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The map label for this gene is ndhS [H]

Identifier: 238917416

GI number: 238917416

Start: 1551306

End: 1551773

Strand: Reverse

Name: ndhS [H]

Synonym: EUBELI_01494

Alternate gene names: 238917416

Gene position: 1551773-1551306 (Counterclockwise)

Preceding gene: 238917417

Following gene: 238917415

Centisome position: 72.37

GC content: 40.38

Gene sequence:

>468_bases
ATGTTAGTTGATATTAAGTTGAATGGAAAATCTGTTAAAGCAGATATTACGGCAGACATGACACTCTATGAATTCGTGAG
AGAGCATGGCTGTTACAGCGTAAAATGTGGCTGTGAAACATCTAACTGTGGCTTATGTACAGTATTTCTTAATGATAAGC
CTGTCCTTTCATGTTCAGTTCTTGCAGCAAGAGCAGACAAATGCAGTGTTACAACACTCGAAGGATTACAGGAGGAGGCG
TCTGAATTTGTCACATTTATAGCAGATCAGGGAGCAGAGCAGTGTGGATTCTGTAATCCGGGATTTGTTATGAATGCATT
GGCACTTTTCAGAGAGAATCCTTATCCTGATGAAGAGGAGATAAAGGAGTTCCTTTCAGGAAATCTGTGCAGATGTTCAG
GTTATGAGGGACAGTTAAGAGGAATTATGAATTTCCTTGAGGCAAAGAAAGCAAAGGAGGCTGAATAG

Upstream 100 bases:

>100_bases
GGAAGTGCTGAGTATAGAAGTCATCTTTCAGGCGTTCTTGCAGGCAGGGCACTTCAGAATATTAACAGAGATTAATTGGT
GATTACGGATTGGAGAATAT

Downstream 100 bases:

>100_bases
ATGAAGTCGGTTAATAAAGCTATCAGAAAGAAAGATGCGATGGAACTGCTTCTTGGAAAGCCGGTGTATACAGATGATAT
TGCACCTAAGGACTGCCTTG

Product: carbon-monoxide dehydrogenase small subunit

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase small FeS subunit; NAH [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MLVDIKLNGKSVKADITADMTLYEFVREHGCYSVKCGCETSNCGLCTVFLNDKPVLSCSVLAARADKCSVTTLEGLQEEA
SEFVTFIADQGAEQCGFCNPGFVMNALALFRENPYPDEEEIKEFLSGNLCRCSGYEGQLRGIMNFLEAKKAKEAE

Sequences:

>Translated_155_residues
MLVDIKLNGKSVKADITADMTLYEFVREHGCYSVKCGCETSNCGLCTVFLNDKPVLSCSVLAARADKCSVTTLEGLQEEA
SEFVTFIADQGAEQCGFCNPGFVMNALALFRENPYPDEEEIKEFLSGNLCRCSGYEGQLRGIMNFLEAKKAKEAE
>Mature_155_residues
MLVDIKLNGKSVKADITADMTLYEFVREHGCYSVKCGCETSNCGLCTVFLNDKPVLSCSVLAARADKCSVTTLEGLQEEA
SEFVTFIADQGAEQCGFCNPGFVMNALALFRENPYPDEEEIKEFLSGNLCRCSGYEGQLRGIMNFLEAKKAKEAE

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=35.0649350649351, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=38.2978723404255, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.2549019607843, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=34.1935483870968, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737937, Length=155, Percent_Identity=34.1935483870968, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=147, Percent_Identity=31.9727891156463, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647195, Length=147, Percent_Identity=31.9727891156463, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=31.2101910828025, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=31.2101910828025, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 17024; Mature: 17024

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
7.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDIKLNGKSVKADITADMTLYEFVREHGCYSVKCGCETSNCGLCTVFLNDKPVLSCSV
CEEEEEECCCEEEEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCEEHHH
LAARADKCSVTTLEGLQEEASEFVTFIADQGAEQCGFCNPGFVMNALALFRENPYPDEEE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
IKEFLSGNLCRCSGYEGQLRGIMNFLEAKKAKEAE
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLVDIKLNGKSVKADITADMTLYEFVREHGCYSVKCGCETSNCGLCTVFLNDKPVLSCSV
CEEEEEECCCEEEEEEEHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCEEHHH
LAARADKCSVTTLEGLQEEASEFVTFIADQGAEQCGFCNPGFVMNALALFRENPYPDEEE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
IKEFLSGNLCRCSGYEGQLRGIMNFLEAKKAKEAE
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA