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The map label for this gene is trpS [H]

Identifier: 238917261

GI number: 238917261

Start: 1368246

End: 1369337

Strand: Reverse

Name: trpS [H]

Synonym: EUBELI_01335

Alternate gene names: 238917261

Gene position: 1369337-1368246 (Counterclockwise)

Preceding gene: 238917262

Following gene: 238917260

Centisome position: 63.86

GC content: 37.45

Gene sequence:

>1092_bases
ATGTCTAAGATTATATTAACAGGTGACAGACCAACCGGAAGACTTCACTTAGGTCATTATGTTGGATCTTTAAAGCGAAG
AGTTGAATTACAGAATTCAGGTGAATACGAGAAGATTTTTATTATGATTGCGGATGCACAGGCATTAACAGATAATGCTG
ATAATCCGGAGAAAGTAAGACAGAACATAATCGAGGTTGCACTCGATTATCTTTCAGTTGGTATTGATCCAGCTAAGTCT
AATATATTTATCCAGTCACAGATTTCACAGCTTACAGAGCTTACATTTTATTATATGAACCTCGTTACAGTTTCAAGACT
TCAGAGAAACCCTACAGTTAAATCTGAGATTCAGATGCGTAATTTTGAGGCTAGTATTCCGGTAGGATTTTTCTGTTATC
CTATAAGCCAGGCTGCGGATATTACTGCATTTAAGGCTACTACAGTTCCTGTAGGAGAAGATCAGGAACCTATGATTGAG
CAGTGCCGTGAGATTGTAAGAAAGTTTAACTCTGTATACGGAGAGGCTCTTGTTGAACCTGAGATTCTTCTTCCAGATAA
TAAGGCATGTTTAAGACTTCCTGGTACTGATGGTAAGGCTAAGATGAGCAAGTCATTAGGAAATTGTATTTACTTATCTG
ACACTCCAGAGGAAGTTAAGAAAAAGGTTATGAGTATGTACACAGACCCTAACCATATTCAGGTATCTGATCCTGGACAG
GTTGAGGGTAACACAGTATTTACTTATCTTGATGCTTTCAGCAGTGATGAGGATTTTGCTGAATTCCTTCCTGATTATAA
GAATCTTGATGAATTAAAGGATCATTACAGAAGAGGTGGTCTTGGAGACGTTAAGGTTAAGAAGTTCCTTCTTAATGTTA
TCAACAAGGAGCTTGAACCAATCAGAGCAAGAAGACATGAATATGAAAAGGATATTCCAGAAGTATATAATATCCTTAAG
AGAGGTACAGAAGCGGCTTATGCTGTTGCACAGGACACTCTTGATGATGTCAAGGCTGCTATGAAGATTGATTATTTTAA
TGATGCAGAACTTATTAAGGTTCAGTCAGAAAAATACAGCAGAACAGAGTAA

Upstream 100 bases:

>100_bases
GAATTGCAGTTATTCTGCCAATTTATATTAAACTATTTTGCCATTTGCGTAAAAGTATGATATAATTTTTACAATTTTGG
GATGAGGAAAGGTGGCGCTT

Downstream 100 bases:

>100_bases
TTATTTTAATTAAATATACACACGGAGGCTTTTCTATTATGAGACATTTACTTAGTCCGCTTGATTTAAGCGTTGATGAA
CTGGCAAGATTATTAGATCT

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSKIILTGDRPTGRLHLGHYVGSLKRRVELQNSGEYEKIFIMIADAQALTDNADNPEKVRQNIIEVALDYLSVGIDPAKS
NIFIQSQISQLTELTFYYMNLVTVSRLQRNPTVKSEIQMRNFEASIPVGFFCYPISQAADITAFKATTVPVGEDQEPMIE
QCREIVRKFNSVYGEALVEPEILLPDNKACLRLPGTDGKAKMSKSLGNCIYLSDTPEEVKKKVMSMYTDPNHIQVSDPGQ
VEGNTVFTYLDAFSSDEDFAEFLPDYKNLDELKDHYRRGGLGDVKVKKFLLNVINKELEPIRARRHEYEKDIPEVYNILK
RGTEAAYAVAQDTLDDVKAAMKIDYFNDAELIKVQSEKYSRTE

Sequences:

