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The map label for this gene is aroE [H]

Identifier: 238917253

GI number: 238917253

Start: 1362569

End: 1363441

Strand: Reverse

Name: aroE [H]

Synonym: EUBELI_01327

Alternate gene names: 238917253

Gene position: 1363441-1362569 (Counterclockwise)

Preceding gene: 238917254

Following gene: 238917252

Centisome position: 63.59

GC content: 38.49

Gene sequence:

>873_bases
ATGGACATCAAAGGAACAACAAGAGTATGCGGACTTATTGGTAATCCGGTAGGACATTCTGTGTCACCGGCAATTCATAA
TAATCTTGCACGGCTGACAGGAAAAGATATGGTTTATACTACATTTAAAGTGGAAAAAGGAGATGTGGAAGCTGCTGTAA
GGGGCGCTTACAGTCTTAATATACTGGGACTTAATGTCACTGTTCCACACAAGTCAGAGGTTATTGATTCTCTTGTAGAC
ATAGATCCGCTTGCAAAGGCTATAGGTGCTGTTAATACTCTTGTAAGAGCTGATGGTGGATTTAAAGGATATAACACTGA
TATTCTTGGCCTTGCAAGGGAACTTGAAGATGAAGGAATTGAACTGGCTGATTCTAAGGTTATTATTCTGGGAGCAGGAG
GCGCAGCAAGAGCTATTACTTTTCTTTGTTCAAGTAAGGGAGCAAAGAAAATTTATCTGTTGAACAGATCTGTAGATAAG
GCACAGGATATAGCGCATGCTGTGAATACACATTTTAACAATGAAAAAGTAATTCCTATGAATATTGCTGATTATGCGGA
TATTCCAGGAGATGATTATATTGTTATCCAGACAACAAGCGTTGGACTTCACCCGAATGATACTGCAGTTGTTATTGATG
ATGAATCATTTTATAAGAAGGCGGCAGTTGGTGTTGATATTATATATAATCCGGCTGAGACTATGTTTATGAAGCTTATC
AAGGCACAGGGGAAAAAGGCTTATAATGGACTTAAGATGCTTCTGTATCAGGGAGTAAGTGCTTATGAACTCTGGAATGA
CTGTAAGATTTCTAAAAAAGAAGCGGATGAAGTATATAAGTGTCTTGAGAAGGAGCTTGGGATTAATGAATAG

Upstream 100 bases:

>100_bases
GCATGAAGAAATTCAGATAATTCTTAAGAGAAGACTGGAATGGATTGTATTATTTTTCTATAAAAGAAGAAAGCATTAAT
TGCTTAAAGGAGCTTAGATT

Downstream 100 bases:

>100_bases
TAAGAATAATATTATCCTTATTGGTTTTATGGGAAGCGGTAAGACTACATTTGGCAGGTGGATATCGATGTCCCATTCAA
TGAAGTTCCTTGATACTGAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDIKGTTRVCGLIGNPVGHSVSPAIHNNLARLTGKDMVYTTFKVEKGDVEAAVRGAYSLNILGLNVTVPHKSEVIDSLVD
IDPLAKAIGAVNTLVRADGGFKGYNTDILGLARELEDEGIELADSKVIILGAGGAARAITFLCSSKGAKKIYLLNRSVDK
AQDIAHAVNTHFNNEKVIPMNIADYADIPGDDYIVIQTTSVGLHPNDTAVVIDDESFYKKAAVGVDIIYNPAETMFMKLI
KAQGKKAYNGLKMLLYQGVSAYELWNDCKISKKEADEVYKCLEKELGINE

Sequences:

>Translated_290_residues
MDIKGTTRVCGLIGNPVGHSVSPAIHNNLARLTGKDMVYTTFKVEKGDVEAAVRGAYSLNILGLNVTVPHKSEVIDSLVD
IDPLAKAIGAVNTLVRADGGFKGYNTDILGLARELEDEGIELADSKVIILGAGGAARAITFLCSSKGAKKIYLLNRSVDK
AQDIAHAVNTHFNNEKVIPMNIADYADIPGDDYIVIQTTSVGLHPNDTAVVIDDESFYKKAAVGVDIIYNPAETMFMKLI
KAQGKKAYNGLKMLLYQGVSAYELWNDCKISKKEADEVYKCLEKELGINE
>Mature_290_residues
MDIKGTTRVCGLIGNPVGHSVSPAIHNNLARLTGKDMVYTTFKVEKGDVEAAVRGAYSLNILGLNVTVPHKSEVIDSLVD
IDPLAKAIGAVNTLVRADGGFKGYNTDILGLARELEDEGIELADSKVIILGAGGAARAITFLCSSKGAKKIYLLNRSVDK
AQDIAHAVNTHFNNEKVIPMNIADYADIPGDDYIVIQTTSVGLHPNDTAVVIDDESFYKKAAVGVDIIYNPAETMFMKLI
KAQGKKAYNGLKMLLYQGVSAYELWNDCKISKKEADEVYKCLEKELGINE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=273, Percent_Identity=31.1355311355311, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=28.4172661870504, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=275, Percent_Identity=28.7272727272727, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31364; Mature: 31364

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKGTTRVCGLIGNPVGHSVSPAIHNNLARLTGKDMVYTTFKVEKGDVEAAVRGAYSLN
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHCCEEEE
ILGLNVTVPHKSEVIDSLVDIDPLAKAIGAVNTLVRADGGFKGYNTDILGLARELEDEGI
EEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
ELADSKVIILGAGGAARAITFLCSSKGAKKIYLLNRSVDKAQDIAHAVNTHFNNEKVIPM
EEECCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEE
NIADYADIPGDDYIVIQTTSVGLHPNDTAVVIDDESFYKKAAVGVDIIYNPAETMFMKLI
ECHHCCCCCCCCEEEEEEEEECCCCCCCEEEEECHHHHHHHHCCEEEEECCHHHHHHHHH
KAQGKKAYNGLKMLLYQGVSAYELWNDCKISKKEADEVYKCLEKELGINE
HHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDIKGTTRVCGLIGNPVGHSVSPAIHNNLARLTGKDMVYTTFKVEKGDVEAAVRGAYSLN
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHCCEEEE
ILGLNVTVPHKSEVIDSLVDIDPLAKAIGAVNTLVRADGGFKGYNTDILGLARELEDEGI
EEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
ELADSKVIILGAGGAARAITFLCSSKGAKKIYLLNRSVDKAQDIAHAVNTHFNNEKVIPM
EEECCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEE
NIADYADIPGDDYIVIQTTSVGLHPNDTAVVIDDESFYKKAAVGVDIIYNPAETMFMKLI
ECHHCCCCCCCCEEEEEEEEECCCCCCCEEEEECHHHHHHHHCCEEEEECCHHHHHHHHH
KAQGKKAYNGLKMLLYQGVSAYELWNDCKISKKEADEVYKCLEKELGINE
HHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA