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The map label for this gene is phoR [H]

Identifier: 238919115

GI number: 238919115

Start: 1179021

End: 1179449

Strand: Direct

Name: phoR [H]

Synonym: NT01EI_1186

Alternate gene names: 238919115

Gene position: 1179021-1179449 (Clockwise)

Preceding gene: 238919114

Following gene: 238919121

Centisome position: 30.93

GC content: 63.87

Gene sequence:

>429_bases
ATGGTCAGCACAGGCTGCGTTTTTAGCATTGATGACACCCTGCGGGTGCGCGGCAATGAGGAGCAGCTGCGCAGCGCTGT
CTCCAATCTGGTGTATAACGCGATCAACCACACACCGGCGGGAACGCAGATTACGGTACGCTGGCAGCGCACCGCGCAGG
GGGCCAGTTTTACCGTACAGGACGATGGACCGGGCATCGCCCGGGAGCACCTCGGTCATCTGACCGAACGCTTTTACCGG
GTCGACCGCTCACGTTCCAGCAGCACCGGCGGCAGCGGGCTGGGACTGGCCATCGTCAAGCATGCGCTGCAGCATCATGA
GGCGCATCTGGCTATCGAGAGCACTCTCGGACAGGGAACCCGCTTCGCGTTTACCCTGCCGTCCCACCTGGTGTTCAACG
GTGCGCCGCCGGTCCGGGTGCCCGGCTAG

Upstream 100 bases:

>100_bases
CTGTCGCGGATTGAGGCGGCGCCAGACATCGATCTCGGCGCGGTGGTTGATGTCCCGGCGATGCTGCATATGCTGGATCG
GGAGGCCAACGCGTTGAGCG

Downstream 100 bases:

>100_bases
CGTGCGCGTCTCCGTCACTCCTCCCGCTGCGTTTCGATCACCAGGCTCCAGCCATCGACGTTGCGCCAGTACTCCTGCTC
CTTCTCCACGTCCAGCTGTA

Product: phosphate regulon sensor protein PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MVSTGCVFSIDDTLRVRGNEEQLRSAVSNLVYNAINHTPAGTQITVRWQRTAQGASFTVQDDGPGIAREHLGHLTERFYR
VDRSRSSSTGGSGLGLAIVKHALQHHEAHLAIESTLGQGTRFAFTLPSHLVFNGAPPVRVPG

Sequences:

>Translated_142_residues
MVSTGCVFSIDDTLRVRGNEEQLRSAVSNLVYNAINHTPAGTQITVRWQRTAQGASFTVQDDGPGIAREHLGHLTERFYR
VDRSRSSSTGGSGLGLAIVKHALQHHEAHLAIESTLGQGTRFAFTLPSHLVFNGAPPVRVPG
>Mature_142_residues
MVSTGCVFSIDDTLRVRGNEEQLRSAVSNLVYNAINHTPAGTQITVRWQRTAQGASFTVQDDGPGIAREHLGHLTERFYR
VDRSRSSSTGGSGLGLAIVKHALQHHEAHLAIESTLGQGTRFAFTLPSHLVFNGAPPVRVPG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=124, Percent_Identity=69.3548387096774, Blast_Score=189, Evalue=8e-50,
Organism=Escherichia coli, GI1786783, Length=117, Percent_Identity=45.2991452991453, Blast_Score=95, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=112, Percent_Identity=38.3928571428571, Blast_Score=79, Evalue=8e-17,
Organism=Escherichia coli, GI1788393, Length=120, Percent_Identity=30.8333333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=113, Percent_Identity=38.9380530973451, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=91, Percent_Identity=40.6593406593407, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 15341; Mature: 15341

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTGCVFSIDDTLRVRGNEEQLRSAVSNLVYNAINHTPAGTQITVRWQRTAQGASFTVQ
CCCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
DDGPGIAREHLGHLTERFYRVDRSRSSSTGGSGLGLAIVKHALQHHEAHLAIESTLGQGT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEHHCCCCC
RFAFTLPSHLVFNGAPPVRVPG
EEEEECCCCEEECCCCCCCCCC
>Mature Secondary Structure
MVSTGCVFSIDDTLRVRGNEEQLRSAVSNLVYNAINHTPAGTQITVRWQRTAQGASFTVQ
CCCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
DDGPGIAREHLGHLTERFYRVDRSRSSSTGGSGLGLAIVKHALQHHEAHLAIESTLGQGT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEHHCCCCC
RFAFTLPSHLVFNGAPPVRVPG
EEEEECCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]