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The map label for this gene is gyrI [H]

Identifier: 238919108

GI number: 238919108

Start: 1171369

End: 1171836

Strand: Direct

Name: gyrI [H]

Synonym: NT01EI_1179

Alternate gene names: 238919108

Gene position: 1171369-1171836 (Clockwise)

Preceding gene: 238919107

Following gene: 238919109

Centisome position: 30.73

GC content: 66.88

Gene sequence:

>468_bases
ATGCAGGTCAGGATCGTGAGTCTGGCGGCGCAGCCGCTGTTTGTCCTGCGTGTACAGGGGCCGTTTGCACAGTCGTTGGG
GCCGGGATTTGAGCGGCTGATGGCGTGGTCGGCGCGCCATGGCCTGCGGGGGCAGTGGATGGCGCTGTACTATGACAACC
CCCGCGAGGTCGCGCCAGATGCGCTGCGGGCGGACGTGGCCCTGACGACGGCGTCGGTGACGCTCCCATCGGATGGCGAG
GCGTACGGGATCCGTCGGGGCGCGCTGGCCGGGGGGCTGTATGCGCTGGCACAGGTGCGGGTCACCGATAATGACTTTGC
CACGCCGTGGATAGCCCTGTTTGACCAGGCGCTGCCCGCCTGTGGCTATCGTCCGGACGGCGGACCCTGCTTTGAGCGCT
ATCTGAGTGATGGACGGGGCAGCGGTGAGTGGTTGCTGGAGCTGGGGGTGCCGGTCAGAAAAAACTGA

Upstream 100 bases:

>100_bases
GGCGCCGCGTGGCTGTGGCCCGCGTAACGGCGGGATGCCCGGAAATTTGCCATACTGGCAGAGGCGCCGACATGGCGCGC
GGGGAGGGGAGTCGAGGGTT

Downstream 100 bases:

>100_bases
AAATGCCCCTTCGCCGTCGTCGGGGCGCCGGAGATATGCTCCGGCAATGGTGCTTTCGCCGGGGAGGCGCGGGTATGGCT
AATTTGTCACAGTTTATTGC

Product: transcription activator, effector binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQVRIVSLAAQPLFVLRVQGPFAQSLGPGFERLMAWSARHGLRGQWMALYYDNPREVAPDALRADVALTTASVTLPSDGE
AYGIRRGALAGGLYALAQVRVTDNDFATPWIALFDQALPACGYRPDGGPCFERYLSDGRGSGEWLLELGVPVRKN

Sequences:

>Translated_155_residues
MQVRIVSLAAQPLFVLRVQGPFAQSLGPGFERLMAWSARHGLRGQWMALYYDNPREVAPDALRADVALTTASVTLPSDGE
AYGIRRGALAGGLYALAQVRVTDNDFATPWIALFDQALPACGYRPDGGPCFERYLSDGRGSGEWLLELGVPVRKN
>Mature_155_residues
MQVRIVSLAAQPLFVLRVQGPFAQSLGPGFERLMAWSARHGLRGQWMALYYDNPREVAPDALRADVALTTASVTLPSDGE
AYGIRRGALAGGLYALAQVRVTDNDFATPWIALFDQALPACGYRPDGGPCFERYLSDGRGSGEWLLELGVPVRKN

Specific function: Inhibits the supercoiling activity of DNA gyrase. Protects cells from the DNA replication inhibitor microcin B17 (MccB17). Blocks MccB17 export from producing cells [H]

COG id: COG3449

COG function: function code L; DNA gyrase inhibitor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788319, Length=140, Percent_Identity=37.8571428571429, Blast_Score=103, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind [H]

EC number: NA

Molecular weight: Translated: 16881; Mature: 16881

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVRIVSLAAQPLFVLRVQGPFAQSLGPGFERLMAWSARHGLRGQWMALYYDNPREVAPD
CEEEEEEECCCCEEEEEECCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCCH
ALRADVALTTASVTLPSDGEAYGIRRGALAGGLYALAQVRVTDNDFATPWIALFDQALPA
HHHHCEEEEEEEEECCCCCCCCCEECCHHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCC
CGYRPDGGPCFERYLSDGRGSGEWLLELGVPVRKN
CCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MQVRIVSLAAQPLFVLRVQGPFAQSLGPGFERLMAWSARHGLRGQWMALYYDNPREVAPD
CEEEEEEECCCCEEEEEECCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCCH
ALRADVALTTASVTLPSDGEAYGIRRGALAGGLYALAQVRVTDNDFATPWIALFDQALPA
HHHHCEEEEEEEEECCCCCCCCCEECCHHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCC
CGYRPDGGPCFERYLSDGRGSGEWLLELGVPVRKN
CCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]