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The map label for this gene is yicO [C]

Identifier: 238917211

GI number: 238917211

Start: 1321827

End: 1323194

Strand: Reverse

Name: yicO [C]

Synonym: EUBELI_01284

Alternate gene names: 238917211

Gene position: 1323194-1321827 (Counterclockwise)

Preceding gene: 238917212

Following gene: 238917210

Centisome position: 61.71

GC content: 37.79

Gene sequence:

>1368_bases
ATGGAGGTTGAAATGGACAAATTGTTCAAACTTAAGGAAAACAACACCAGTGTAAGAACTGAGGTTGTAGCTGGAATTAC
AACATTTATGACAATGGCTTATATTCTGGCTGTTAATCCATCTATCCTGTCAGCATCAGGAATGGATTCTAATGCAATTC
TTATGGCGACTGCAATAGCATCTGCTATAGGTTGTTTTGCAATGGCTTTCCTTGCTAATTATCCTTTTGCACTTGCTCCA
GGACTTGGACTTAACGCTTATTTCGCATATACAGTATGCGGAAGCATGGGATATAGCTGGAAAGTAGCACTTTTTGCTGT
ATTTGTTGAAGGACTTGTATTTATTGTGCTTTCACTTACTAATGTTCGTGAAGCTATATTTAACGCAATTCCTACAACAT
TAAAGAAGGGCGTATCAGTAGGTATCGGTCTTTTTGTGGCATTTATCGGACTTCAGGGTGCTAACCTAGTTGTTGCAAGT
GAGTCAACAAAGGTTACTGTTGTTAATTTCAGAACTAATTTTAACACAGTAGGAATAGGTGCTTTACTTGCAGTTATCGG
TACATTTATCATTGCTATTCTTTATGTAAAGCATGTTAAGGGTTCTATCCTTATCGGTATCGTTGCAACATGGGTGCTTG
GTATTATCTGCCAGCTTACAGGACTTTATAAGGTTGATGCAGCAGCAGGATTCTATTCACTTATTCCTTCATGGAGAAGC
TTTGATATCACAGCTATCAGCCTGACATTTGGACAGTGCTTTAACCTTAAGGGTCTTAATATTAATATATTAGATTTTAT
TGTTATTATGTGCTCATTCCTTTTTGTTGACATGTTTGATACACTTGGAACACTTATCGGTGTTGCCAATAAGGCTAAAA
TGCTTGATGAGAACGGAAGACTTCCTAGAATTAAGCAGGCTCTTTTAGCTGATGCTATCGCAACAAGTGCAGGAGCCATC
CTTGGTACTTCTACAACAACAACATTTGTTGAGAGCTCATCAGGTGTTGCAGAAGGCGGAAGAACAGGACTTTCTTCAGT
TGTAACAGGTTTCTTATTCCTTATTGCAATTATATTTGCACCTGTATTTACTACAATTCCTGGATTTGCAACAGCTCCGG
CACTTATTTTTGTAGGATTCCTTATGGTTAGTGCGGTTGTTGAAATTGATTTTAATGATTTAACAGAGAGTATTCCGGCT
TACCTCTGCCTTATCTGTATGCCGCTTATGTACAGCATTTCAGAAGGTATTGCAGTTGGTGTTATTTCGTATGTTATTGT
TAATCTTGTTGCTGGAAAGGCTAAGAAGATTACTCCACTTATGTACGTGCTTGCATTGCTGTTCATATTGAAGTATATTT
TCCTTTAA

Upstream 100 bases:

>100_bases
AGATTTTATTAGAAAAGATATATGTCTAATAAAAAAAGTTGTCGTAAAATTGAGAAGAATATGTTAATATTATTAAGTGT
TTTTTAATATTTATAAAATT

Downstream 100 bases:

>100_bases
TTTTTAGTGCAAATTAAACTTAATAATGATACAATTTTGGAGTCACTTATATAAGGTGGCTCCTTTTTTAAGTTGAATGT
TAAAAGATAAGGGGACTGGG

Product: MFS transporter xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MEVEMDKLFKLKENNTSVRTEVVAGITTFMTMAYILAVNPSILSASGMDSNAILMATAIASAIGCFAMAFLANYPFALAP
GLGLNAYFAYTVCGSMGYSWKVALFAVFVEGLVFIVLSLTNVREAIFNAIPTTLKKGVSVGIGLFVAFIGLQGANLVVAS
ESTKVTVVNFRTNFNTVGIGALLAVIGTFIIAILYVKHVKGSILIGIVATWVLGIICQLTGLYKVDAAAGFYSLIPSWRS
FDITAISLTFGQCFNLKGLNINILDFIVIMCSFLFVDMFDTLGTLIGVANKAKMLDENGRLPRIKQALLADAIATSAGAI
LGTSTTTTFVESSSGVAEGGRTGLSSVVTGFLFLIAIIFAPVFTTIPGFATAPALIFVGFLMVSAVVEIDFNDLTESIPA
YLCLICMPLMYSISEGIAVGVISYVIVNLVAGKAKKITPLMYVLALLFILKYIFL

Sequences:

>Translated_455_residues
MEVEMDKLFKLKENNTSVRTEVVAGITTFMTMAYILAVNPSILSASGMDSNAILMATAIASAIGCFAMAFLANYPFALAP
GLGLNAYFAYTVCGSMGYSWKVALFAVFVEGLVFIVLSLTNVREAIFNAIPTTLKKGVSVGIGLFVAFIGLQGANLVVAS
ESTKVTVVNFRTNFNTVGIGALLAVIGTFIIAILYVKHVKGSILIGIVATWVLGIICQLTGLYKVDAAAGFYSLIPSWRS
FDITAISLTFGQCFNLKGLNINILDFIVIMCSFLFVDMFDTLGTLIGVANKAKMLDENGRLPRIKQALLADAIATSAGAI
LGTSTTTTFVESSSGVAEGGRTGLSSVVTGFLFLIAIIFAPVFTTIPGFATAPALIFVGFLMVSAVVEIDFNDLTESIPA
YLCLICMPLMYSISEGIAVGVISYVIVNLVAGKAKKITPLMYVLALLFILKYIFL
>Mature_455_residues
MEVEMDKLFKLKENNTSVRTEVVAGITTFMTMAYILAVNPSILSASGMDSNAILMATAIASAIGCFAMAFLANYPFALAP
GLGLNAYFAYTVCGSMGYSWKVALFAVFVEGLVFIVLSLTNVREAIFNAIPTTLKKGVSVGIGLFVAFIGLQGANLVVAS
ESTKVTVVNFRTNFNTVGIGALLAVIGTFIIAILYVKHVKGSILIGIVATWVLGIICQLTGLYKVDAAAGFYSLIPSWRS
FDITAISLTFGQCFNLKGLNINILDFIVIMCSFLFVDMFDTLGTLIGVANKAKMLDENGRLPRIKQALLADAIATSAGAI
LGTSTTTTFVESSSGVAEGGRTGLSSVVTGFLFLIAIIFAPVFTTIPGFATAPALIFVGFLMVSAVVEIDFNDLTESIPA
YLCLICMPLMYSISEGIAVGVISYVIVNLVAGKAKKITPLMYVLALLFILKYIFL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=452, Percent_Identity=40.2654867256637, Blast_Score=335, Evalue=5e-93,
Organism=Escherichia coli, GI1790150, Length=455, Percent_Identity=41.0989010989011, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1790499, Length=455, Percent_Identity=30.5494505494506, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI48994909, Length=438, Percent_Identity=31.2785388127854, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48340; Mature: 48340

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVEMDKLFKLKENNTSVRTEVVAGITTFMTMAYILAVNPSILSASGMDSNAILMATAIA
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHH
SAIGCFAMAFLANYPFALAPGLGLNAYFAYTVCGSMGYSWKVALFAVFVEGLVFIVLSLT
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NVREAIFNAIPTTLKKGVSVGIGLFVAFIGLQGANLVVASESTKVTVVNFRTNFNTVGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCHHHHH
ALLAVIGTFIIAILYVKHVKGSILIGIVATWVLGIICQLTGLYKVDAAAGFYSLIPSWRS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCC
FDITAISLTFGQCFNLKGLNINILDFIVIMCSFLFVDMFDTLGTLIGVANKAKMLDENGR
CCEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPRIKQALLADAIATSAGAILGTSTTTTFVESSSGVAEGGRTGLSSVVTGFLFLIAIIFA
CHHHHHHHHHHHHHHCCCCEEECCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PVFTTIPGFATAPALIFVGFLMVSAVVEIDFNDLTESIPAYLCLICMPLMYSISEGIAVG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VISYVIVNLVAGKAKKITPLMYVLALLFILKYIFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEVEMDKLFKLKENNTSVRTEVVAGITTFMTMAYILAVNPSILSASGMDSNAILMATAIA
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHH
SAIGCFAMAFLANYPFALAPGLGLNAYFAYTVCGSMGYSWKVALFAVFVEGLVFIVLSLT
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NVREAIFNAIPTTLKKGVSVGIGLFVAFIGLQGANLVVASESTKVTVVNFRTNFNTVGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCHHHHH
ALLAVIGTFIIAILYVKHVKGSILIGIVATWVLGIICQLTGLYKVDAAAGFYSLIPSWRS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCC
FDITAISLTFGQCFNLKGLNINILDFIVIMCSFLFVDMFDTLGTLIGVANKAKMLDENGR
CCEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPRIKQALLADAIATSAGAILGTSTTTTFVESSSGVAEGGRTGLSSVVTGFLFLIAIIFA
CHHHHHHHHHHHHHHCCCCEEECCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PVFTTIPGFATAPALIFVGFLMVSAVVEIDFNDLTESIPAYLCLICMPLMYSISEGIAVG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VISYVIVNLVAGKAKKITPLMYVLALLFILKYIFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]