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The map label for this gene is nadA [H]

Identifier: 238917354

GI number: 238917354

Start: 1485437

End: 1486342

Strand: Reverse

Name: nadA [H]

Synonym: EUBELI_01431

Alternate gene names: 238917354

Gene position: 1486342-1485437 (Counterclockwise)

Preceding gene: 238917355

Following gene: 238917353

Centisome position: 69.32

GC content: 37.31

Gene sequence:

>906_bases
ATGTCAGTTACAAGTGATATTTTAAAGTTGAAAAAAGAGAAGAATGCAGTTATTCTTGCACATTATTATGTAGATGAAGA
TGTTCAGGAAGTTGCTGATTATGTCGGGGATTCATTCTATCTTAGCAAGGTAGCTACTAAGGTAGATCAGGATATTATAG
TATTTGCGGGTGTTGAGTTCATGGGTGAGAGTGCTAAGATTCTTAATCCGGAAAAGAAGGTGCTTATGCCAGAGCCGGGG
GCTGATTGTCCAATGGCACATATGGCAACTAAGGAAGAAATTTTTAAGATGCGTGAACAGTATGATGACCTTGCAGTTGT
CTGTTACATCAATTCAACAGCAGAGCTAAAGACTTATTCAGACGTCTGTGTGACATCATCAAATGCAGTAAAGATAGTAA
AGAACCTTCCTAATAAAAACATCTTCTTTATTCCTGATCAGAATCTTGGAAGATTCGTTGCAAAGCAGGTGCCAGAGAAA
AATGTGATTCTTAATAAAGGCTTCTGTCCAAGACATGTCGCGATAACAGAGAATATGGTCGTTGAAATTAAGAAGAAATA
TCCACAGGCAAAGCTTGCAGCACACCCTGAATGTACAGAGGAAGTATTAAAATATGCTGATTACATAGGCAGTACATCAG
GAATTATTGATTATGTTGTAGATACAGATTGTGAGGAATTCATAATTGCAACAGTTGATGGTGTATTTGGTGAGATAAGA
AAAAAGGCACCTGGCAAGAAACTGTATACATTAAAGCCTGACCAGGTATGTGTCAACATGAAGATGGTAACCTTAGATAA
GGTGCTTGATGTTCTTGAACAGGAAAATAATGAAGTGTTTGTAGATGAAGAAGTTGCAAAGAAAGCAATGAAGCCACTTA
CAAGAATGCTTGAGCTTGCAAAATAA

Upstream 100 bases:

>100_bases
CAACTGTCTTGTCACATGTAAACATTCGTGGTATACTCTAGCACAATGTATGTAAAACGCAAGTCAAGCATATGTAAACC
TTAACGATTGGAGAAGCAAT

Downstream 100 bases:

>100_bases
GATTGTAGTATGCGCAGAAAGAATGGAGGTATCCTATGAATAATACAATTAAAACAGATGTGCTGATAGCCGGATGTGGC
TGTTCTGGTCTGTATATGGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSVTSDILKLKKEKNAVILAHYYVDEDVQEVADYVGDSFYLSKVATKVDQDIIVFAGVEFMGESAKILNPEKKVLMPEPG
ADCPMAHMATKEEIFKMREQYDDLAVVCYINSTAELKTYSDVCVTSSNAVKIVKNLPNKNIFFIPDQNLGRFVAKQVPEK
NVILNKGFCPRHVAITENMVVEIKKKYPQAKLAAHPECTEEVLKYADYIGSTSGIIDYVVDTDCEEFIIATVDGVFGEIR
KKAPGKKLYTLKPDQVCVNMKMVTLDKVLDVLEQENNEVFVDEEVAKKAMKPLTRMLELAK

Sequences:

>Translated_301_residues
MSVTSDILKLKKEKNAVILAHYYVDEDVQEVADYVGDSFYLSKVATKVDQDIIVFAGVEFMGESAKILNPEKKVLMPEPG
ADCPMAHMATKEEIFKMREQYDDLAVVCYINSTAELKTYSDVCVTSSNAVKIVKNLPNKNIFFIPDQNLGRFVAKQVPEK
NVILNKGFCPRHVAITENMVVEIKKKYPQAKLAAHPECTEEVLKYADYIGSTSGIIDYVVDTDCEEFIIATVDGVFGEIR
KKAPGKKLYTLKPDQVCVNMKMVTLDKVLDVLEQENNEVFVDEEVAKKAMKPLTRMLELAK
>Mature_300_residues
SVTSDILKLKKEKNAVILAHYYVDEDVQEVADYVGDSFYLSKVATKVDQDIIVFAGVEFMGESAKILNPEKKVLMPEPGA
DCPMAHMATKEEIFKMREQYDDLAVVCYINSTAELKTYSDVCVTSSNAVKIVKNLPNKNIFFIPDQNLGRFVAKQVPEKN
VILNKGFCPRHVAITENMVVEIKKKYPQAKLAAHPECTEEVLKYADYIGSTSGIIDYVVDTDCEEFIIATVDGVFGEIRK
KAPGKKLYTLKPDQVCVNMKMVTLDKVLDVLEQENNEVFVDEEVAKKAMKPLTRMLELAK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=35.048231511254, Blast_Score=187, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 33838; Mature: 33706

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSDILKLKKEKNAVILAHYYVDEDVQEVADYVGDSFYLSKVATKVDQDIIVFAGVEF
CCCHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECHHH
MGESAKILNPEKKVLMPEPGADCPMAHMATKEEIFKMREQYDDLAVVCYINSTAELKTYS
HCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEECC
DVCVTSSNAVKIVKNLPNKNIFFIPDQNLGRFVAKQVPEKNVILNKGFCPRHVAITENMV
HHEEECCCHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCHHH
VEIKKKYPQAKLAAHPECTEEVLKYADYIGSTSGIIDYVVDTDCEEFIIATVDGVFGEIR
HHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KKAPGKKLYTLKPDQVCVNMKMVTLDKVLDVLEQENNEVFVDEEVAKKAMKPLTRMLELA
HCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure 
SVTSDILKLKKEKNAVILAHYYVDEDVQEVADYVGDSFYLSKVATKVDQDIIVFAGVEF
CCHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECHHH
MGESAKILNPEKKVLMPEPGADCPMAHMATKEEIFKMREQYDDLAVVCYINSTAELKTYS
HCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEECC
DVCVTSSNAVKIVKNLPNKNIFFIPDQNLGRFVAKQVPEKNVILNKGFCPRHVAITENMV
HHEEECCCHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCHHH
VEIKKKYPQAKLAAHPECTEEVLKYADYIGSTSGIIDYVVDTDCEEFIIATVDGVFGEIR
HHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KKAPGKKLYTLKPDQVCVNMKMVTLDKVLDVLEQENNEVFVDEEVAKKAMKPLTRMLELA
HCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]