>Translated_363_residues
MSKIILTGDRPTGRLHLGHYVGSLKRRVELQNSGEYEKIFIMIADAQALTDNADNPEKVRQNIIEVALDYLSVGIDPAKS
NIFIQSQISQLTELTFYYMNLVTVSRLQRNPTVKSEIQMRNFEASIPVGFFCYPISQAADITAFKATTVPVGEDQEPMIE
QCREIVRKFNSVYGEALVEPEILLPDNKACLRLPGTDGKAKMSKSLGNCIYLSDTPEEVKKKVMSMYTDPNHIQVSDPGQ
VEGNTVFTYLDAFSSDEDFAEFLPDYKNLDELKDHYRRGGLGDVKVKKFLLNVINKELEPIRARRHEYEKDIPEVYNILK
RGTEAAYAVAQDTLDDVKAAMKIDYFNDAELIKVQSEKYSRTE
>Mature_362_residues
SKIILTGDRPTGRLHLGHYVGSLKRRVELQNSGEYEKIFIMIADAQALTDNADNPEKVRQNIIEVALDYLSVGIDPAKSN
IFIQSQISQLTELTFYYMNLVTVSRLQRNPTVKSEIQMRNFEASIPVGFFCYPISQAADITAFKATTVPVGEDQEPMIEQ
CREIVRKFNSVYGEALVEPEILLPDNKACLRLPGTDGKAKMSKSLGNCIYLSDTPEEVKKKVMSMYTDPNHIQVSDPGQV
EGNTVFTYLDAFSSDEDFAEFLPDYKNLDELKDHYRRGGLGDVKVKKFLLNVINKELEPIRARRHEYEKDIPEVYNILKR
GTEAAYAVAQDTLDDVKAAMKIDYFNDAELIKVQSEKYSRTE

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=337, Percent_Identity=30.5637982195846, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI41352700, Length=182, Percent_Identity=37.9120879120879, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789786, Length=341, Percent_Identity=29.3255131964809, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71982800, Length=345, Percent_Identity=29.5652173913043, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982793, Length=349, Percent_Identity=29.7994269340974, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320474, Length=361, Percent_Identity=29.9168975069252, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24666151, Length=337, Percent_Identity=30.5637982195846, Blast_Score=160, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 41192; Mature: 41061

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIILTGDRPTGRLHLGHYVGSLKRRVELQNSGEYEKIFIMIADAQALTDNADNPEKVR
CCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCCCCHHHHH
QNIIEVALDYLSVGIDPAKSNIFIQSQISQLTELTFYYMNLVTVSRLQRNPTVKSEIQMR
HHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NFEASIPVGFFCYPISQAADITAFKATTVPVGEDQEPMIEQCREIVRKFNSVYGEALVEP
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EILLPDNKACLRLPGTDGKAKMSKSLGNCIYLSDTPEEVKKKVMSMYTDPNHIQVSDPGQ
CEECCCCCCEEEECCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCC
VEGNTVFTYLDAFSSDEDFAEFLPDYKNLDELKDHYRRGGLGDVKVKKFLLNVINKELEP
CCCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRARRHEYEKDIPEVYNILKRGTEAAYAVAQDTLDDVKAAMKIDYFNDAELIKVQSEKYS
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCC
RTE
CCC
>Mature Secondary Structure 
SKIILTGDRPTGRLHLGHYVGSLKRRVELQNSGEYEKIFIMIADAQALTDNADNPEKVR
CCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCCCCHHHHH
QNIIEVALDYLSVGIDPAKSNIFIQSQISQLTELTFYYMNLVTVSRLQRNPTVKSEIQMR
HHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NFEASIPVGFFCYPISQAADITAFKATTVPVGEDQEPMIEQCREIVRKFNSVYGEALVEP
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EILLPDNKACLRLPGTDGKAKMSKSLGNCIYLSDTPEEVKKKVMSMYTDPNHIQVSDPGQ
CEECCCCCCEEEECCCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCC
VEGNTVFTYLDAFSSDEDFAEFLPDYKNLDELKDHYRRGGLGDVKVKKFLLNVINKELEP
CCCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRARRHEYEKDIPEVYNILKRGTEAAYAVAQDTLDDVKAAMKIDYFNDAELIKVQSEKYS
HHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCC
RTE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA