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The map label for this gene is rnr [H]

Identifier: 238917114

GI number: 238917114

Start: 1195970

End: 1198090

Strand: Reverse

Name: rnr [H]

Synonym: EUBELI_01185

Alternate gene names: 238917114

Gene position: 1198090-1195970 (Counterclockwise)

Preceding gene: 238917115

Following gene: 238917113

Centisome position: 55.88

GC content: 38.85

Gene sequence:

>2121_bases
ATGGAGAAGGATATATTTAAACAGCGAAGACAGATGCTTACTGATATGATTCTTAATAATGAACTGTATGTTCCAATGAA
AGCTAAAGAAATCGCTATGCTTCTCGATATTCCGAAAGCTAAGCGTTCAGAACTTATGGAAGTGCTTGACAGTCTTGTTG
CAGATGGAACAATAGGTGTATCAAAGAAGGGTAAGTATATGAAGCCTGAAAATGTAGCACTTGTCGGAACATTTGAAAGC
ACAAGCAGGGGCTTTGGTTTTGTAGTAATACCTGACAGGGAAGATGATATATTTGTTAAGGCTAATGACACGATGAATGC
TTTCTATCATGATAAAGTCAAGGTTGTGATAACTACTGAGAAGAATGGCGGTAAGAGGGCTGAAGGTAAGATTGTTGCTA
TTGTTGAGCATGAGGTTAAGGAAGTTGTCGGAACATTCCAGAAGAACAGAACGTATGGTTTTGTTATTCCTGATAATGCA
AAGATTAACTGTGATATATTTATACCGCAGGAATTCATGAATGGAGCGGTTGAAGGTTCTAAGGTAGTTGCTTCTATAAG
TGATTACGGCAGCCAGAGTAAGAATCCACAGGGGAAGGTCACAGAAGTACTTGGACATATAGATGACCCGGGTGTGGACA
TAATGTCTATTATCAAGGCATATGATTTACTAGTGGAGTTTCCTGAATCAGTTAAGAAGGCAATTAATGATATTCCTGAT
GTTGTCAGTGAAAAGGATAAGGCTGGACGAGTTGATTTAAGAAATGTTCAGATGGTTACTATAGATGGTGAGGATGCGAA
GGATTTAGATGATGCAGTATCTATCTCGAAAGAAGGACCTGTATATCATCTAGGTGTCCACATTGCGGATGTAAGTCATT
ATGTTACAGAGGGAAGTGCGCTGGATAAAGAGGCACTTAAACGAGGTACGAGTGTTTACCTTGTAGACCGTGTTATTCCA
ATGATACCGCATAAGTTATCTAATGGGATATGTTCACTTAATCAGGGAGAAGACAGACTGGCACTCAGCTGCCTTATGGA
TATTGATGAAAAGGGAAATATTGTTGGACATAGAATATGTGAAACTGTTATTAATGTAGACAGAAGAATGAGCTATACAA
GCGTAAAAAAGATTCTTGTAGATAATGATACTAATGAAATTATGAAGTATAAAGAGCTTGTTCCAATGTTTCATATGATG
GAAGAGGCTGCGGAGCTTCTTAGAAAGAAGAGATTTGCAAGAGGTTCGGTTGATTTTGATTTCCCTGAAAGTAAGATTAT
ACTTGATGAGAATGGCCACCCGACTGATATTAAGCCGTATGACAGAAATGTAGCAACTAAGATTATTGAAGATTTTATGC
TTGCTGCTAATGAAACTGTTGCAGAGGATTATTTCTGGCAGGATATGCCATTTCTATATAGAACTCATGAGAATCCTGAT
CCTGAAAAAATGCGTAAGTTAGCCACATTTATTAATAACTTTGGTTATACATTAAGACTTACTGATGATTTAAGACCTAA
GGAGATTCAGAAGCTTCTTTCTGAGATAGAGGGTTCTGATGCTGAGAATCTTATAAGCAGACTGACACTCCGCTCTATGA
AGAAAGCTAAGTATACTACTGAATGTGTAGGACATTTTGGACTCGCTGCCAAGTATTACTGTCATTTCACATCGCCTATC
AGAAGATATCCTGATCTCCAGATTCACAGAATTATCAAGGAGAATCTTCACGGAGGTTTAAGTCCTAAGAGAGCTGCCCA
TTATGATGCAATATTACCGGATGTTGCTGTCCAGACAAGTGCGATGGAGCGGCGTGCGGCAGATGCTGAAAGAGATACAG
ACAAGCTTAAAATGGCTGAGTATATGGAACAGTTTGTTGGAGAAACATTTGATGGAGTTGTTTCGGGTGTTACCGCGTGG
GGCGTATATGTTGAACTTCCAAACACTATCGAGGGCATGGTTTCTATCAATAATATGAAGGGATTCTATACATTTGACGA
GGAACACTATGAGATGGTAGGAGAACTTGGGAACAGAAGTTATAAGCTCGGACAGAAGGTTAAGGTTGTGGTTATAGGCA
CCGATAAGATACTAAGAACAATTGATTTTGCATTTGCATAG

Upstream 100 bases:

>100_bases
ACTCTTAAGAAACGGATAATTTCTTAAGAGTGTTTTTTACTTTTACGAGCAATCTGGTGAAATTCGGATATTTTAATGGT
AAGAAAGGGATATAAGGGAT

Downstream 100 bases:

>100_bases
AATAGAATGGAGACTGACATGGCATCAAAAACAAGCGCATCTGGAAACAGACTTATAGCGAACAATAAGAAAGCTTATTT
TGATTATTTTATAGAAGAGA

Product: exoribonuclease II

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MEKDIFKQRRQMLTDMILNNELYVPMKAKEIAMLLDIPKAKRSELMEVLDSLVADGTIGVSKKGKYMKPENVALVGTFES
TSRGFGFVVIPDREDDIFVKANDTMNAFYHDKVKVVITTEKNGGKRAEGKIVAIVEHEVKEVVGTFQKNRTYGFVIPDNA
KINCDIFIPQEFMNGAVEGSKVVASISDYGSQSKNPQGKVTEVLGHIDDPGVDIMSIIKAYDLLVEFPESVKKAINDIPD
VVSEKDKAGRVDLRNVQMVTIDGEDAKDLDDAVSISKEGPVYHLGVHIADVSHYVTEGSALDKEALKRGTSVYLVDRVIP
MIPHKLSNGICSLNQGEDRLALSCLMDIDEKGNIVGHRICETVINVDRRMSYTSVKKILVDNDTNEIMKYKELVPMFHMM
EEAAELLRKKRFARGSVDFDFPESKIILDENGHPTDIKPYDRNVATKIIEDFMLAANETVAEDYFWQDMPFLYRTHENPD
PEKMRKLATFINNFGYTLRLTDDLRPKEIQKLLSEIEGSDAENLISRLTLRSMKKAKYTTECVGHFGLAAKYYCHFTSPI
RRYPDLQIHRIIKENLHGGLSPKRAAHYDAILPDVAVQTSAMERRAADAERDTDKLKMAEYMEQFVGETFDGVVSGVTAW
GVYVELPNTIEGMVSINNMKGFYTFDEEHYEMVGELGNRSYKLGQKVKVVVIGTDKILRTIDFAFA

Sequences:

>Translated_706_residues
MEKDIFKQRRQMLTDMILNNELYVPMKAKEIAMLLDIPKAKRSELMEVLDSLVADGTIGVSKKGKYMKPENVALVGTFES
TSRGFGFVVIPDREDDIFVKANDTMNAFYHDKVKVVITTEKNGGKRAEGKIVAIVEHEVKEVVGTFQKNRTYGFVIPDNA
KINCDIFIPQEFMNGAVEGSKVVASISDYGSQSKNPQGKVTEVLGHIDDPGVDIMSIIKAYDLLVEFPESVKKAINDIPD
VVSEKDKAGRVDLRNVQMVTIDGEDAKDLDDAVSISKEGPVYHLGVHIADVSHYVTEGSALDKEALKRGTSVYLVDRVIP
MIPHKLSNGICSLNQGEDRLALSCLMDIDEKGNIVGHRICETVINVDRRMSYTSVKKILVDNDTNEIMKYKELVPMFHMM
EEAAELLRKKRFARGSVDFDFPESKIILDENGHPTDIKPYDRNVATKIIEDFMLAANETVAEDYFWQDMPFLYRTHENPD
PEKMRKLATFINNFGYTLRLTDDLRPKEIQKLLSEIEGSDAENLISRLTLRSMKKAKYTTECVGHFGLAAKYYCHFTSPI
RRYPDLQIHRIIKENLHGGLSPKRAAHYDAILPDVAVQTSAMERRAADAERDTDKLKMAEYMEQFVGETFDGVVSGVTAW
GVYVELPNTIEGMVSINNMKGFYTFDEEHYEMVGELGNRSYKLGQKVKVVVIGTDKILRTIDFAFA
>Mature_706_residues
MEKDIFKQRRQMLTDMILNNELYVPMKAKEIAMLLDIPKAKRSELMEVLDSLVADGTIGVSKKGKYMKPENVALVGTFES
TSRGFGFVVIPDREDDIFVKANDTMNAFYHDKVKVVITTEKNGGKRAEGKIVAIVEHEVKEVVGTFQKNRTYGFVIPDNA
KINCDIFIPQEFMNGAVEGSKVVASISDYGSQSKNPQGKVTEVLGHIDDPGVDIMSIIKAYDLLVEFPESVKKAINDIPD
VVSEKDKAGRVDLRNVQMVTIDGEDAKDLDDAVSISKEGPVYHLGVHIADVSHYVTEGSALDKEALKRGTSVYLVDRVIP
MIPHKLSNGICSLNQGEDRLALSCLMDIDEKGNIVGHRICETVINVDRRMSYTSVKKILVDNDTNEIMKYKELVPMFHMM
EEAAELLRKKRFARGSVDFDFPESKIILDENGHPTDIKPYDRNVATKIIEDFMLAANETVAEDYFWQDMPFLYRTHENPD
PEKMRKLATFINNFGYTLRLTDDLRPKEIQKLLSEIEGSDAENLISRLTLRSMKKAKYTTECVGHFGLAAKYYCHFTSPI
RRYPDLQIHRIIKENLHGGLSPKRAAHYDAILPDVAVQTSAMERRAADAERDTDKLKMAEYMEQFVGETFDGVVSGVTAW
GVYVELPNTIEGMVSINNMKGFYTFDEEHYEMVGELGNRSYKLGQKVKVVVIGTDKILRTIDFAFA

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=467, Percent_Identity=28.051391862955, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI190014623, Length=462, Percent_Identity=28.1385281385281, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI134288890, Length=508, Percent_Identity=28.9370078740157, Blast_Score=173, Evalue=7e-43,
Organism=Homo sapiens, GI219521928, Length=546, Percent_Identity=27.4725274725275, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI19115966, Length=546, Percent_Identity=27.4725274725275, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI156105695, Length=193, Percent_Identity=31.6062176165803, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI156105693, Length=132, Percent_Identity=34.0909090909091, Blast_Score=84, Evalue=6e-16,
Organism=Escherichia coli, GI87082383, Length=729, Percent_Identity=33.3333333333333, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1787542, Length=561, Percent_Identity=26.5597147950089, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17553506, Length=503, Percent_Identity=28.4294234592445, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=536, Percent_Identity=27.0522388059701, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324552, Length=536, Percent_Identity=28.7313432835821, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6320499, Length=440, Percent_Identity=25.4545454545455, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24649634, Length=473, Percent_Identity=30.6553911205074, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19922976, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24654597, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24654592, Length=434, Percent_Identity=30.4147465437788, Blast_Score=167, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 79632; Mature: 79632

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDIFKQRRQMLTDMILNNELYVPMKAKEIAMLLDIPKAKRSELMEVLDSLVADGTIGV
CCHHHHHHHHHHHHHHHHCCCEEEEECHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCC
SKKGKYMKPENVALVGTFESTSRGFGFVVIPDREDDIFVKANDTMNAFYHDKVKVVITTE
CCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCEEECEEEEEEEEC
KNGGKRAEGKIVAIVEHEVKEVVGTFQKNRTYGFVIPDNAKINCDIFIPQEFMNGAVEGS
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECHHHHCCCCCCH
KVVASISDYGSQSKNPQGKVTEVLGHIDDPGVDIMSIIKAYDLLVEFPESVKKAINDIPD
HHEEEHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSEKDKAGRVDLRNVQMVTIDGEDAKDLDDAVSISKEGPVYHLGVHIADVSHYVTEGSA
HHCCCCCCCCCEECCEEEEEECCCCCCCHHHHHCCCCCCCEEEEEEEEEHHHHHHHCCCC
LDKEALKRGTSVYLVDRVIPMIPHKLSNGICSLNQGEDRLALSCLMDIDEKGNIVGHRIC
CCHHHHHCCCEEEEHHHHHHHCCHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCHHHHHH
ETVINVDRRMSYTSVKKILVDNDTNEIMKYKELVPMFHMMEEAAELLRKKRFARGSVDFD
HHHHHHHHCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FPESKIILDENGHPTDIKPYDRNVATKIIEDFMLAANETVAEDYFWQDMPFLYRTHENPD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHEECCCCCC
PEKMRKLATFINNFGYTLRLTDDLRPKEIQKLLSEIEGSDAENLISRLTLRSMKKAKYTT
HHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ECVGHFGLAAKYYCHFTSPIRRYPDLQIHRIIKENLHGGLSPKRAAHYDAILPDVAVQTS
HHHHHHCCHHHEEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
AMERRAADAERDTDKLKMAEYMEQFVGETFDGVVSGVTAWGVYVELPNTIEGMVSINNMK
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCEEEECCC
GFYTFDEEHYEMVGELGNRSYKLGQKVKVVVIGTDKILRTIDFAFA
CEEEECHHHHHHHHHHCCCCEECCCEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MEKDIFKQRRQMLTDMILNNELYVPMKAKEIAMLLDIPKAKRSELMEVLDSLVADGTIGV
CCHHHHHHHHHHHHHHHHCCCEEEEECHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCC
SKKGKYMKPENVALVGTFESTSRGFGFVVIPDREDDIFVKANDTMNAFYHDKVKVVITTE
CCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCEEECEEEEEEEEC
KNGGKRAEGKIVAIVEHEVKEVVGTFQKNRTYGFVIPDNAKINCDIFIPQEFMNGAVEGS
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECHHHHCCCCCCH
KVVASISDYGSQSKNPQGKVTEVLGHIDDPGVDIMSIIKAYDLLVEFPESVKKAINDIPD
HHEEEHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSEKDKAGRVDLRNVQMVTIDGEDAKDLDDAVSISKEGPVYHLGVHIADVSHYVTEGSA
HHCCCCCCCCCEECCEEEEEECCCCCCCHHHHHCCCCCCCEEEEEEEEEHHHHHHHCCCC
LDKEALKRGTSVYLVDRVIPMIPHKLSNGICSLNQGEDRLALSCLMDIDEKGNIVGHRIC
CCHHHHHCCCEEEEHHHHHHHCCHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCHHHHHH
ETVINVDRRMSYTSVKKILVDNDTNEIMKYKELVPMFHMMEEAAELLRKKRFARGSVDFD
HHHHHHHHCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FPESKIILDENGHPTDIKPYDRNVATKIIEDFMLAANETVAEDYFWQDMPFLYRTHENPD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHEECCCCCC
PEKMRKLATFINNFGYTLRLTDDLRPKEIQKLLSEIEGSDAENLISRLTLRSMKKAKYTT
HHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ECVGHFGLAAKYYCHFTSPIRRYPDLQIHRIIKENLHGGLSPKRAAHYDAILPDVAVQTS
HHHHHHCCHHHEEEEECCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
AMERRAADAERDTDKLKMAEYMEQFVGETFDGVVSGVTAWGVYVELPNTIEGMVSINNMK
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCEEEECCC
GFYTFDEEHYEMVGELGNRSYKLGQKVKVVVIGTDKILRTIDFAFA
CEEEECHHHHHHHHHHCCCCEECCCEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]