Click here to switch to the map view.

The map label for this gene is ttuD [H]

Identifier: 238917188

GI number: 238917188

Start: 1293603

End: 1294880

Strand: Reverse

Name: ttuD [H]

Synonym: EUBELI_01261

Alternate gene names: 238917188

Gene position: 1294880-1293603 (Counterclockwise)

Preceding gene: 238917189

Following gene: 238917187

Centisome position: 60.39

GC content: 38.89

Gene sequence:

>1278_bases
ATGTTGTTGACAGGTTATTATAATGTCAGGAAGGAGAATCTTATGAATAAAGAATTAAGAGCGGTTGCAGACAATATAAT
TGATGCGGCAATTAAAGCAGTTCTTCCGGATGAAGCAGTTAAGAAAACACTTAATGACAGGAAATTTGATGGAAAAGTTA
TTCTTGTAGCAGTAGGAAAAGCCGCATGGCAGATGGCAAAGGCGGCAAGTGACTGTCTGGGAGACAGAATAAATGAAGGA
ATTGTAATAACGAAGTATGGACATGTAAAAGAGCCGATTGAAAGAATAGAATGTTTTGAGGCAGGCCACCCTGTTCCAGA
TGAGAATTCATTTAAAGCAACACAGGCAGCTATTGAGATGGTAAGCGGACTCAATAAGAATGATACAGTGCTTTTTCTTC
TTTCAGGTGGAGGAAGTGCTTTATTTGAGAAGCCGAAGATTACAGGAGAAGAATTGCAGGATATAACTAATCAGTTACTT
GCATGCGGTGCAGATATTGTTGAGATTAATACGATAAGAAAACGCTTATCAGAAGTAAAGGGCGGACGGTTTGCAAAATT
ATGTGAACCGGCGCATGTATTATCAATAGTATTATCAGATATACTTGGTGACCCACTGGATATGATTGCTTCAGGTCCGG
CATGTGCAGATACAACAACATGTGAAGAAGCAAAACATATTGTAGAAAAATATAATCTGAATCTTAGTGAGATGGCTAAT
AAACTGATGGATATTGAAACTCCAAAGAAACTTGATAACGTAACAACATTTATTAATGGAAGTGTGCGTGAATTATGCAG
TGCAGTTTCAAGAGAGTGCTTACAGTATGGATATGAACCAGTAATGCTTACTGACCAGCTATGCTGTCAGGCAAAAGAAG
CCGGAAGTTTTCTTGCATCTATAGCAAAGACACATTGTAAGTCAGGAAAGAAGCTGGCATACATAGCAGGCGGAGAAACT
GTTGTTAATATTACCGGACATGGTAAAGGCGGAAGAAATCAGGAGATTGCATTATCAGCAGCAGAAGGTATTAAGGGAAT
GTCAAATGCAGCAGTATTCAGTATAGGCAGCGATGGAACAGACGGACCTACGGATGCGGCAGGTGGATATAGCGATGGTG
ATACAGCAGGAGTCTTAAAGAATAAAGGAATAGATATATTTGAAGTGCTTAAGAATAATGATGCTTATAATGCATTGAAA
CTAACAGAGGGGCTTATTATAACAGGTCCTACGGGAACAAATGTTAATGATGTTTCTGTGCTGCTTATATCAGATTGA

Upstream 100 bases:

>100_bases
TCAGGAAATAATGCAGTATCTGCATAATAATGGAGATGGAAGCAGCGACCACAGTGCAATTATACATTATTATGAAAAAC
TGGCAGACACAAAATTATAA

Downstream 100 bases:

>100_bases
TAAGGTACATAAAGCGATAAAAATATATAATTTAATTATTTATTATAGTGTAAAGCCAGTATTTTGCTGGCTTTATATTT
TTTTAATAAATTCATTAGCA

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLLTGYYNVRKENLMNKELRAVADNIIDAAIKAVLPDEAVKKTLNDRKFDGKVILVAVGKAAWQMAKAASDCLGDRINEG
IVITKYGHVKEPIERIECFEAGHPVPDENSFKATQAAIEMVSGLNKNDTVLFLLSGGGSALFEKPKITGEELQDITNQLL
ACGADIVEINTIRKRLSEVKGGRFAKLCEPAHVLSIVLSDILGDPLDMIASGPACADTTTCEEAKHIVEKYNLNLSEMAN
KLMDIETPKKLDNVTTFINGSVRELCSAVSRECLQYGYEPVMLTDQLCCQAKEAGSFLASIAKTHCKSGKKLAYIAGGET
VVNITGHGKGGRNQEIALSAAEGIKGMSNAAVFSIGSDGTDGPTDAAGGYSDGDTAGVLKNKGIDIFEVLKNNDAYNALK
LTEGLIITGPTGTNVNDVSVLLISD

