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The map label for this gene is galK [H]

Identifier: 238917765

GI number: 238917765

Start: 1904625

End: 1905881

Strand: Reverse

Name: galK [H]

Synonym: EUBELI_01846

Alternate gene names: 238917765

Gene position: 1905881-1904625 (Counterclockwise)

Preceding gene: 238917766

Following gene: 238917764

Centisome position: 88.89

GC content: 40.73

Gene sequence:

>1257_bases
ATGATTAACGGGAGAATGTGTGATGATGTATTGACTGATATTTATGTGGACAAAGACAAACTTCCATATGAAAGAAAACG
ATATATAGAAGCCATTGAACAGTATATTACACGATTCGGCGATGATGATGTTTGGATATATAGTGCTCCGGGCAGAAGTG
AGATTGGAGGAAATCATACGGATCATCAGCATGGGGAGGTTTTGGCTGCATCTATTAACCATGATGCTATCGCTGTTGCA
AAAAAATTAGACGATCAAGTAGTCCGTATTGTATCGGACGGTTATAATAATCTGATTGCGATTCATTTGGATGACTTAGA
TAAGAAAGATAAAGAAGAAGGAAGCACCCAAGCATTGATTCGTGGCGTATTAGCAAAGACAAAAGAGAATGGGCATACAA
TCGGTGGATTTCAGGCATATATTACCAGCGATGTGCTGATTGGAGCAGGGTTATCTTCCTCGGCAGCATTTGAAACTCTG
ATTGGAACTATCTTATCCTACATGTACAATCAAGGCAATATATCAGCGATTGAGATTGCTATGATCGGACAGTACGCAGA
GAATGTGTACTTTGGAAAACCATGTGGATTGATGGATCAGATGGCTTGCTCGGTTGGAAGTCTGGTGCATATCAATTTTG
AGAATCCTCAAAAACCAGAGGTGGAGCGTGTTGAATTTGATCTTGATGTACATGGATACAGTTTATGTATTACAGATACC
AAGGGTTCTCACGCAGATCTTACACCGGACTATGCAGCAATACCGATGGAGATGAAACAGGCGGCAGCATGTTTCGGTAA
AGAAGTATTAGGAGAAGTATCAAAGAAAGAAATCCTTAGTAATTTATCTAAGATACGTGCAGAGGCAGGAGATAGGGCGG
CACTTCGTGCTTTACACTTTATATGTGAGAATGAACGGGTACAAAAGGAAGTAGATGCTTTAAAGAAAGACAACTTTTCA
GAGTTCCTTTTATTGGTAAAGAAATCGGGAGATTCATCCTTTAAGTATCTTCAAAATGTATTTACATGTCATGATGTCAG
CCATCAGAATGTATCGGTAGCACTGGCGGTGAGTGAAATCCTATTGGAAGATAAAGGCGTATGCCGAGTGCACGGAGGTG
GTTTCGCAGGAACAATTCAGGCGTTTGTTCCAAACGAGCTTGTGGAACATTACAAGACTGGGATGGAAGAAGTGTTTGGA
AGCGGAGCTTGCGATGTGTTGAAGATTCGTAAGTATGGTGGCATTAAGGTAATTTAG

Upstream 100 bases:

>100_bases
ATATGTAATGAAAAGCATTGTCTAATTGAACATTCGAGAATGGCAATGCTTTTTGTGCAAGAAGGAGGTGTATATTTTGA
AGGCGGACACAATAATAGAG

Downstream 100 bases:

>100_bases
GATTACGATGGATTGGAGAAATGTGTGATGATTAATCATTTGATTAACGAACTGGTAAATTATGGATTGAAAAACGGTCT
GATTGATCTTGCAGATGAGG

Product: galactokinase

Products: NA

Alternate protein names: Galactose kinase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MINGRMCDDVLTDIYVDKDKLPYERKRYIEAIEQYITRFGDDDVWIYSAPGRSEIGGNHTDHQHGEVLAASINHDAIAVA
KKLDDQVVRIVSDGYNNLIAIHLDDLDKKDKEEGSTQALIRGVLAKTKENGHTIGGFQAYITSDVLIGAGLSSSAAFETL
IGTILSYMYNQGNISAIEIAMIGQYAENVYFGKPCGLMDQMACSVGSLVHINFENPQKPEVERVEFDLDVHGYSLCITDT
KGSHADLTPDYAAIPMEMKQAAACFGKEVLGEVSKKEILSNLSKIRAEAGDRAALRALHFICENERVQKEVDALKKDNFS
EFLLLVKKSGDSSFKYLQNVFTCHDVSHQNVSVALAVSEILLEDKGVCRVHGGGFAGTIQAFVPNELVEHYKTGMEEVFG
SGACDVLKIRKYGGIKVI

Sequences:

