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The map label for this gene is yycF [H]

Identifier: 238917142

GI number: 238917142

Start: 1227344

End: 1228060

Strand: Reverse

Name: yycF [H]

Synonym: EUBELI_01214

Alternate gene names: 238917142

Gene position: 1228060-1227344 (Counterclockwise)

Preceding gene: 238917143

Following gene: 238917141

Centisome position: 57.27

GC content: 36.54

Gene sequence:

>717_bases
GTGTATAAAAAGAAAAAGGAGAAGGATATGGCAGGCAGAGTATTGGTTGTTGATGATGAGAAAATGATAGTTAAGGGACT
TAAATTCAGTCTTATGCAGGATTACAGTGAGGTTGACTGTGCATATGACGGGGAAGAGGCTCTTGAATATGTCAGAAACA
ACAAATATGACATTATCCTTCTCGATATTATGCTTCCTAAACTGGATGGATTATCAGTATGCCAGCAGATAAGGGAATTT
TCTAATGTTCCTATCATTATGCTGACAGCAAAAGGTGATGACATGGATAAAATTCTGGGACTTGATTATGGAGCGGATGA
TTATATAACAAAGCCTTTTAATATTCTTGAAGTGAAAGCAAGAATGAAAGCTATTTTAAGGCGTAATTCATCAATAACCC
AAAAGGAACAGAAAAGTAATGTGATAAAAGCAGGAGATATGAAAATTGACTGTGACAGCAGAAGTCTATATATTGCAGAT
AAGGAAATCAATCTTACTGCAAAAGAATTTGACTTGCTGGAGATACTTGCTGTTAATCCGGGAAAAGTGTATAGCCGTGA
CAACCTGTTAAAGGCTGTATGGGGACAGGATTATACAGGAGATGCAAGAACCGTGGATGTCCACATGAGAAGACTTAGGG
AAAAGATTGAGAATAATCCAAGTGAACCTAAGTATGTTCATACAAAGTGGGGAGTAGGATATTACTTTAATGTTTAA

Upstream 100 bases:

>100_bases
AATTACAGGAATACTAATGGCAGATTTGACAGGATTGAGGATATAATGAAGGTATCCGGGATAAAAGAGTCCGCATTTAA
TAAAATTAAGAATTATATAA

Downstream 100 bases:

>100_bases
TAAAAATAAAAATAAAAAGGAAATTAATCGTAGAAAAATCGTATGGATAAGAATTTTTGATAATTTTCTGAAATTTATAA
GAAGATATACAGTAATACAG

Product: two-component system OmpR family phosphate regulon response regulator OmpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MYKKKKEKDMAGRVLVVDDEKMIVKGLKFSLMQDYSEVDCAYDGEEALEYVRNNKYDIILLDIMLPKLDGLSVCQQIREF
SNVPIIMLTAKGDDMDKILGLDYGADDYITKPFNILEVKARMKAILRRNSSITQKEQKSNVIKAGDMKIDCDSRSLYIAD
KEINLTAKEFDLLEILAVNPGKVYSRDNLLKAVWGQDYTGDARTVDVHMRRLREKIENNPSEPKYVHTKWGVGYYFNV

Sequences:

>Translated_238_residues
MYKKKKEKDMAGRVLVVDDEKMIVKGLKFSLMQDYSEVDCAYDGEEALEYVRNNKYDIILLDIMLPKLDGLSVCQQIREF
SNVPIIMLTAKGDDMDKILGLDYGADDYITKPFNILEVKARMKAILRRNSSITQKEQKSNVIKAGDMKIDCDSRSLYIAD
KEINLTAKEFDLLEILAVNPGKVYSRDNLLKAVWGQDYTGDARTVDVHMRRLREKIENNPSEPKYVHTKWGVGYYFNV
>Mature_238_residues
MYKKKKEKDMAGRVLVVDDEKMIVKGLKFSLMQDYSEVDCAYDGEEALEYVRNNKYDIILLDIMLPKLDGLSVCQQIREF
SNVPIIMLTAKGDDMDKILGLDYGADDYITKPFNILEVKARMKAILRRNSSITQKEQKSNVIKAGDMKIDCDSRSLYIAD
KEINLTAKEFDLLEILAVNPGKVYSRDNLLKAVWGQDYTGDARTVDVHMRRLREKIENNPSEPKYVHTKWGVGYYFNV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=38.7665198237885, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=37.219730941704, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=39.0350877192982, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.9310344827586, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.6828193832599, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=39.9122807017544, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=35.6828193832599, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.4821428571429, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.7837837837838, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=32.3008849557522, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=35.3711790393013, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=32.6086956521739, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=33.0434782608696, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=29.7777777777778, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788724, Length=135, Percent_Identity=27.4074074074074, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=32.824427480916, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27412; Mature: 27412

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKKKKEKDMAGRVLVVDDEKMIVKGLKFSLMQDYSEVDCAYDGEEALEYVRNNKYDIIL
CCCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
LDIMLPKLDGLSVCQQIREFSNVPIIMLTAKGDDMDKILGLDYGADDYITKPFNILEVKA
EEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
RMKAILRRNSSITQKEQKSNVIKAGDMKIDCDSRSLYIADKEINLTAKEFDLLEILAVNP
HHHHHHHCCCCCCHHHHHCCCEEECCEEEECCCCEEEEECCCEEEEHHHCCEEEEEEECC
GKVYSRDNLLKAVWGQDYTGDARTVDVHMRRLREKIENNPSEPKYVHTKWGVGYYFNV
CCEECCCHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEC
>Mature Secondary Structure
MYKKKKEKDMAGRVLVVDDEKMIVKGLKFSLMQDYSEVDCAYDGEEALEYVRNNKYDIIL
CCCCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
LDIMLPKLDGLSVCQQIREFSNVPIIMLTAKGDDMDKILGLDYGADDYITKPFNILEVKA
EEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
RMKAILRRNSSITQKEQKSNVIKAGDMKIDCDSRSLYIADKEINLTAKEFDLLEILAVNP
HHHHHHHCCCCCCHHHHHCCCEEECCEEEECCCCEEEEECCCEEEEHHHCCEEEEEEECC
GKVYSRDNLLKAVWGQDYTGDARTVDVHMRRLREKIENNPSEPKYVHTKWGVGYYFNV
CCEECCCHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]