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The map label for this gene is murB [H]

Identifier: 238917909

GI number: 238917909

Start: 2059082

End: 2060017

Strand: Reverse

Name: murB [H]

Synonym: EUBELI_01996

Alternate gene names: 238917909

Gene position: 2060017-2059082 (Counterclockwise)

Preceding gene: 238917910

Following gene: 238917908

Centisome position: 96.07

GC content: 41.45

Gene sequence:

>936_bases
ATGGATAATAAAATGTTATCAGAAGCATTAATATCAATGCTTGGTGCCGGGAATGTAAGAACAGGTGAACTAATGAAGAC
ACATACTACATTCAGAATCGGAGGTGCTGCAGATTATTATGTAACACCACAGGCAGAAAAGCAGATAGCAGATGTTATCG
CATTTTTGAAAAAATCGGACATTAAATATATTGTTATTGGAAATGGCAGTAATATTCTTGTGAGTGATGAAGGCTTCAGG
GGAGTTGTAGTTGAGCTTGGCGATGGTTTTTCAGATTATGAGTTTCTGCAGGATTCACAGGATAATTCAGATGAAGTGCT
TGTCAAAGCAAGTGCAGGTATGAAGCTTACAAGACTTGGCAACCAGCTTGCTGCTAATGGAATTGCTGGATTTGAATTTG
CAACAGGTATTCCGGGCTGCATAGGTGGTGCTGTAAGAATGAATGCAGGTGCTTATGGCGGGGAGTTCAAGGATATTCTT
GTCAGTGCAAAGGTTATTGATGATGAAGGTGTTATCAGGGAGCTTTCAGCAGATGAACTTGAGCTTGGATACAGAACAAG
TATTGTAGCGAAAAGCAATATGATTGTTCTTGAAGCAACTTTGAAATTAAGAAAAGGTGAACCGGATATAATAAGAAATA
ATATCTCAGAGCTGGCAGCTAAGAGAAGGCAGAAGCAGCCACTTGAGTATCCTAGTGCCGGAAGCACATTTAAAAGACCG
GAAGGATATTTTGCAGCAAAGCTTATTGAGGATGCAGGTCTTAAGGGTTGTGCAAGAGGTGGCGCACAGGTATCGGAGAA
GCATGCCGGATTCGTTGTCAATAAGGGCGATGCAACTGCGAAGGATGTATGCGAGCTTACGGATTATATTAAGAGTGAAG
TTATGGGAAAGTTCGGTGTCGGGCTGGAACTGGAAGTTGTAAAGGTTGGATTCTAA

Upstream 100 bases:

>100_bases
ACAGACTAAGATAGTTAAGGCTGCTCTTGGTAATGATGCAGGAATGTATGGAGCAGCAAAGCTTATTCTTGGAAATTAGT
ATTAAGGATAGTGAGATTAT

Downstream 100 bases:

>100_bases
GGCTTGTTATAATTAAACAGACCAGTAATTAAAGGCAGATAAGAAAGAGAAGATGATAAGATGAAGATGATTATTGTTAC
AGGTATGTCAGGTGCAGGTA

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDNKMLSEALISMLGAGNVRTGELMKTHTTFRIGGAADYYVTPQAEKQIADVIAFLKKSDIKYIVIGNGSNILVSDEGFR
GVVVELGDGFSDYEFLQDSQDNSDEVLVKASAGMKLTRLGNQLAANGIAGFEFATGIPGCIGGAVRMNAGAYGGEFKDIL
VSAKVIDDEGVIRELSADELELGYRTSIVAKSNMIVLEATLKLRKGEPDIIRNNISELAAKRRQKQPLEYPSAGSTFKRP
EGYFAAKLIEDAGLKGCARGGAQVSEKHAGFVVNKGDATAKDVCELTDYIKSEVMGKFGVGLELEVVKVGF

Sequences:

>Translated_311_residues
MDNKMLSEALISMLGAGNVRTGELMKTHTTFRIGGAADYYVTPQAEKQIADVIAFLKKSDIKYIVIGNGSNILVSDEGFR
GVVVELGDGFSDYEFLQDSQDNSDEVLVKASAGMKLTRLGNQLAANGIAGFEFATGIPGCIGGAVRMNAGAYGGEFKDIL
VSAKVIDDEGVIRELSADELELGYRTSIVAKSNMIVLEATLKLRKGEPDIIRNNISELAAKRRQKQPLEYPSAGSTFKRP
EGYFAAKLIEDAGLKGCARGGAQVSEKHAGFVVNKGDATAKDVCELTDYIKSEVMGKFGVGLELEVVKVGF
>Mature_311_residues
MDNKMLSEALISMLGAGNVRTGELMKTHTTFRIGGAADYYVTPQAEKQIADVIAFLKKSDIKYIVIGNGSNILVSDEGFR
GVVVELGDGFSDYEFLQDSQDNSDEVLVKASAGMKLTRLGNQLAANGIAGFEFATGIPGCIGGAVRMNAGAYGGEFKDIL
VSAKVIDDEGVIRELSADELELGYRTSIVAKSNMIVLEATLKLRKGEPDIIRNNISELAAKRRQKQPLEYPSAGSTFKRP
EGYFAAKLIEDAGLKGCARGGAQVSEKHAGFVVNKGDATAKDVCELTDYIKSEVMGKFGVGLELEVVKVGF

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33294; Mature: 33294

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKMLSEALISMLGAGNVRTGELMKTHTTFRIGGAADYYVTPQAEKQIADVIAFLKKSD
CCHHHHHHHHHHHHCCCCCCCCCEEEEECEEEECCCEEEEECCHHHHHHHHHHHHHHHCC
IKYIVIGNGSNILVSDEGFRGVVVELGDGFSDYEFLQDSQDNSDEVLVKASAGMKLTRLG
CEEEEEECCCEEEEECCCCCEEEEEECCCCCHHHHHHCCCCCCCEEEEEECCCEEHHHHC
NQLAANGIAGFEFATGIPGCIGGAVRMNAGAYGGEFKDILVSAKVIDDEGVIRELSADEL
HHHHHCCCCCCHHHCCCCHHHCCCEEECCCCCCCCHHHHEEEEEEECCCCHHHHCCCCHH
ELGYRTSIVAKSNMIVLEATLKLRKGEPDIIRNNISELAAKRRQKQPLEYPSAGSTFKRP
CCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EGYFAAKLIEDAGLKGCARGGAQVSEKHAGFVVNKGDATAKDVCELTDYIKSEVMGKFGV
CCHHHHHHHHHCCCCHHHCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
GLELEVVKVGF
CEEEEEEEECC
>Mature Secondary Structure
MDNKMLSEALISMLGAGNVRTGELMKTHTTFRIGGAADYYVTPQAEKQIADVIAFLKKSD
CCHHHHHHHHHHHHCCCCCCCCCEEEEECEEEECCCEEEEECCHHHHHHHHHHHHHHHCC
IKYIVIGNGSNILVSDEGFRGVVVELGDGFSDYEFLQDSQDNSDEVLVKASAGMKLTRLG
CEEEEEECCCEEEEECCCCCEEEEEECCCCCHHHHHHCCCCCCCEEEEEECCCEEHHHHC
NQLAANGIAGFEFATGIPGCIGGAVRMNAGAYGGEFKDILVSAKVIDDEGVIRELSADEL
HHHHHCCCCCCHHHCCCCHHHCCCEEECCCCCCCCHHHHEEEEEEECCCCHHHHCCCCHH
ELGYRTSIVAKSNMIVLEATLKLRKGEPDIIRNNISELAAKRRQKQPLEYPSAGSTFKRP
CCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EGYFAAKLIEDAGLKGCARGGAQVSEKHAGFVVNKGDATAKDVCELTDYIKSEVMGKFGV
CCHHHHHHHHHCCCCHHHCCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
GLELEVVKVGF
CEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA