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The map label for this gene is map [H]

Identifier: 238917319

GI number: 238917319

Start: 1438949

End: 1439824

Strand: Reverse

Name: map [H]

Synonym: EUBELI_01394

Alternate gene names: 238917319

Gene position: 1439824-1438949 (Counterclockwise)

Preceding gene: 238917320

Following gene: 238917317

Centisome position: 67.15

GC content: 40.64

Gene sequence:

>876_bases
ATGATTAAGAAATTAGGAAGAAACGACCATTGCTGGTGTGGCAGTGGTAAGAAATACAAAGCGTGTCATGAAGCATTTGA
CGATAAGTTAAGATATCTCGAGGATATTGGACATATTGTGCCATCACACAAGTTAATCAAGACACCTGAACAGATTGAGA
AAATTAAAGAGAGTGCCAGGATAAATGTTGCGTGCCTTGATGCGGTTGCAGCAGAAATACATGAGGGCATGAACACTGCG
GAGATTGATAAGATTGTATATGATGTAACCACTGATATGGGAGGAATTCCAGCACCACTTAATTATGAAGGATATCCTTA
CAGTGTGTGTACATCTGTTAATGAGCAGGTATGCCACGGATTTCCATCTAAGGATGTTATCCTTAAGTCAGGTGATATTG
TAAATGTTGACTGTTCTACAATTCTTCACGGATATTTTTCAGATTCATCAAGAATGTTCTGTATAGGTGATGTTAAGCCT
GAGGTAAAGAAGCTTGTTGATGTTACTAAGGAATGTGTTGAATTAGGACTTGAGCAGGTTAAGCCTTGGGGCTTCTTAGG
CGATATGGGACAGGCAGTACATGACCATGCATATGCTAATGGATATACTGTTGTAAGAGAAATCGGCGGCCATGGAGTCG
GACTTGAATTTCATGAAGACCCATGGGTTGGGTACAACACCAGAAAAGGAACAGATATGGTTATGGCTCCGGGAATGATG
TTTACAATAGAGCCTATGGTTAATATGGGTAAGGTAAATGTTGTTACAGATGAAAAGAACGGCTGGGAAGTATCTACAGC
TGATGGACTTCCTTCAGCACAGTGGGAAATTCAGGTTCTTGTAACAGAGGACGGACACGAAGTAATAAGTTGGTAA

Upstream 100 bases:

>100_bases
TGTTAATAATGATTAATCATTTGAAACAGATATTGAAAAAATATTAAGAAAGCCTTATAGTTGTGTATGATTATAATATA
TGTAACAGGAAGGCGGAACA

Downstream 100 bases:

>100_bases
GAAATAAAATAAGTTCCTGCCAATCAGGCACGCTTTCGCTGCTCTCGCCTCGCAGCGGTACTAAATTCGCGTTACACGCT
CATTAAGAACCGGCGGGCTC

Product: methionyl aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIKKLGRNDHCWCGSGKKYKACHEAFDDKLRYLEDIGHIVPSHKLIKTPEQIEKIKESARINVACLDAVAAEIHEGMNTA
EIDKIVYDVTTDMGGIPAPLNYEGYPYSVCTSVNEQVCHGFPSKDVILKSGDIVNVDCSTILHGYFSDSSRMFCIGDVKP
EVKKLVDVTKECVELGLEQVKPWGFLGDMGQAVHDHAYANGYTVVREIGGHGVGLEFHEDPWVGYNTRKGTDMVMAPGMM
FTIEPMVNMGKVNVVTDEKNGWEVSTADGLPSAQWEIQVLVTEDGHEVISW

Sequences:

>Translated_291_residues
MIKKLGRNDHCWCGSGKKYKACHEAFDDKLRYLEDIGHIVPSHKLIKTPEQIEKIKESARINVACLDAVAAEIHEGMNTA
EIDKIVYDVTTDMGGIPAPLNYEGYPYSVCTSVNEQVCHGFPSKDVILKSGDIVNVDCSTILHGYFSDSSRMFCIGDVKP
EVKKLVDVTKECVELGLEQVKPWGFLGDMGQAVHDHAYANGYTVVREIGGHGVGLEFHEDPWVGYNTRKGTDMVMAPGMM
FTIEPMVNMGKVNVVTDEKNGWEVSTADGLPSAQWEIQVLVTEDGHEVISW
>Mature_291_residues
MIKKLGRNDHCWCGSGKKYKACHEAFDDKLRYLEDIGHIVPSHKLIKTPEQIEKIKESARINVACLDAVAAEIHEGMNTA
EIDKIVYDVTTDMGGIPAPLNYEGYPYSVCTSVNEQVCHGFPSKDVILKSGDIVNVDCSTILHGYFSDSSRMFCIGDVKP
EVKKLVDVTKECVELGLEQVKPWGFLGDMGQAVHDHAYANGYTVVREIGGHGVGLEFHEDPWVGYNTRKGTDMVMAPGMM
FTIEPMVNMGKVNVVTDEKNGWEVSTADGLPSAQWEIQVLVTEDGHEVISW

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=39.3574297188755, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI40385867, Length=245, Percent_Identity=32.2448979591837, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=42.570281124498, Blast_Score=201, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI71996291, Length=254, Percent_Identity=37.7952755905512, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323273, Length=242, Percent_Identity=40.0826446280992, Blast_Score=183, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21355531, Length=241, Percent_Identity=37.7593360995851, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=32.7935222672065, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467
- InterPro:   IPR004027 [H]

Pfam domain/function: PF00557 Peptidase_M24; PF02810 SEC-C [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 32238; Mature: 32238

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLGRNDHCWCGSGKKYKACHEAFDDKLRYLEDIGHIVPSHKLIKTPEQIEKIKESAR
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHC
INVACLDAVAAEIHEGMNTAEIDKIVYDVTTDMGGIPAPLNYEGYPYSVCTSVNEQVCHG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHCC
FPSKDVILKSGDIVNVDCSTILHGYFSDSSRMFCIGDVKPEVKKLVDVTKECVELGLEQV
CCCCCEEEECCCEEEEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHC
KPWGFLGDMGQAVHDHAYANGYTVVREIGGHGVGLEFHEDPWVGYNTRKGTDMVMAPGMM
CCCCCHHHHHHHHHHHHHCCCCCEEEHHCCCCCCEEECCCCCCCCCCCCCCCEEECCCEE
FTIEPMVNMGKVNVVTDEKNGWEVSTADGLPSAQWEIQVLVTEDGHEVISW
EEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MIKKLGRNDHCWCGSGKKYKACHEAFDDKLRYLEDIGHIVPSHKLIKTPEQIEKIKESAR
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHC
INVACLDAVAAEIHEGMNTAEIDKIVYDVTTDMGGIPAPLNYEGYPYSVCTSVNEQVCHG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHCC
FPSKDVILKSGDIVNVDCSTILHGYFSDSSRMFCIGDVKPEVKKLVDVTKECVELGLEQV
CCCCCEEEECCCEEEEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHC
KPWGFLGDMGQAVHDHAYANGYTVVREIGGHGVGLEFHEDPWVGYNTRKGTDMVMAPGMM
CCCCCHHHHHHHHHHHHHCCCCCEEEHHCCCCCCEEECCCCCCCCCCCCCCCEEECCCEE
FTIEPMVNMGKVNVVTDEKNGWEVSTADGLPSAQWEIQVLVTEDGHEVISW
EEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]