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The map label for this gene is prc [C]

Identifier: 238917730

GI number: 238917730

Start: 1871893

End: 1873185

Strand: Reverse

Name: prc [C]

Synonym: EUBELI_01810

Alternate gene names: 238917730

Gene position: 1873185-1871893 (Counterclockwise)

Preceding gene: 238917731

Following gene: 238917729

Centisome position: 87.36

GC content: 40.68

Gene sequence:

>1293_bases
ATGGAATATGATAATAACAGACCTTTTTCTTCGGAAGGGGCCGCACAGGAACGAAAGAGAAAACATGCTTTAGGCAAAGG
CGTTATTATTGGTGTTGTGGCAACACTGCTGGTTGTGATACTGGCGTTGTCATGCGTATTCATGGGACTTATAAGAAGTG
GTAATCTTCATATTGGAATTGACGGACGTATATATGTCCAGGATGTTGGAACAAGTGATAATGAAGGAATCGGAACTAAG
GTTGAAGGTAAGCTGAATGCTTTGGATTCGCTGCTTGGAGATGGATTCTACTTTGATGATGTAGATGATGAAAAGGCTGC
AGACAACATTTTTAAGGCATATCTTGCTGCATATGGTGATAAATATACTGTTTATTATACGCCTGAAGAATATAAGTCAA
TGATGGAGTCAACATCAGGTTCTTTCTATGGAATTGGTGCTGTATGCCAGAAGGCTGACGACGGTTCAATACTTATATCA
GAGGCATATGAGGATGCACCGGCATATAAGGCTGGTATCAGAAATGGAGATAAGGTAACAGAGGTTAATGGTGAGGATAT
TACAGGAATGGACCTTTCTGTAGCAGTTGCCCTTATTAAGGGCGAGAAGGGTACAGATGTTAACCTTACTGTTATGAGAA
ATGGCGAGAAGCTGAGTTTCACAGTTACAAGAGACAAGATTGATATTAAGACTGTTTCATCAGAGGTGCTTGAGAATAAT
ATAGGTTATATTTATATTTCGCAGTTTGATGATGTTACAACAGAGCAGTTTAAATCGGCTGTTGATGACCTTCAGAAGCA
GGGAATTACAGGACTTGTAATTGATATAAGAAATAATCCTGGCGGAGTTCTTAAGACTGTGGCTGATATGCTAGATTATA
TTCTTCCGAACGGACTTATCGTGTATACAGAGACTAAGTCTGGTAAGAGACAGGAATATTCAGGTTCTGATAATCATGAG
CTTAATATTCCGATGGCAGTTTTGGTAAATGGCAATAGTGCAAGTGCATCTGAGATATTTGCCGGTGCAATGCAGGATTA
TGATAAGGCACAGATAATCGGAACACAGACATTTGGTAAGGGTATTGTGCAGACAATCCGTCCGCTTACTGATGGAAGTG
CAGTTAAGTATACAATTGCCAAATATTTTACTCCTAAGGGACAGGATATTCACGGCAAGGGAGTGACACCAGACAGTATT
GTGGAGCTTCCGGATGATGCGACTGAAGATGTGCAGTTGAAGGCAGCAGTAGAGTATCTCAATGGGAAAATGAGTGTCAG
CGCGGCAGAATAA

Upstream 100 bases:

>100_bases
CATTTGGCGCACATCTGCATTTTGATGTAAGGCTCAATGATTCATATGTTAATCCTATGCCATATTTTAAATAAATAATT
CAACTTAATAGGAGGACTCA

Downstream 100 bases:

>100_bases
AGATTATAGAAGTATGGAATAAAGTACAGGACAAATCGAATGTTTGTTCTGTACTTTTTGGCTGTTATATTGTATAATGA
GAAAAATGTTGGAAAACAAG

Product: carboxyl-terminal processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MEYDNNRPFSSEGAAQERKRKHALGKGVIIGVVATLLVVILALSCVFMGLIRSGNLHIGIDGRIYVQDVGTSDNEGIGTK
VEGKLNALDSLLGDGFYFDDVDDEKAADNIFKAYLAAYGDKYTVYYTPEEYKSMMESTSGSFYGIGAVCQKADDGSILIS
EAYEDAPAYKAGIRNGDKVTEVNGEDITGMDLSVAVALIKGEKGTDVNLTVMRNGEKLSFTVTRDKIDIKTVSSEVLENN
IGYIYISQFDDVTTEQFKSAVDDLQKQGITGLVIDIRNNPGGVLKTVADMLDYILPNGLIVYTETKSGKRQEYSGSDNHE
LNIPMAVLVNGNSASASEIFAGAMQDYDKAQIIGTQTFGKGIVQTIRPLTDGSAVKYTIAKYFTPKGQDIHGKGVTPDSI
VELPDDATEDVQLKAAVEYLNGKMSVSAAE

Sequences:

