Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 238919040

GI number: 238919040

Start: 1103123

End: 1105081

Strand: Direct

Name: dnaX [H]

Synonym: NT01EI_1108

Alternate gene names: 238919040

Gene position: 1103123-1105081 (Clockwise)

Preceding gene: 238919039

Following gene: 238919041

Centisome position: 28.94

GC content: 64.57

Gene sequence:

>1959_bases
ATGAGCTACCAGGTTCTCGCCCGCAAGTGGCGTCCACAAACCTTTGCTGACGTCGTGGGTCAGGAGCATGTCCTGACGGC
ACTGGCAAACGGGCTCTCTCTGGGCCGTATTCACCATGCCTATCTGTTTTCCGGTACCCGCGGGGTCGGCAAGACCAGTA
TCGCCCGTCTGTTGGCCAAGGGGCTGAACTGTGAAACCGGGATCACCGCCACGCCGTGCGGCGTCTGCGACAACTGTCGG
GAGATCGAGCAGGGGCGTTTTGTCGACCTGCTGGAGATCGATGCTGCCTCGCGCACCAAGGTCGAAGACACGCGTGACCT
GCTGGATAACGTGCAGTATGCCCCGGCGCGCGGTCGGTTCAAGGTCTACCTGATCGACGAAGTCCACATGCTGTCGCGCC
ACAGCTTCAACGCGCTGTTGAAAACGCTGGAGGAGCCGCCGCCGCACGTCAAGTTTCTGCTGGCTACCACCGATCCACAG
AAGCTGCCGGTCACCATCCTGTCGCGCTGTCTGCAGTTTCATCTGCGTGCGCTGGATCATGAGCAGATCCGGGCGCAGCT
GGAGAAAATCGCCCATGCCGAGGCCCTGACGGCGGAGCCGCGGGCGCTACAGCTGCTGGCACGCGCCGCCGAAGGCAGCA
TGCGTGATGCTCTGAGCCTGATGGATCAGGCGATCGCCATGGGGCAGGGGCAGATTACCGCCGATACCGTCAGCCAGATG
CTGGGAACGCTGGATGATGAGCAGCCCCTGGCGCTGATCGAGGCGCTGACCGCGGCGGATGGCGCGCTGGTGATGGCGCG
GGTAGAGCAGGCCGCCGGGCGCGGCGTGGACTGGGAGAACCTGCTGGTCGAGATGCTGGCGCTGCTGCACCGGGTTGCGA
TGCTACAGCTGCTGCCCAGCGCGCTGGACAGCCAGTTCGCGGCGGTAGAACCGCGTCTGCGTGAGCTGGCGCGGATGCTG
CCGCCGGCGGACCTGCAGCTGTTTTACCAGATTATCCTCAACGGCCGTAAAGAGCTGGCCTTTGCGCCGGACCGGCGCAT
GGGGGCTGAAATGACCCTGCTGCGTGCGCTGGCCTTTCATCCTAAGGCGGTGATTGCCGAGCTGAGCTCCGCGCCGTCAG
CGGTGCAGGGCAGCGATATCCTCACGGTCTCCGCCGCGGCGGTGCAGGGCGTCGTGTCGCCGGCGCCCGAGCCGACTGTG
ATGCTTCAGACAGTGAATGTACCGGCGGCGGGCGCCGTGCCGGAGAGCACTGCGCAGCTATTACAGGCCCGCTCACGCCT
GCGGCAAAAGGCCGCCGGAGGGAGTGAGCCAAAAAAGAGTGAGCCGGCGGCACTGCAGCGTGCGCAGCCGGCCTCTTCAG
CGCTGGAGCGTCTGGCCAGCATAAGCGAACGGGGTCAGCAGAAGATCGCGTCGGCGGAGCAAGAGCAGGCGTCGGCGCGT
AAAGAGGCTTATCGCTGGAAGGCACAGAACCGCCCCGTAGAGAAAAAGGCGCCCAAGACGACGCCCAGGGCGTTGCGCAG
CGCACTGGAGCATGAGAAAACGCCGGAGCTGGCGGAGCGCCTGGCGCAGGAGTCGCTGACGCGGGATGAGTGGGCCCGGG
AGCTGAGTCAGCTGCGGCTGCCAAAGCTGGTGCAGCAGCTGGCGCTGAATGCGTTTCGTGAGCCCGCACCGGAGGGAAGT
GTGCTTCTGCATTTACGTTCAGCCCAGCGTCATTTAAACTCCGCCTCTGCGCAGCAAATGCTGGCGCAGGCCCTGAGCGG
CCACTATGGGCATCCGGTGGCTCTGAGCATTGTCGAGGATGACGATCCTCAACGACGCACGCCGCTGGAGTGGCGCCAGG
CTATCTATGAAGAGAGTTTGGCGCAGGCCCGCGCATCGATTGCAGCGGATGGCAATATCCAGACCCTGCGGCGTCTGTTC
GATGCCGAGCTGGATGAAGAGAGCATCCGCCCCGTTTAA

Upstream 100 bases:

>100_bases
AGGCGGGCGCCAGTGCCCGTCCCATGCCATCAGTCTGACGCCGCTGGCCGTCTGTGGGACGGCTGGCGAATTTTCTTATT
CTATCAGCGACGAATCATCA

Downstream 100 bases:

>100_bases
CCGCTGTGCCGCTGCGGCACGGCCCTACGAAAAGAGAGAACGCTATGTTTGGTAAAGGCGGACTGGGTAACCTGATGAAA
CAGGCCCAGCAGATGCAGGA

Product: DNA polymerase III subunit tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR
EIEQGRFVDLLEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPHVKFLLATTDPQ
KLPVTILSRCLQFHLRALDHEQIRAQLEKIAHAEALTAEPRALQLLARAAEGSMRDALSLMDQAIAMGQGQITADTVSQM
LGTLDDEQPLALIEALTAADGALVMARVEQAAGRGVDWENLLVEMLALLHRVAMLQLLPSALDSQFAAVEPRLRELARML
PPADLQLFYQIILNGRKELAFAPDRRMGAEMTLLRALAFHPKAVIAELSSAPSAVQGSDILTVSAAAVQGVVSPAPEPTV
MLQTVNVPAAGAVPESTAQLLQARSRLRQKAAGGSEPKKSEPAALQRAQPASSALERLASISERGQQKIASAEQEQASAR
KEAYRWKAQNRPVEKKAPKTTPRALRSALEHEKTPELAERLAQESLTRDEWARELSQLRLPKLVQQLALNAFREPAPEGS
VLLHLRSAQRHLNSASAQQMLAQALSGHYGHPVALSIVEDDDPQRRTPLEWRQAIYEESLAQARASIAADGNIQTLRRLF
DAELDEESIRPV

Sequences:

>Translated_652_residues
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR
EIEQGRFVDLLEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPHVKFLLATTDPQ
KLPVTILSRCLQFHLRALDHEQIRAQLEKIAHAEALTAEPRALQLLARAAEGSMRDALSLMDQAIAMGQGQITADTVSQM
LGTLDDEQPLALIEALTAADGALVMARVEQAAGRGVDWENLLVEMLALLHRVAMLQLLPSALDSQFAAVEPRLRELARML
PPADLQLFYQIILNGRKELAFAPDRRMGAEMTLLRALAFHPKAVIAELSSAPSAVQGSDILTVSAAAVQGVVSPAPEPTV
MLQTVNVPAAGAVPESTAQLLQARSRLRQKAAGGSEPKKSEPAALQRAQPASSALERLASISERGQQKIASAEQEQASAR
KEAYRWKAQNRPVEKKAPKTTPRALRSALEHEKTPELAERLAQESLTRDEWARELSQLRLPKLVQQLALNAFREPAPEGS
VLLHLRSAQRHLNSASAQQMLAQALSGHYGHPVALSIVEDDDPQRRTPLEWRQAIYEESLAQARASIAADGNIQTLRRLF
DAELDEESIRPV
>Mature_651_residues
SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCRE
IEQGRFVDLLEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPHVKFLLATTDPQK
LPVTILSRCLQFHLRALDHEQIRAQLEKIAHAEALTAEPRALQLLARAAEGSMRDALSLMDQAIAMGQGQITADTVSQML
GTLDDEQPLALIEALTAADGALVMARVEQAAGRGVDWENLLVEMLALLHRVAMLQLLPSALDSQFAAVEPRLRELARMLP
PADLQLFYQIILNGRKELAFAPDRRMGAEMTLLRALAFHPKAVIAELSSAPSAVQGSDILTVSAAAVQGVVSPAPEPTVM
LQTVNVPAAGAVPESTAQLLQARSRLRQKAAGGSEPKKSEPAALQRAQPASSALERLASISERGQQKIASAEQEQASARK
EAYRWKAQNRPVEKKAPKTTPRALRSALEHEKTPELAERLAQESLTRDEWARELSQLRLPKLVQQLALNAFREPAPEGSV
LLHLRSAQRHLNSASAQQMLAQALSGHYGHPVALSIVEDDDPQRRTPLEWRQAIYEESLAQARASIAADGNIQTLRRLFD
AELDEESIRPV

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=310, Percent_Identity=23.8709677419355, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI194306571, Length=313, Percent_Identity=23.6421725239617, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI194306567, Length=313, Percent_Identity=23.6421725239617, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786676, Length=653, Percent_Identity=68.9127105666156, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI1787341, Length=139, Percent_Identity=31.6546762589928, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=247, Percent_Identity=23.4817813765182, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=243, Percent_Identity=25.5144032921811, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324478, Length=259, Percent_Identity=24.7104247104247, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322528, Length=263, Percent_Identity=23.574144486692, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921076, Length=313, Percent_Identity=25.5591054313099, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647857, Length=251, Percent_Identity=26.6932270916335, Blast_Score=76, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 71474; Mature: 71343

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAK
CCHHHHHHHCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
GLNCETGITATPCGVCDNCREIEQGRFVDLLEIDAASRTKVEDTRDLLDNVQYAPARGRF
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPPHVKFLLATTDPQKLPVTILSRCLQFHLRALDH
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
EQIRAQLEKIAHAEALTAEPRALQLLARAAEGSMRDALSLMDQAIAMGQGQITADTVSQM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGTLDDEQPLALIEALTAADGALVMARVEQAAGRGVDWENLLVEMLALLHRVAMLQLLPS
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALDSQFAAVEPRLRELARMLPPADLQLFYQIILNGRKELAFAPDRRMGAEMTLLRALAFH
HHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCCCHHCCHHHHHHHHHHHC
PKAVIAELSSAPSAVQGSDILTVSAAAVQGVVSPAPEPTVMLQTVNVPAAGAVPESTAQL
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
LQARSRLRQKAAGGSEPKKSEPAALQRAQPASSALERLASISERGQQKIASAEQEQASAR
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAYRWKAQNRPVEKKAPKTTPRALRSALEHEKTPELAERLAQESLTRDEWARELSQLRL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PKLVQQLALNAFREPAPEGSVLLHLRSAQRHLNSASAQQMLAQALSGHYGHPVALSIVED
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DDPQRRTPLEWRQAIYEESLAQARASIAADGNIQTLRRLFDAELDEESIRPV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAK
CHHHHHHHCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
GLNCETGITATPCGVCDNCREIEQGRFVDLLEIDAASRTKVEDTRDLLDNVQYAPARGRF
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPPHVKFLLATTDPQKLPVTILSRCLQFHLRALDH
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
EQIRAQLEKIAHAEALTAEPRALQLLARAAEGSMRDALSLMDQAIAMGQGQITADTVSQM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGTLDDEQPLALIEALTAADGALVMARVEQAAGRGVDWENLLVEMLALLHRVAMLQLLPS
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALDSQFAAVEPRLRELARMLPPADLQLFYQIILNGRKELAFAPDRRMGAEMTLLRALAFH
HHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCCCHHCCHHHHHHHHHHHC
PKAVIAELSSAPSAVQGSDILTVSAAAVQGVVSPAPEPTVMLQTVNVPAAGAVPESTAQL
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
LQARSRLRQKAAGGSEPKKSEPAALQRAQPASSALERLASISERGQQKIASAEQEQASAR
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAYRWKAQNRPVEKKAPKTTPRALRSALEHEKTPELAERLAQESLTRDEWARELSQLRL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PKLVQQLALNAFREPAPEGSVLLHLRSAQRHLNSASAQQMLAQALSGHYGHPVALSIVED
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DDPQRRTPLEWRQAIYEESLAQARASIAADGNIQTLRRLFDAELDEESIRPV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]