGCTGATGGCCCGCTATGGGCTGGATGCCGCACATATCGTCGCCGCCGCCCAGCGGGCGCTGGCACTCAAGGGCGGC
CAATAAAAGGAGAAGTGGTA

Downstream 100 bases:

>100_bases
AGCCAAAGGAGTGACCAGATGGAACAAACGTTAGCGGGCATCGTGGTGCTGGATCTGACCCGCGTACTGGCCGGGCCGTT
TTGCAGCATGCTGCTGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTEQTRVNIVEIGPRDGFQNVRDFIPTALKIEIIEGIISAGVQRMQLTSFVSPAAIAQMRDAEIISRHCIPRYPDRQFSA
LVPNFHGARLAQACGYREITPVISLSETHNLKNVNKTHRQSLDEIARIRQSFPEVHIVQDIATVFGCPYEGRMATPPLLA
LITALTAEGIDEFTLCDTIGVAYPEQVLSTLNAVRSAFPAVKLNIHIHDTRNMGIINSYLAAAWPVDAIQTSLGGLGGCP
FAPGASGNTATEDLVYLLHAQGMATGIDFSRLLATAKHLHQHVGGSYSGHHLHISARQKDFNP

Sequences:

>Translated_303_residues
MTEQTRVNIVEIGPRDGFQNVRDFIPTALKIEIIEGIISAGVQRMQLTSFVSPAAIAQMRDAEIISRHCIPRYPDRQFSA
LVPNFHGARLAQACGYREITPVISLSETHNLKNVNKTHRQSLDEIARIRQSFPEVHIVQDIATVFGCPYEGRMATPPLLA
LITALTAEGIDEFTLCDTIGVAYPEQVLSTLNAVRSAFPAVKLNIHIHDTRNMGIINSYLAAAWPVDAIQTSLGGLGGCP
FAPGASGNTATEDLVYLLHAQGMATGIDFSRLLATAKHLHQHVGGSYSGHHLHISARQKDFNP
>Mature_302_residues
TEQTRVNIVEIGPRDGFQNVRDFIPTALKIEIIEGIISAGVQRMQLTSFVSPAAIAQMRDAEIISRHCIPRYPDRQFSAL
VPNFHGARLAQACGYREITPVISLSETHNLKNVNKTHRQSLDEIARIRQSFPEVHIVQDIATVFGCPYEGRMATPPLLAL
ITALTAEGIDEFTLCDTIGVAYPEQVLSTLNAVRSAFPAVKLNIHIHDTRNMGIINSYLAAAWPVDAIQTSLGGLGGCPF
APGASGNTATEDLVYLLHAQGMATGIDFSRLLATAKHLHQHVGGSYSGHHLHISARQKDFNP

Specific function: Involved in the catabolism of branched amino acids such as leucine (Probable) [H]

COG id: COG0119

COG function: function code E; Isopropylmalate/homocitrate/citramalate synthases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMG-CoA lyase family [H]

Homologues:

Organism=Homo sapiens, GI62198232, Length=280, Percent_Identity=36.4285714285714, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI109150427, Length=279, Percent_Identity=34.0501792114695, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI109150422, Length=279, Percent_Identity=34.0501792114695, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI260654708, Length=280, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510563, Length=287, Percent_Identity=35.191637630662, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24582381, Length=282, Percent_Identity=35.8156028368794, Blast_Score=187, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like [H]

EC number: =4.1.3.4 [H]

Molecular weight: Translated: 33063; Mature: 32932

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTRVNIVEIGPRDGFQNVRDFIPTALKIEIIEGIISAGVQRMQLTSFVSPAAIAQMR
CCCCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DAEIISRHCIPRYPDRQFSALVPNFHGARLAQACGYREITPVISLSETHNLKNVNKTHRQ
HHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCHHEECHHHCCCCCCCHHHHH
SLDEIARIRQSFPEVHIVQDIATVFGCPYEGRMATPPLLALITALTAEGIDEFTLCDTIG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHC
VAYPEQVLSTLNAVRSAFPAVKLNIHIHDTRNMGIINSYLAAAWPVDAIQTSLGGLGGCP
CCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCC
FAPGASGNTATEDLVYLLHAQGMATGIDFSRLLATAKHLHQHVGGSYSGHHLHISARQKD
CCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
FNP
CCC
>Mature Secondary Structure 
TEQTRVNIVEIGPRDGFQNVRDFIPTALKIEIIEGIISAGVQRMQLTSFVSPAAIAQMR
CCCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DAEIISRHCIPRYPDRQFSALVPNFHGARLAQACGYREITPVISLSETHNLKNVNKTHRQ
HHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCHHEECHHHCCCCCCCHHHHH
SLDEIARIRQSFPEVHIVQDIATVFGCPYEGRMATPPLLALITALTAEGIDEFTLCDTIG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHC
VAYPEQVLSTLNAVRSAFPAVKLNIHIHDTRNMGIINSYLAAAWPVDAIQTSLGGLGGCP
CCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCC
FAPGASGNTATEDLVYLLHAQGMATGIDFSRLLATAKHLHQHVGGSYSGHHLHISARQKD
CCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
FNP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]