Sequences:

>Translated_425_residues
MLLTGYYNVRKENLMNKELRAVADNIIDAAIKAVLPDEAVKKTLNDRKFDGKVILVAVGKAAWQMAKAASDCLGDRINEG
IVITKYGHVKEPIERIECFEAGHPVPDENSFKATQAAIEMVSGLNKNDTVLFLLSGGGSALFEKPKITGEELQDITNQLL
ACGADIVEINTIRKRLSEVKGGRFAKLCEPAHVLSIVLSDILGDPLDMIASGPACADTTTCEEAKHIVEKYNLNLSEMAN
KLMDIETPKKLDNVTTFINGSVRELCSAVSRECLQYGYEPVMLTDQLCCQAKEAGSFLASIAKTHCKSGKKLAYIAGGET
VVNITGHGKGGRNQEIALSAAEGIKGMSNAAVFSIGSDGTDGPTDAAGGYSDGDTAGVLKNKGIDIFEVLKNNDAYNALK
LTEGLIITGPTGTNVNDVSVLLISD
>Mature_425_residues
MLLTGYYNVRKENLMNKELRAVADNIIDAAIKAVLPDEAVKKTLNDRKFDGKVILVAVGKAAWQMAKAASDCLGDRINEG
IVITKYGHVKEPIERIECFEAGHPVPDENSFKATQAAIEMVSGLNKNDTVLFLLSGGGSALFEKPKITGEELQDITNQLL
ACGADIVEINTIRKRLSEVKGGRFAKLCEPAHVLSIVLSDILGDPLDMIASGPACADTTTCEEAKHIVEKYNLNLSEMAN
KLMDIETPKKLDNVTTFINGSVRELCSAVSRECLQYGYEPVMLTDQLCCQAKEAGSFLASIAKTHCKSGKKLAYIAGGET
VVNITGHGKGGRNQEIALSAAEGIKGMSNAAVFSIGSDGTDGPTDAAGGYSDGDTAGVLKNKGIDIFEVLKNNDAYNALK
LTEGLIITGPTGTNVNDVSVLLISD

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=483, Percent_Identity=31.055900621118, Blast_Score=208, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI193205461, Length=410, Percent_Identity=31.7073170731707, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI19920578, Length=429, Percent_Identity=30.5361305361305, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 45274; Mature: 45274

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTGYYNVRKENLMNKELRAVADNIIDAAIKAVLPDEAVKKTLNDRKFDGKVILVAVGK
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECH
AAWQMAKAASDCLGDRINEGIVITKYGHVKEPIERIECFEAGHPVPDENSFKATQAAIEM
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VSGLNKNDTVLFLLSGGGSALFEKPKITGEELQDITNQLLACGADIVEINTIRKRLSEVK
HHCCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GGRFAKLCEPAHVLSIVLSDILGDPLDMIASGPACADTTTCEEAKHIVEKYNLNLSEMAN
CCCHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
KLMDIETPKKLDNVTTFINGSVRELCSAVSRECLQYGYEPVMLTDQLCCQAKEAGSFLAS
HHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHH
IAKTHCKSGKKLAYIAGGETVVNITGHGKGGRNQEIALSAAEGIKGMSNAAVFSIGSDGT
HHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCC
DGPTDAAGGYSDGDTAGVLKNKGIDIFEVLKNNDAYNALKLTEGLIITGPTGTNVNDVSV
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCEEE
LLISD
EEEEC
>Mature Secondary Structure
MLLTGYYNVRKENLMNKELRAVADNIIDAAIKAVLPDEAVKKTLNDRKFDGKVILVAVGK
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEECH
AAWQMAKAASDCLGDRINEGIVITKYGHVKEPIERIECFEAGHPVPDENSFKATQAAIEM
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VSGLNKNDTVLFLLSGGGSALFEKPKITGEELQDITNQLLACGADIVEINTIRKRLSEVK
HHCCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GGRFAKLCEPAHVLSIVLSDILGDPLDMIASGPACADTTTCEEAKHIVEKYNLNLSEMAN
CCCHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
KLMDIETPKKLDNVTTFINGSVRELCSAVSRECLQYGYEPVMLTDQLCCQAKEAGSFLAS
HHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHH
IAKTHCKSGKKLAYIAGGETVVNITGHGKGGRNQEIALSAAEGIKGMSNAAVFSIGSDGT
HHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCC
DGPTDAAGGYSDGDTAGVLKNKGIDIFEVLKNNDAYNALKLTEGLIITGPTGTNVNDVSV
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCEEE
LLISD
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]