>Translated_418_residues
MINGRMCDDVLTDIYVDKDKLPYERKRYIEAIEQYITRFGDDDVWIYSAPGRSEIGGNHTDHQHGEVLAASINHDAIAVA
KKLDDQVVRIVSDGYNNLIAIHLDDLDKKDKEEGSTQALIRGVLAKTKENGHTIGGFQAYITSDVLIGAGLSSSAAFETL
IGTILSYMYNQGNISAIEIAMIGQYAENVYFGKPCGLMDQMACSVGSLVHINFENPQKPEVERVEFDLDVHGYSLCITDT
KGSHADLTPDYAAIPMEMKQAAACFGKEVLGEVSKKEILSNLSKIRAEAGDRAALRALHFICENERVQKEVDALKKDNFS
EFLLLVKKSGDSSFKYLQNVFTCHDVSHQNVSVALAVSEILLEDKGVCRVHGGGFAGTIQAFVPNELVEHYKTGMEEVFG
SGACDVLKIRKYGGIKVI
>Mature_418_residues
MINGRMCDDVLTDIYVDKDKLPYERKRYIEAIEQYITRFGDDDVWIYSAPGRSEIGGNHTDHQHGEVLAASINHDAIAVA
KKLDDQVVRIVSDGYNNLIAIHLDDLDKKDKEEGSTQALIRGVLAKTKENGHTIGGFQAYITSDVLIGAGLSSSAAFETL
IGTILSYMYNQGNISAIEIAMIGQYAENVYFGKPCGLMDQMACSVGSLVHINFENPQKPEVERVEFDLDVHGYSLCITDT
KGSHADLTPDYAAIPMEMKQAAACFGKEVLGEVSKKEILSNLSKIRAEAGDRAALRALHFICENERVQKEVDALKKDNFS
EFLLLVKKSGDSSFKYLQNVFTCHDVSHQNVSVALAVSEILLEDKGVCRVHGGGFAGTIQAFVPNELVEHYKTGMEEVFG
SGACDVLKIRKYGGIKVI

Specific function: Galactose metabolism; first step. [C]

COG id: COG0153

COG function: function code G; Galactokinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. GalK subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503895, Length=384, Percent_Identity=27.34375, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1786972, Length=387, Percent_Identity=26.8733850129199, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000705
- InterPro:   IPR022963
- InterPro:   IPR019741
- InterPro:   IPR019539
- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006206
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF10509 GalKase_gal_bdg; PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.6 [H]

Molecular weight: Translated: 45970; Mature: 45970

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINGRMCDDVLTDIYVDKDKLPYERKRYIEAIEQYITRFGDDDVWIYSAPGRSEIGGNHT
CCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
DHQHGEVLAASINHDAIAVAKKLDDQVVRIVSDGYNNLIAIHLDDLDKKDKEEGSTQALI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHCCHHHHHH
RGVLAKTKENGHTIGGFQAYITSDVLIGAGLSSSAAFETLIGTILSYMYNQGNISAIEIA
HHHHHHHCCCCCEECCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
MIGQYAENVYFGKPCGLMDQMACSVGSLVHINFENPQKPEVERVEFDLDVHGYSLCITDT
EHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEECCEEEEEECC
KGSHADLTPDYAAIPMEMKQAAACFGKEVLGEVSKKEILSNLSKIRAEAGDRAALRALHF
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ICENERVQKEVDALKKDNFSEFLLLVKKSGDSSFKYLQNVFTCHDVSHQNVSVALAVSEI
HHCCHHHHHHHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHH
LLEDKGVCRVHGGGFAGTIQAFVPNELVEHYKTGMEEVFGSGACDVLKIRKYGGIKVI
HHCCCCEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEC
>Mature Secondary Structure
MINGRMCDDVLTDIYVDKDKLPYERKRYIEAIEQYITRFGDDDVWIYSAPGRSEIGGNHT
CCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
DHQHGEVLAASINHDAIAVAKKLDDQVVRIVSDGYNNLIAIHLDDLDKKDKEEGSTQALI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHCCHHHHHH
RGVLAKTKENGHTIGGFQAYITSDVLIGAGLSSSAAFETLIGTILSYMYNQGNISAIEIA
HHHHHHHCCCCCEECCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
MIGQYAENVYFGKPCGLMDQMACSVGSLVHINFENPQKPEVERVEFDLDVHGYSLCITDT
EHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEECCEEEEEECC
KGSHADLTPDYAAIPMEMKQAAACFGKEVLGEVSKKEILSNLSKIRAEAGDRAALRALHF
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ICENERVQKEVDALKKDNFSEFLLLVKKSGDSSFKYLQNVFTCHDVSHQNVSVALAVSEI
HHCCHHHHHHHHHHHCCCHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHH
LLEDKGVCRVHGGGFAGTIQAFVPNELVEHYKTGMEEVFGSGACDVLKIRKYGGIKVI
HHCCCCEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA