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The map label for this gene is yycF [H]

Identifier: 238917445

GI number: 238917445

Start: 1578317

End: 1579006

Strand: Reverse

Name: yycF [H]

Synonym: EUBELI_01523

Alternate gene names: 238917445

Gene position: 1579006-1578317 (Counterclockwise)

Preceding gene: 238917446

Following gene: 238917444

Centisome position: 73.64

GC content: 37.97

Gene sequence:

>690_bases
ATGCCAGGTATACTCGTGGTTGAAGATGATGAAAATTTAAATCGTGGAATTACATTTTCACTGAAAAAATCCGGATATGA
GGTTTTTTCAGCAGAATCAGTGAAAAAAGCAAAAAGAATTGCAAGTGATAATAATGTGGATGTTACCATTTGTGATGTGA
ATCTTCCGGATGGGAATGGACTGGAATTTGTAAGGTGGATGAGATGCAATTATAATACATACATTATCTGTCTTACAGCA
CTAGATCAGGAGATGGATCAGGTCATGGGATATGAAGCAGGGGCAGATGATTATATTACCAAGCCGTTTAGTCTTTCGGT
ACTTCTTTTGAAAATAGAAGCACATTTCCGTCGCAGACAGGAGAAAACGGAAGCCGGAAAGATGATTTCGGGAGATATCG
TATTTATTGCAGAAGAAATGAAAGTCCTGATAAAGAGTCGTGAAATCAGTCTGACAAAAACGGAGTTGAAAATGCTGACT
TTTTTTCTTCAGAATCCGAAACAGATTCTTTCAAGAACACAAATATTGGAAAATGTGTTTGATCTGGAAGGGGATTTTGT
GGATGAAAATACAATCGCTGTCAATATCAGAAGACTCCGTGAGAAAATTGAAGACAATCCGGCTGCACCGGTCTATATAA
AGAATATCAGAGGTCTTGGGTATATATGGAATCAGGAGGTAAGGCAGTGA

Upstream 100 bases:

>100_bases
TATAACATCTGCAGAGACTAAGGCTACATATGGAGAGGGCAATTGTGGAGGCATTGAAGCATTTTAAGATGAATAGTTAA
TAAAGAGAGGTGCATATGCT

Downstream 100 bases:

>100_bases
CAAAGAGATATCGCAAGAAGATTACAGTAGTGCTCTCCTTGGTGGTGCCTGTCATAGTATTGTTTGCAATATTAAATTGC
TTTACCACATATGTGTTTTA

Product: two-component system OmpR family phosphate regulon response regulator OmpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPGILVVEDDENLNRGITFSLKKSGYEVFSAESVKKAKRIASDNNVDVTICDVNLPDGNGLEFVRWMRCNYNTYIICLTA
LDQEMDQVMGYEAGADDYITKPFSLSVLLLKIEAHFRRRQEKTEAGKMISGDIVFIAEEMKVLIKSREISLTKTELKMLT
FFLQNPKQILSRTQILENVFDLEGDFVDENTIAVNIRRLREKIEDNPAAPVYIKNIRGLGYIWNQEVRQ

Sequences:

>Translated_229_residues
MPGILVVEDDENLNRGITFSLKKSGYEVFSAESVKKAKRIASDNNVDVTICDVNLPDGNGLEFVRWMRCNYNTYIICLTA
LDQEMDQVMGYEAGADDYITKPFSLSVLLLKIEAHFRRRQEKTEAGKMISGDIVFIAEEMKVLIKSREISLTKTELKMLT
FFLQNPKQILSRTQILENVFDLEGDFVDENTIAVNIRRLREKIEDNPAAPVYIKNIRGLGYIWNQEVRQ
>Mature_228_residues
PGILVVEDDENLNRGITFSLKKSGYEVFSAESVKKAKRIASDNNVDVTICDVNLPDGNGLEFVRWMRCNYNTYIICLTAL
DQEMDQVMGYEAGADDYITKPFSLSVLLLKIEAHFRRRQEKTEAGKMISGDIVFIAEEMKVLIKSREISLTKTELKMLTF
FLQNPKQILSRTQILENVFDLEGDFVDENTIAVNIRRLREKIEDNPAAPVYIKNIRGLGYIWNQEVRQ

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=30.3571428571429, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=34.5454545454545, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.6742081447964, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.7017543859649, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=32.1100917431193, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=28.6363636363636, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=27.3127753303965, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=210, Percent_Identity=30.4761904761905, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=28.9473684210526, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=26.3392857142857, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=28.8288288288288, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=28.3842794759825, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=28.6324786324786, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=28.6885245901639, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26281; Mature: 26149

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGILVVEDDENLNRGITFSLKKSGYEVFSAESVKKAKRIASDNNVDVTICDVNLPDGNG
CCCEEEEECCCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
LEFVRWMRCNYNTYIICLTALDQEMDQVMGYEAGADDYITKPFSLSVLLLKIEAHFRRRQ
CCEEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEEEHHHHHHHHH
EKTEAGKMISGDIVFIAEEMKVLIKSREISLTKTELKMLTFFLQNPKQILSRTQILENVF
HHHHHCCEECCCEEEEHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DLEGDFVDENTIAVNIRRLREKIEDNPAAPVYIKNIRGLGYIWNQEVRQ
HCCCCEECCCEEEEEHHHHHHHHHCCCCCCEEEECCCCCCEEHHHHHCC
>Mature Secondary Structure 
PGILVVEDDENLNRGITFSLKKSGYEVFSAESVKKAKRIASDNNVDVTICDVNLPDGNG
CCEEEEECCCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
LEFVRWMRCNYNTYIICLTALDQEMDQVMGYEAGADDYITKPFSLSVLLLKIEAHFRRRQ
CCEEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEEEHHHHHHHHH
EKTEAGKMISGDIVFIAEEMKVLIKSREISLTKTELKMLTFFLQNPKQILSRTQILENVF
HHHHHCCEECCCEEEEHHHHHHHHHHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DLEGDFVDENTIAVNIRRLREKIEDNPAAPVYIKNIRGLGYIWNQEVRQ
HCCCCEECCCEEEEEHHHHHHHHHCCCCCCEEEECCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]