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The map label for this gene is neuC [H]

Identifier: 238919235

GI number: 238919235

Start: 1309503

End: 1310555

Strand: Direct

Name: neuC [H]

Synonym: NT01EI_1318

Alternate gene names: 238919235

Gene position: 1309503-1310555 (Clockwise)

Preceding gene: 238919234

Following gene: 238919236

Centisome position: 34.35

GC content: 37.42

Gene sequence:

>1053_bases
ATGCATTGCGATCCTAAATATGGGAGCACATATAAAAATATTGTGAGTGATGGGCTTGATTTAAGTAAAGTTATAGATAT
TAATTTAGACTCATCAAGCAATGAAAAAATAATAAATTCAATGTCGCTTTGTCAGAATGCGTTTGCCTCAATTTTCGCTA
ATCATGATTATGATGCTGTCATGATCTTGGGTGACCGTTATGAGATTTTTTCTGTTGCCACTGTGGCGGCTATGAATAAT
ATTCCCCTGATTCATCTTCACGGTGGCGAGAAAACGTTAGGGAATTATGATGAATTTATTCGACATGCAATCACTAAAAT
GAGTAGTCTTCATCTGGTTTCGACAGAGGAATACCGCAAGCGAGTCATTCAATTAGGAGAACATCCCAGCTCAGTTATTA
ATATTGGTGCATTAGGGGCTGAAAATTGTCGTAGCCTCGCATTGCCTGATAAACAGGATTTAGAGTCTCGTTTTGGTTCT
TTGGTTAAGCCGTATTTTGTGGTGGTGTTCCACCCGGAAACGCTGACTAAAGTCTCATTGACGGAGCAAACATTAGCCTT
GATTACGGCGTTAAGCGTATTTTCTGAAGAGTATGATTTCATATTTATTGGCTCTAATGCCGATACAGGCTCAGAAAAGA
TTATTAATATTATTAAGTCATTCTGTTTGCAGAGTGCATCTCGCTATATGATATCAGTGAGCCCTGAAGAATATTTGGGC
TTAGTGAAGTATTCTTGTGGTTTGATAGGTAACTCATCTTCAGGGATTATTGAAGCTCCTTCGCTGAATATTGCAACGAT
TAATATTGGGGATCGGCAGAAGGGGCGTGTTCACGGTGATAGCGTGATTGATGCAGCCTGTACAAAAGCTGCGATCATTG
CGGCGATTGAACTAAGTCAGTCAAGCTGTTTTCAACAAAAAATAGCCATAATCAATAACCCTTATTATAAAAAAAATACG
TTAGAAAATGCTGTTGGAGCTATTGTAAGTTTTTTATTATCAGATAGAAATGTAAACTATAAGGATTTTTATGATATTGA
TCTTGATGTGTAA

Upstream 100 bases:

>100_bases
ATGTGTTACTGGTTCACGCGCTGAATATGGAATTTTACGCCGATTATTAATGTTGCTATCTCGTACGGAGGGGGTCAAGT
TAAGTATCATCGCGACAGGG

Downstream 100 bases:

>100_bases
TGCTTTTTCTTGCTCTTTTTCTAGGAGGGGGTGTGAGTTTACTTAAAGGAATCGGTGTATATCTTACATCGAATATATTA
AATGCACTTATTCCATTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MHCDPKYGSTYKNIVSDGLDLSKVIDINLDSSSNEKIINSMSLCQNAFASIFANHDYDAVMILGDRYEIFSVATVAAMNN
IPLIHLHGGEKTLGNYDEFIRHAITKMSSLHLVSTEEYRKRVIQLGEHPSSVINIGALGAENCRSLALPDKQDLESRFGS
LVKPYFVVVFHPETLTKVSLTEQTLALITALSVFSEEYDFIFIGSNADTGSEKIINIIKSFCLQSASRYMISVSPEEYLG
LVKYSCGLIGNSSSGIIEAPSLNIATINIGDRQKGRVHGDSVIDAACTKAAIIAAIELSQSSCFQQKIAIINNPYYKKNT
LENAVGAIVSFLLSDRNVNYKDFYDIDLDV

Sequences:

>Translated_350_residues
MHCDPKYGSTYKNIVSDGLDLSKVIDINLDSSSNEKIINSMSLCQNAFASIFANHDYDAVMILGDRYEIFSVATVAAMNN
IPLIHLHGGEKTLGNYDEFIRHAITKMSSLHLVSTEEYRKRVIQLGEHPSSVINIGALGAENCRSLALPDKQDLESRFGS
LVKPYFVVVFHPETLTKVSLTEQTLALITALSVFSEEYDFIFIGSNADTGSEKIINIIKSFCLQSASRYMISVSPEEYLG
LVKYSCGLIGNSSSGIIEAPSLNIATINIGDRQKGRVHGDSVIDAACTKAAIIAAIELSQSSCFQQKIAIINNPYYKKNT
LENAVGAIVSFLLSDRNVNYKDFYDIDLDV
>Mature_350_residues
MHCDPKYGSTYKNIVSDGLDLSKVIDINLDSSSNEKIINSMSLCQNAFASIFANHDYDAVMILGDRYEIFSVATVAAMNN
IPLIHLHGGEKTLGNYDEFIRHAITKMSSLHLVSTEEYRKRVIQLGEHPSSVINIGALGAENCRSLALPDKQDLESRFGS
LVKPYFVVVFHPETLTKVSLTEQTLALITALSVFSEEYDFIFIGSNADTGSEKIINIIKSFCLQSASRYMISVSPEEYLG
LVKYSCGLIGNSSSGIIEAPSLNIATINIGDRQKGRVHGDSVIDAACTKAAIIAAIELSQSSCFQQKIAIINNPYYKKNT
LENAVGAIVSFLLSDRNVNYKDFYDIDLDV

Specific function: May be involved in the synthesis of polysialic acid (PSA) [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI190014632, Length=336, Percent_Identity=27.0833333333333, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4885285, Length=338, Percent_Identity=27.2189349112426, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI298566312, Length=338, Percent_Identity=27.2189349112426, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI298566325, Length=336, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020004
- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: NA

Molecular weight: Translated: 38464; Mature: 38464

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCDPKYGSTYKNIVSDGLDLSKVIDINLDSSSNEKIINSMSLCQNAFASIFANHDYDAV
CCCCCCCCCHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
MILGDRYEIFSVATVAAMNNIPLIHLHGGEKTLGNYDEFIRHAITKMSSLHLVSTEEYRK
EEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEECHHHHHH
RVIQLGEHPSSVINIGALGAENCRSLALPDKQDLESRFGSLVKPYFVVVFHPETLTKVSL
HHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEHH
TEQTLALITALSVFSEEYDFIFIGSNADTGSEKIINIIKSFCLQSASRYMISVSPEEYLG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
LVKYSCGLIGNSSSGIIEAPSLNIATINIGDRQKGRVHGDSVIDAACTKAAIIAAIELSQ
HHHHHCCEECCCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCH
SSCFQQKIAIINNPYYKKNTLENAVGAIVSFLLSDRNVNYKDFYDIDLDV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure
MHCDPKYGSTYKNIVSDGLDLSKVIDINLDSSSNEKIINSMSLCQNAFASIFANHDYDAV
CCCCCCCCCHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
MILGDRYEIFSVATVAAMNNIPLIHLHGGEKTLGNYDEFIRHAITKMSSLHLVSTEEYRK
EEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEECHHHHHH
RVIQLGEHPSSVINIGALGAENCRSLALPDKQDLESRFGSLVKPYFVVVFHPETLTKVSL
HHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEHH
TEQTLALITALSVFSEEYDFIFIGSNADTGSEKIINIIKSFCLQSASRYMISVSPEEYLG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
LVKYSCGLIGNSSSGIIEAPSLNIATINIGDRQKGRVHGDSVIDAACTKAAIIAAIELSQ
HHHHHCCEECCCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCH
SSCFQQKIAIINNPYYKKNTLENAVGAIVSFLLSDRNVNYKDFYDIDLDV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1729218 [H]