Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 238917252

GI number: 238917252

Start: 1362043

End: 1362576

Strand: Reverse

Name: aroK [H]

Synonym: EUBELI_01326

Alternate gene names: 238917252

Gene position: 1362576-1362043 (Counterclockwise)

Preceding gene: 238917253

Following gene: 238917251

Centisome position: 63.55

GC content: 37.83

Gene sequence:

>534_bases
ATGAATAGTAAGAATAATATTATCCTTATTGGTTTTATGGGAAGCGGTAAGACTACATTTGGCAGGTGGATATCGATGTC
CCATTCAATGAAGTTCCTTGATACTGATGAGTACATAGAAAAAAAATACAATAAGCTTATTAAGGATATATTTAGAGAGT
CAGGAGAAGAAGCCTTCAGGGATATGGAGACACAGGCAGTCAGAGAACTTGCTGATTCATGTGATAACTGTGTTATATCT
GTTGGAGGAGGGCTGCCGGTAAGAGATATTAACCGCAGGCTTCTTAAAGAGCTTGGAGTAGTTGTATATCTTGAAGCTGA
AGTTGATGAACTTGTAAAAAGACTGTCTAAGGATACAAGCAGACCACTTCTTGCGGGAGGTAACTTAAGAGAAAAGATTG
AAAGTCTTATGACTGCAAGGGAGGAGCTTTATAAGGATGCCGCTGATGTTATAGTTAAGACTGATGGAAGAAGATTTGAA
GACATGTATGCTGATATAGTTTCAGCTATTAATATAGGCATAATGGAGGATTGA

Upstream 100 bases:

>100_bases
TATCAGGGAGTAAGTGCTTATGAACTCTGGAATGACTGTAAGATTTCTAAAAAAGAAGCGGATGAAGTATATAAGTGTCT
TGAGAAGGAGCTTGGGATTA

Downstream 100 bases:

>100_bases
TATGAAGATACTTGTAATGAATGGACCTAACATTAATTTTCTTGGAATAAGAGAGAAAGGTATATATGGAGAGCAGAATT
ATGAAGCTCTTGTTTCAATG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNSKNNIILIGFMGSGKTTFGRWISMSHSMKFLDTDEYIEKKYNKLIKDIFRESGEEAFRDMETQAVRELADSCDNCVIS
VGGGLPVRDINRRLLKELGVVVYLEAEVDELVKRLSKDTSRPLLAGGNLREKIESLMTAREELYKDAADVIVKTDGRRFE
DMYADIVSAINIGIMED

Sequences:

>Translated_177_residues
MNSKNNIILIGFMGSGKTTFGRWISMSHSMKFLDTDEYIEKKYNKLIKDIFRESGEEAFRDMETQAVRELADSCDNCVIS
VGGGLPVRDINRRLLKELGVVVYLEAEVDELVKRLSKDTSRPLLAGGNLREKIESLMTAREELYKDAADVIVKTDGRRFE
DMYADIVSAINIGIMED
>Mature_177_residues
MNSKNNIILIGFMGSGKTTFGRWISMSHSMKFLDTDEYIEKKYNKLIKDIFRESGEEAFRDMETQAVRELADSCDNCVIS
VGGGLPVRDINRRLLKELGVVVYLEAEVDELVKRLSKDTSRPLLAGGNLREKIESLMTAREELYKDAADVIVKTDGRRFE
DMYADIVSAINIGIMED

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=168, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87082255, Length=177, Percent_Identity=37.2881355932203, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786587, Length=149, Percent_Identity=34.2281879194631, Blast_Score=93, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=155, Percent_Identity=31.6129032258064, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20052; Mature: 20052

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKNNIILIGFMGSGKTTFGRWISMSHSMKFLDTDEYIEKKYNKLIKDIFRESGEEAFR
CCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHH
DMETQAVRELADSCDNCVISVGGGLPVRDINRRLLKELGVVVYLEAEVDELVKRLSKDTS
HHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCC
RPLLAGGNLREKIESLMTAREELYKDAADVIVKTDGRRFEDMYADIVSAINIGIMED
CCEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNSKNNIILIGFMGSGKTTFGRWISMSHSMKFLDTDEYIEKKYNKLIKDIFRESGEEAFR
CCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCHHHHHH
DMETQAVRELADSCDNCVISVGGGLPVRDINRRLLKELGVVVYLEAEVDELVKRLSKDTS
HHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCC
RPLLAGGNLREKIESLMTAREELYKDAADVIVKTDGRRFEDMYADIVSAINIGIMED
CCEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA