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The map label for this gene is glcK [H]

Identifier: 238917910

GI number: 238917910

Start: 2060039

End: 2060980

Strand: Reverse

Name: glcK [H]

Synonym: EUBELI_01997

Alternate gene names: 238917910

Gene position: 2060980-2060039 (Counterclockwise)

Preceding gene: 238917911

Following gene: 238917909

Centisome position: 96.12

GC content: 43.42

Gene sequence:

>942_bases
ATGAGTAAGATTATATTTGGAATTGATGTTGGAGGAACAACCTGCAAATGTGGTACATTTTCTAAAGAAGGTGAGCTGTT
AAGAAAAGAAGAGATTCCTACAAGAAAGGATGAGGGTGGAAGCCTGATTCTGCCTGATATAAGTGAGTATATCAAGGGCG
TTCTTGCAGATATGAATATGACAACAGAGGATGTGGCAGGAATCGGAATGGGACTTCCTGGTGCATGTCTTGAGGATGGA
ACTGTCAACAAATGTATCAACTTGGGCTGGGGAGTATTTAATGCAGCCAATGCACTGTCTGAGCTTACAGGTATTCCTGT
TAAGATTGGTAATGATGCAAATATGGCAGCACTCGGAGAATTCTGGGTAGGCGGTGGAAGCGAATATAACAGCATGGTAA
TGGTGACGATTGGAACCGGTGTAGGCGGTGGAGTTATTATTGATGGAAAGCCTCTTTATGGATTTAACGGTGCAGCAGGT
GAGATAGGTCATCTTCCACTTGTTGAAGGTGAGACTGAGAGCTGTAACTGTGGAAAGAAGGGCTGTCTTGAGCAGGTTGC
TTCTGCAACTGGAATTGTAAGAACGGCTAACCGTATGCTTGCAGAAAGTGACATGCCTTCATCTTTAAGAAGTGTGCCAT
ACATATCGGCAAAGGTTATATTTGACGAGGCTAAGGGAGGAGATGCCCTTGCTATACAGGTAACAGAGTATGTATGCAGG
TATCTTGGAAAAGGACTTGCATGTGCAGCGGGAATGGTTGACCCGGAGGTATTTGTAATTGGTGGCGGAGTTTCTGCCGC
AGGGGAATATTTTATCAATCTTATTGATAAGTATTATAAGGAATGTGTGTTCCATGCGAGCAGACAGACTAAGATAGTTA
AGGCTGCTCTTGGTAATGATGCAGGAATGTATGGAGCAGCAAAGCTTATTCTTGGAAATTAG

Upstream 100 bases:

>100_bases
GCAGCGGTCAACCACAGACAGAAGATGATGGGATATAATGCAGCGAAGGAATTATACAGAAGAGTACAGGAAAATCTTAT
GAGAGGAGGGGAAGATGACG

Downstream 100 bases:

>100_bases
TATTAAGGATAGTGAGATTATATGGATAATAAAATGTTATCAGAAGCATTAATATCAATGCTTGGTGCCGGGAATGTAAG
AACAGGTGAACTAATGAAGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKIIFGIDVGGTTCKCGTFSKEGELLRKEEIPTRKDEGGSLILPDISEYIKGVLADMNMTTEDVAGIGMGLPGACLEDG
TVNKCINLGWGVFNAANALSELTGIPVKIGNDANMAALGEFWVGGGSEYNSMVMVTIGTGVGGGVIIDGKPLYGFNGAAG
EIGHLPLVEGETESCNCGKKGCLEQVASATGIVRTANRMLAESDMPSSLRSVPYISAKVIFDEAKGGDALAIQVTEYVCR
YLGKGLACAAGMVDPEVFVIGGGVSAAGEYFINLIDKYYKECVFHASRQTKIVKAALGNDAGMYGAAKLILGN

Sequences:

>Translated_313_residues
MSKIIFGIDVGGTTCKCGTFSKEGELLRKEEIPTRKDEGGSLILPDISEYIKGVLADMNMTTEDVAGIGMGLPGACLEDG
TVNKCINLGWGVFNAANALSELTGIPVKIGNDANMAALGEFWVGGGSEYNSMVMVTIGTGVGGGVIIDGKPLYGFNGAAG
EIGHLPLVEGETESCNCGKKGCLEQVASATGIVRTANRMLAESDMPSSLRSVPYISAKVIFDEAKGGDALAIQVTEYVCR
YLGKGLACAAGMVDPEVFVIGGGVSAAGEYFINLIDKYYKECVFHASRQTKIVKAALGNDAGMYGAAKLILGN
>Mature_312_residues
SKIIFGIDVGGTTCKCGTFSKEGELLRKEEIPTRKDEGGSLILPDISEYIKGVLADMNMTTEDVAGIGMGLPGACLEDGT
VNKCINLGWGVFNAANALSELTGIPVKIGNDANMAALGEFWVGGGSEYNSMVMVTIGTGVGGGVIIDGKPLYGFNGAAGE
IGHLPLVEGETESCNCGKKGCLEQVASATGIVRTANRMLAESDMPSSLRSVPYISAKVIFDEAKGGDALAIQVTEYVCRY
LGKGLACAAGMVDPEVFVIGGGVSAAGEYFINLIDKYYKECVFHASRQTKIVKAALGNDAGMYGAAKLILGN

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=284, Percent_Identity=26.7605633802817, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI298566325, Length=284, Percent_Identity=26.7605633802817, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4885285, Length=284, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI190014632, Length=284, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081733, Length=316, Percent_Identity=30.0632911392405, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787363, Length=324, Percent_Identity=28.7037037037037, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786891, Length=316, Percent_Identity=27.2151898734177, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787878, Length=293, Percent_Identity=27.6450511945392, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082230, Length=286, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=323, Percent_Identity=24.4582043343653, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32524; Mature: 32393

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIFGIDVGGTTCKCGTFSKEGELLRKEEIPTRKDEGGSLILPDISEYIKGVLADMNM
CCEEEEEEECCCCEEECCCCCCCCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCCC
TTEDVAGIGMGLPGACLEDGTVNKCINLGWGVFNAANALSELTGIPVKIGNDANMAALGE
CHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEEHHH
FWVGGGSEYNSMVMVTIGTGVGGGVIIDGKPLYGFNGAAGEIGHLPLVEGETESCNCGKK
HHCCCCCCCCCEEEEEEECCCCCCEEECCCEECCCCCCCCCCCCCCEECCCCCCCCCCHH
GCLEQVASATGIVRTANRMLAESDMPSSLRSVPYISAKVIFDEAKGGDALAIQVTEYVCR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCEEEEEHHHHHHH
YLGKGLACAAGMVDPEVFVIGGGVSAAGEYFINLIDKYYKECVFHASRQTKIVKAALGND
HHCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCC
AGMYGAAKLILGN
CCCCCEEEEEECC
>Mature Secondary Structure 
SKIIFGIDVGGTTCKCGTFSKEGELLRKEEIPTRKDEGGSLILPDISEYIKGVLADMNM
CEEEEEEECCCCEEECCCCCCCCCHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHCCCC
TTEDVAGIGMGLPGACLEDGTVNKCINLGWGVFNAANALSELTGIPVKIGNDANMAALGE
CHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEEHHH
FWVGGGSEYNSMVMVTIGTGVGGGVIIDGKPLYGFNGAAGEIGHLPLVEGETESCNCGKK
HHCCCCCCCCCEEEEEEECCCCCCEEECCCEECCCCCCCCCCCCCCEECCCCCCCCCCHH
GCLEQVASATGIVRTANRMLAESDMPSSLRSVPYISAKVIFDEAKGGDALAIQVTEYVCR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCCCEEEEEHHHHHHH
YLGKGLACAAGMVDPEVFVIGGGVSAAGEYFINLIDKYYKECVFHASRQTKIVKAALGND
HHCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCC
AGMYGAAKLILGN
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]