>Translated_430_residues
MEYDNNRPFSSEGAAQERKRKHALGKGVIIGVVATLLVVILALSCVFMGLIRSGNLHIGIDGRIYVQDVGTSDNEGIGTK
VEGKLNALDSLLGDGFYFDDVDDEKAADNIFKAYLAAYGDKYTVYYTPEEYKSMMESTSGSFYGIGAVCQKADDGSILIS
EAYEDAPAYKAGIRNGDKVTEVNGEDITGMDLSVAVALIKGEKGTDVNLTVMRNGEKLSFTVTRDKIDIKTVSSEVLENN
IGYIYISQFDDVTTEQFKSAVDDLQKQGITGLVIDIRNNPGGVLKTVADMLDYILPNGLIVYTETKSGKRQEYSGSDNHE
LNIPMAVLVNGNSASASEIFAGAMQDYDKAQIIGTQTFGKGIVQTIRPLTDGSAVKYTIAKYFTPKGQDIHGKGVTPDSI
VELPDDATEDVQLKAAVEYLNGKMSVSAAE
>Mature_430_residues
MEYDNNRPFSSEGAAQERKRKHALGKGVIIGVVATLLVVILALSCVFMGLIRSGNLHIGIDGRIYVQDVGTSDNEGIGTK
VEGKLNALDSLLGDGFYFDDVDDEKAADNIFKAYLAAYGDKYTVYYTPEEYKSMMESTSGSFYGIGAVCQKADDGSILIS
EAYEDAPAYKAGIRNGDKVTEVNGEDITGMDLSVAVALIKGEKGTDVNLTVMRNGEKLSFTVTRDKIDIKTVSSEVLENN
IGYIYISQFDDVTTEQFKSAVDDLQKQGITGLVIDIRNNPGGVLKTVADMLDYILPNGLIVYTETKSGKRQEYSGSDNHE
LNIPMAVLVNGNSASASEIFAGAMQDYDKAQIIGTQTFGKGIVQTIRPLTDGSAVKYTIAKYFTPKGQDIHGKGVTPDSI
VELPDDATEDVQLKAAVEYLNGKMSVSAAE

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=337, Percent_Identity=34.1246290801187, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 46410; Mature: 46410

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYDNNRPFSSEGAAQERKRKHALGKGVIIGVVATLLVVILALSCVFMGLIRSGNLHIGI
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DGRIYVQDVGTSDNEGIGTKVEGKLNALDSLLGDGFYFDDVDDEKAADNIFKAYLAAYGD
CCEEEEEECCCCCCCCCCCEECCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCC
KYTVYYTPEEYKSMMESTSGSFYGIGAVCQKADDGSILISEAYEDAPAYKAGIRNGDKVT
CEEEEECCHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEECCCCCCCCHHHHCCCCCEEE
EVNGEDITGMDLSVAVALIKGEKGTDVNLTVMRNGEKLSFTVTRDKIDIKTVSSEVLENN
ECCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEEEECCEEEEHHHHHHHHHCC
IGYIYISQFDDVTTEQFKSAVDDLQKQGITGLVIDIRNNPGGVLKTVADMLDYILPNGLI
CCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEE
VYTETKSGKRQEYSGSDNHELNIPMAVLVNGNSASASEIFAGAMQDYDKAQIIGTQTFGK
EEEECCCCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECHHHHH
GIVQTIRPLTDGSAVKYTIAKYFTPKGQDIHGKGVTPDSIVELPDDATEDVQLKAAVEYL
HHHHHHHCCCCCCEEEEEEEEHCCCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHH
NGKMSVSAAE
CCCEEEEECC
>Mature Secondary Structure
MEYDNNRPFSSEGAAQERKRKHALGKGVIIGVVATLLVVILALSCVFMGLIRSGNLHIGI
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DGRIYVQDVGTSDNEGIGTKVEGKLNALDSLLGDGFYFDDVDDEKAADNIFKAYLAAYGD
CCEEEEEECCCCCCCCCCCEECCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCC
KYTVYYTPEEYKSMMESTSGSFYGIGAVCQKADDGSILISEAYEDAPAYKAGIRNGDKVT
CEEEEECCHHHHHHHHHCCCCEEEEHHHHCCCCCCCEEEECCCCCCCCHHHHCCCCCEEE
EVNGEDITGMDLSVAVALIKGEKGTDVNLTVMRNGEKLSFTVTRDKIDIKTVSSEVLENN
ECCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEEEECCEEEEHHHHHHHHHCC
IGYIYISQFDDVTTEQFKSAVDDLQKQGITGLVIDIRNNPGGVLKTVADMLDYILPNGLI
CCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEE
VYTETKSGKRQEYSGSDNHELNIPMAVLVNGNSASASEIFAGAMQDYDKAQIIGTQTFGK
EEEECCCCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECHHHHH
GIVQTIRPLTDGSAVKYTIAKYFTPKGQDIHGKGVTPDSIVELPDDATEDVQLKAAVEYL
HHHHHHHCCCCCCEEEEEEEEHCCCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHH
NGKMSVSAAE
CCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA