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The map label for this gene is speA [H]

Identifier: 238917349

GI number: 238917349

Start: 1479477

End: 1480931

Strand: Reverse

Name: speA [H]

Synonym: EUBELI_01426

Alternate gene names: 238917349

Gene position: 1480931-1479477 (Counterclockwise)

Preceding gene: 238917350

Following gene: 238917348

Centisome position: 69.07

GC content: 41.24

Gene sequence:

>1455_bases
ATGGACTTAAAAAGACAGGCGAGTGCGCCGCTTTACGAAGCAATTGAGAAATTCAGAAAGAAAAGAATTGTTCCGTTTGA
TGTTCCGGGACATAAGAGAGGAAGAGGCAACCCAGAACTGGTAGATTTACTTGGAGAAAGATGTGTTGGAATAGATGTTA
ATTCAATGAAGCCACTTGATAACCTGTGCCACCCTGTTTCTGTTATTAAGGAGGCAGAGGAGCTCACAGCAGAGGCATTT
GGGGCAGAACACGCATTTTTCATGGTAGGAGGAACTACGCAGGCAGTACAGAACATGGTGTTATCTGTATGTAAGGCTGG
AGATGAGATTATCGTTCCAAGAAATGTGCATAAAAGCGTAATTAATGCATTGATTCTGTGTGGTGCGATTCCTGTTTATC
TTAATACAGAAATTAATGCAAAGCTTGGAATAGTGCTTGGAGTAACTGTGCAGCAGGTTGAAAAGACAATACAGGAGCAT
CCGAATGCGGTGGCGGTTTTGGTGAATAATCCTACATATTATGGAATCTGTTCAGACATTAAAGGAATATGTGATATAGC
ACATTCATATGGACTTAAGGTGCTTGCCGATGAGGCACATGGAACGCATCTGTATTTTGGTGACAACCTTCCTATGAATT
CAATGAAAGCAGGAGCAGACCTTGCAGCAATATCAATGCATAAGTCAGGCGGTTCGCTTACGCAGAGTTCGATCCTTCTT
ACCAATAATGGTATGAATGCTGATTATGTACAGACAATTATTAATATTACGCAGACAACGAGCGCGTCATATCTTCTTAT
GACAAGCCTTGATATATCAAGAAGAAATCTTGCCCTGCGCGGCAGACAGTCATTTGCAAAGGTGAGCGAGTGGGCACAGT
ATGCAAGAGATGAGATTAATATGGTAGGGGGTTATTATGCATACGGAAAAGAACTGATTAATGGTGGAACAGTCTATGAT
TATGATGTTACCAAGCTTTGTGTTTATACAAGGGATATCGGACTTGATGGAATTGAGGTGTATGATATCTTAAGAGATGA
GTATGATATCCAGATAGAATTCGGCGACATTGGAAATATAATGGCGTACATATCAATTGGTGACAGAATACAGGATATAG
AAAGACTTGTCGGAGCATTGGCTGAAATCAGCCGTCTGTATTCAAAAGAAGAAAAACGCTTTGAAGTAGACAGACAAATG
CTGCTTCCAAGGGTACTTGCTTCACCACAGGAAGCCTTCTATGCCGATAAGATTAAAGTTCCAATCCGTGAGGCAGCAGG
ACATATATCAGGGGAGTTCGTAATGGCATATCCGCCAGGAATTCCTATACTTGCGCCGGGTGAAGAAATCACAGACGAGA
TAATAGACTATATTCAGTATTCAGTAGAGAAGGGCTGTTCAATGCAGGGAATGGAAGATTCAACATTGCAGACACTGAAT
GTATTAAGAATGTAA

Upstream 100 bases:

>100_bases
GGATTTCTTCACGGATATTCGAGGAGCGCCGCGACAATGACAGAGCGAAGCTCTGGAATAAAGCTGCGAGCGCGAGCAGC
GATGAGAACAGGGGGAGATT

Downstream 100 bases:

>100_bases
ATGTCCGATTTGTTCAATCGGTCAAATATAGAAGGGAGAAAGTTTCTATGGAATTTTGGTTTTCAGAACTTCATTCACCA
CATGTGAAGTTTGATATCAG

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MDLKRQASAPLYEAIEKFRKKRIVPFDVPGHKRGRGNPELVDLLGERCVGIDVNSMKPLDNLCHPVSVIKEAEELTAEAF
GAEHAFFMVGGTTQAVQNMVLSVCKAGDEIIVPRNVHKSVINALILCGAIPVYLNTEINAKLGIVLGVTVQQVEKTIQEH
PNAVAVLVNNPTYYGICSDIKGICDIAHSYGLKVLADEAHGTHLYFGDNLPMNSMKAGADLAAISMHKSGGSLTQSSILL
TNNGMNADYVQTIINITQTTSASYLLMTSLDISRRNLALRGRQSFAKVSEWAQYARDEINMVGGYYAYGKELINGGTVYD
YDVTKLCVYTRDIGLDGIEVYDILRDEYDIQIEFGDIGNIMAYISIGDRIQDIERLVGALAEISRLYSKEEKRFEVDRQM
LLPRVLASPQEAFYADKIKVPIREAAGHISGEFVMAYPPGIPILAPGEEITDEIIDYIQYSVEKGCSMQGMEDSTLQTLN
VLRM

Sequences:

>Translated_484_residues
MDLKRQASAPLYEAIEKFRKKRIVPFDVPGHKRGRGNPELVDLLGERCVGIDVNSMKPLDNLCHPVSVIKEAEELTAEAF
GAEHAFFMVGGTTQAVQNMVLSVCKAGDEIIVPRNVHKSVINALILCGAIPVYLNTEINAKLGIVLGVTVQQVEKTIQEH
PNAVAVLVNNPTYYGICSDIKGICDIAHSYGLKVLADEAHGTHLYFGDNLPMNSMKAGADLAAISMHKSGGSLTQSSILL
TNNGMNADYVQTIINITQTTSASYLLMTSLDISRRNLALRGRQSFAKVSEWAQYARDEINMVGGYYAYGKELINGGTVYD
YDVTKLCVYTRDIGLDGIEVYDILRDEYDIQIEFGDIGNIMAYISIGDRIQDIERLVGALAEISRLYSKEEKRFEVDRQM
LLPRVLASPQEAFYADKIKVPIREAAGHISGEFVMAYPPGIPILAPGEEITDEIIDYIQYSVEKGCSMQGMEDSTLQTLN
VLRM
>Mature_484_residues
MDLKRQASAPLYEAIEKFRKKRIVPFDVPGHKRGRGNPELVDLLGERCVGIDVNSMKPLDNLCHPVSVIKEAEELTAEAF
GAEHAFFMVGGTTQAVQNMVLSVCKAGDEIIVPRNVHKSVINALILCGAIPVYLNTEINAKLGIVLGVTVQQVEKTIQEH
PNAVAVLVNNPTYYGICSDIKGICDIAHSYGLKVLADEAHGTHLYFGDNLPMNSMKAGADLAAISMHKSGGSLTQSSILL
TNNGMNADYVQTIINITQTTSASYLLMTSLDISRRNLALRGRQSFAKVSEWAQYARDEINMVGGYYAYGKELINGGTVYD
YDVTKLCVYTRDIGLDGIEVYDILRDEYDIQIEFGDIGNIMAYISIGDRIQDIERLVGALAEISRLYSKEEKRFEVDRQM
LLPRVLASPQEAFYADKIKVPIREAAGHISGEFVMAYPPGIPILAPGEEITDEIIDYIQYSVEKGCSMQGMEDSTLQTLN
VLRM

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=313, Percent_Identity=24.6006389776358, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI221142684, Length=301, Percent_Identity=25.2491694352159, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790573, Length=283, Percent_Identity=23.321554770318, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53404; Mature: 53404

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKRQASAPLYEAIEKFRKKRIVPFDVPGHKRGRGNPELVDLLGERCVGIDVNSMKPLD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHCCEECCCCCCCCCHH
NLCHPVSVIKEAEELTAEAFGAEHAFFMVGGTTQAVQNMVLSVCKAGDEIIVPRNVHKSV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCHHHHHH
INALILCGAIPVYLNTEINAKLGIVLGVTVQQVEKTIQEHPNAVAVLVNNPTYYGICSDI
HHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEECCCEEEEEHHHH
KGICDIAHSYGLKVLADEAHGTHLYFGDNLPMNSMKAGADLAAISMHKSGGSLTQSSILL
HHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEE
TNNGMNADYVQTIINITQTTSASYLLMTSLDISRRNLALRGRQSFAKVSEWAQYARDEIN
ECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCHHHHHHHHHHHHHHHHHHH
MVGGYYAYGKELINGGTVYDYDVTKLCVYTRDIGLDGIEVYDILRDEYDIQIEFGDIGNI
HCCCHHHHHHHHHCCCEEEECCHHEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCE
MAYISIGDRIQDIERLVGALAEISRLYSKEEKRFEVDRQMLLPRVLASPQEAFYADKIKV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
PIREAAGHISGEFVMAYPPGIPILAPGEEITDEIIDYIQYSVEKGCSMQGMEDSTLQTLN
CHHHHCCCCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VLRM
HHCC
>Mature Secondary Structure
MDLKRQASAPLYEAIEKFRKKRIVPFDVPGHKRGRGNPELVDLLGERCVGIDVNSMKPLD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHCCEECCCCCCCCCHH
NLCHPVSVIKEAEELTAEAFGAEHAFFMVGGTTQAVQNMVLSVCKAGDEIIVPRNVHKSV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCHHHHHH
INALILCGAIPVYLNTEINAKLGIVLGVTVQQVEKTIQEHPNAVAVLVNNPTYYGICSDI
HHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEECCCEEEEEHHHH
KGICDIAHSYGLKVLADEAHGTHLYFGDNLPMNSMKAGADLAAISMHKSGGSLTQSSILL
HHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEE
TNNGMNADYVQTIINITQTTSASYLLMTSLDISRRNLALRGRQSFAKVSEWAQYARDEIN
ECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCHHHHHHHHHHHHHHHHHHH
MVGGYYAYGKELINGGTVYDYDVTKLCVYTRDIGLDGIEVYDILRDEYDIQIEFGDIGNI
HCCCHHHHHHHHHCCCEEEECCHHEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCE
MAYISIGDRIQDIERLVGALAEISRLYSKEEKRFEVDRQMLLPRVLASPQEAFYADKIKV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
PIREAAGHISGEFVMAYPPGIPILAPGEEITDEIIDYIQYSVEKGCSMQGMEDSTLQTLN
CHHHHCCCCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VLRM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]