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The map label for this gene is tktB [C]

Identifier: 238919276

GI number: 238919276

Start: 1355374

End: 1356222

Strand: Direct

Name: tktB [C]

Synonym: NT01EI_1366

Alternate gene names: 238919276

Gene position: 1355374-1356222 (Clockwise)

Preceding gene: 238919275

Following gene: 238919277

Centisome position: 35.55

GC content: 64.55

Gene sequence:

>849_bases
ATGGATATCACCGCAATGCGGCGTATGACCCGGCAGATCCGTGCAGACATTGTGCGGATGATCCACCAGGCCGGCTCCGG
CCACCCCGGAGGATCGCTTTCTGCCGTGGAGATCGTCACCGCGCTCTACTTTGGCGGCGTGATGCGCATCGATCCGGCCA
GACCGGACGATGTGGATCGAGACCGCTTTATTCTCTCCAAGGGGCACTGTGCCCCGGTGCTGTACAGCGCGCTGTGCCGG
CGCGGTTTCTTTGACCCTCACCATCTGGACACGCTGCGCCGTCTGGACAGTATTCTGCAGGGACACCCGCACGCCAGCGT
GGTGCCGGGGTTGGACTGCTCCAGCGGCTCGCTGGGGCAGGGACTGTCGATCGCCAACGGCATCGCCATGGGGCTGCGCA
GGCAGGGGGTTAAGCGGCGCGTGTACTGCCTGCTGGGCGACGGTGAGCTGCAGGAGGGCCAGGTGTGGGAGGCTGCGCTG
ACCGCGGCCCACTACGGTCTGGGCAACGTCTGCGCCATCGTGGATAACAACCATGTGCAGCTGGATGGCACCACGGCAGA
GGTAAAGGGGGTTGAGCCGGTGGCGGATAAGTGGCGTGCCTTCGGCTGGAACGTCCTGTGCGTTGAGGGACACAGTCTGA
GCGCGCTGCTGCAGGCCCTGCGCAGCGTGGTGCTGGAGTCGGTACGCCCCAGCGTCATCATCGCCGATACAATCAAGGGC
AAAGGGGTCTCCTTTATGGAGCACCAGGCCAACTGGCACGGTCAGGCGCCGGATGCGGCGCAGCTGGCTCAGGCTCTGGA
TGAGATCCAGGCATATCAGGAACGGGATCCGGGAGGCCGCGATGAATAA

Upstream 100 bases:

>100_bases
GTTCCTCTGGTCCCTCTTCTGTGTGGTTTTCCTCAGCCTGCTGGCCTGGCTGGGCGTGTTCGGCCTGTTTTAAGTAATTC
CAGTAACGGGAGTCAATCGT

Downstream 100 bases:

>100_bases
GGTTCCGCCGCGTGACGGCTATGGTAACGCCCTGCTGTATCTGGCAGAGCACGATGACAGGCTGGTGGCGCTGGATGCCG
ACGTGGCGAAGTCCACGCGC

Product: transketolase (TK)

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MDITAMRRMTRQIRADIVRMIHQAGSGHPGGSLSAVEIVTALYFGGVMRIDPARPDDVDRDRFILSKGHCAPVLYSALCR
RGFFDPHHLDTLRRLDSILQGHPHASVVPGLDCSSGSLGQGLSIANGIAMGLRRQGVKRRVYCLLGDGELQEGQVWEAAL
TAAHYGLGNVCAIVDNNHVQLDGTTAEVKGVEPVADKWRAFGWNVLCVEGHSLSALLQALRSVVLESVRPSVIIADTIKG
KGVSFMEHQANWHGQAPDAAQLAQALDEIQAYQERDPGGRDE

Sequences:

>Translated_282_residues
MDITAMRRMTRQIRADIVRMIHQAGSGHPGGSLSAVEIVTALYFGGVMRIDPARPDDVDRDRFILSKGHCAPVLYSALCR
RGFFDPHHLDTLRRLDSILQGHPHASVVPGLDCSSGSLGQGLSIANGIAMGLRRQGVKRRVYCLLGDGELQEGQVWEAAL
TAAHYGLGNVCAIVDNNHVQLDGTTAEVKGVEPVADKWRAFGWNVLCVEGHSLSALLQALRSVVLESVRPSVIIADTIKG
KGVSFMEHQANWHGQAPDAAQLAQALDEIQAYQERDPGGRDE
>Mature_282_residues
MDITAMRRMTRQIRADIVRMIHQAGSGHPGGSLSAVEIVTALYFGGVMRIDPARPDDVDRDRFILSKGHCAPVLYSALCR
RGFFDPHHLDTLRRLDSILQGHPHASVVPGLDCSSGSLGQGLSIANGIAMGLRRQGVKRRVYCLLGDGELQEGQVWEAAL
TAAHYGLGNVCAIVDNNHVQLDGTTAEVKGVEPVADKWRAFGWNVLCVEGHSLSALLQALRSVVLESVRPSVIIADTIKG
KGVSFMEHQANWHGQAPDAAQLAQALDEIQAYQERDPGGRDE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=254, Percent_Identity=38.5826771653543, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI205277463, Length=271, Percent_Identity=38.0073800738007, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI4507521, Length=271, Percent_Identity=38.0073800738007, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI225637459, Length=281, Percent_Identity=29.1814946619217, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI225637461, Length=247, Percent_Identity=29.9595141700405, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI225637463, Length=243, Percent_Identity=29.2181069958848, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1788808, Length=248, Percent_Identity=33.0645161290323, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI48994911, Length=254, Percent_Identity=30.3149606299213, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17539652, Length=246, Percent_Identity=41.0569105691057, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6325331, Length=243, Percent_Identity=37.037037037037, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319593, Length=260, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI45551847, Length=251, Percent_Identity=35.8565737051793, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI45550715, Length=251, Percent_Identity=35.8565737051793, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24666278, Length=269, Percent_Identity=34.9442379182156, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24645119, Length=216, Percent_Identity=37.5, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30570; Mature: 30570

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITAMRRMTRQIRADIVRMIHQAGSGHPGGSLSAVEIVTALYFGGVMRIDPARPDDVDR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCC
DRFILSKGHCAPVLYSALCRRGFFDPHHLDTLRRLDSILQGHPHASVVPGLDCSSGSLGQ
CCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GLSIANGIAMGLRRQGVKRRVYCLLGDGELQEGQVWEAALTAAHYGLGNVCAIVDNNHVQ
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCEEE
LDGTTAEVKGVEPVADKWRAFGWNVLCVEGHSLSALLQALRSVVLESVRPSVIIADTIKG
ECCCHHCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
KGVSFMEHQANWHGQAPDAAQLAQALDEIQAYQERDPGGRDE
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDITAMRRMTRQIRADIVRMIHQAGSGHPGGSLSAVEIVTALYFGGVMRIDPARPDDVDR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCC
DRFILSKGHCAPVLYSALCRRGFFDPHHLDTLRRLDSILQGHPHASVVPGLDCSSGSLGQ
CCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GLSIANGIAMGLRRQGVKRRVYCLLGDGELQEGQVWEAALTAAHYGLGNVCAIVDNNHVQ
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCEEE
LDGTTAEVKGVEPVADKWRAFGWNVLCVEGHSLSALLQALRSVVLESVRPSVIIADTIKG
ECCCHHCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
KGVSFMEHQANWHGQAPDAAQLAQALDEIQAYQERDPGGRDE
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]