Click here to switch to the map view.

The map label for this gene is apeA [H]

Identifier: 238917094

GI number: 238917094

Start: 1176026

End: 1177429

Strand: Reverse

Name: apeA [H]

Synonym: EUBELI_01164

Alternate gene names: 238917094

Gene position: 1177429-1176026 (Counterclockwise)

Preceding gene: 238917095

Following gene: 238917093

Centisome position: 54.91

GC content: 39.81

Gene sequence:

>1404_bases
ATGGAAAGAAAGAATGCATGGAAGAAATATTCAGACGAAGATAAGAACAATGTATTCACATTTGCAGATGAATATAAGAC
TTTTATATCTGAGTGTAAGACAGAAAGAGAATGTGTAAAAAAGGCTGTAGAATTGGCAAAGAAAGCCGGATACAGAGATT
TACAGGAGATAATAGCAGCCAATGAGACACTTAAAGCAGGCGATAAGGTATATGCCGTTAATATGAAGAAGGCAATAGTG
CTTTTTAATATTGGAAGTGAACCGATAAGTACCGGCATGAATATACTTGGGGCACATATTGATTCACCAAGACTTGATAT
CAAGCAGAATCCTATGTATGAAGATTCAGACCTGGTACTTCTTGATACACATTATTATGGAGGAATCAAGAAATACCAGT
GGGTAGCAATTCCTCTTGCACTTCATGGTGTTGTTGCATTAAAGAATGGCGAATGTGTTGAAGTTGTAATCGGAGAAGAT
GCTGACGATGCGGTTGTCGGAGTATCAGACCTTCTTATACACCTGGCTGCTAAACAGATGGAAAAGAAAGGAAGCTCGGT
GGTTGAGGGCGAGGACCTTGATATCCTTATAGGAAGCATGCCGGCAGCATCAGACAGTGATAATACAGATGAGGATAAGG
AAGAAAAGGAAGCAGTTAAGAAGAATATTCTTGCAATTCTTAAAGAAAAATATGGGATTGAAGAGGAAGATTTCTTATCA
GCAGAGCTTGAGGCTGTTCCGGCAGGACCTGCAAGAGATTATGGTCTGGACAGAAGCATGATTATGGGATATGGCCATGA
TGACAGAGTGTGTGCTTATCCGTCGCTTATTGCACTTCTTAATACACCACAGGTTAACAGAACAGGTGTGTGCATACTTG
TGGATAAAGAGGAGATAGGAAGCGTCGGCGCAACAGGTATGCATTCAAGATTCTTTGAAAATATGGTCGCAGAGGTTATG
GACAGATGTGGTGATTATTCAGAGCTTAAATTAAGAAGAGCGCTTGCTAATTCTTATATGTTATCATCAGATGTAAGTGC
AGCATATGACCCTAATTATGCATCAGTGTTTGAAAAGAAGAATTCAGCATTCTTTGGAAAAGGTATGGTATTTAACAAGT
ACACAGGTTCAAGAGGTAAGAGCGGTTCTAATGATGCTTCTGCTGAGTTCATTGGAAAGTTAAGAAAAGTTATGGATGAT
GCAGCTGTGTACTTCCAGATGGCAGAGCTTGGAAAGGTAGATGCAGGCGGTGGCGGAACAATTGCATATATCTTGGCTAA
TCTTGATATGAATGTAATCGACAGTGGAATTGCTGTACAGAATATGCATGCACCATACGAGGTAATAAGCAAGGCTGACC
TATATGAGACATTAAAGGGGTATGAAGCATTTTTACAGATGTAA

Upstream 100 bases:

>100_bases
GAGGCAGAGTTAGAGCTTGCAAGCGAAAGCTTTGATGCAGATAATCAGGAAGATTCTGATGGTCAGATAACATTAGGAAT
ATAGAAAGGAAGTTGACATT

Downstream 100 bases:

>100_bases
AATGTTTGTGTTAACGAAAGGACAATAATATGAAGTGGAATAAATATTCAATCCAGACAACTACAGATGCAGTTGATATG
ATAAGCAGCGCGCTTAATGA

Product: aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MERKNAWKKYSDEDKNNVFTFADEYKTFISECKTERECVKKAVELAKKAGYRDLQEIIAANETLKAGDKVYAVNMKKAIV
LFNIGSEPISTGMNILGAHIDSPRLDIKQNPMYEDSDLVLLDTHYYGGIKKYQWVAIPLALHGVVALKNGECVEVVIGED
ADDAVVGVSDLLIHLAAKQMEKKGSSVVEGEDLDILIGSMPAASDSDNTDEDKEEKEAVKKNILAILKEKYGIEEEDFLS
AELEAVPAGPARDYGLDRSMIMGYGHDDRVCAYPSLIALLNTPQVNRTGVCILVDKEEIGSVGATGMHSRFFENMVAEVM
DRCGDYSELKLRRALANSYMLSSDVSAAYDPNYASVFEKKNSAFFGKGMVFNKYTGSRGKSGSNDASAEFIGKLRKVMDD
AAVYFQMAELGKVDAGGGGTIAYILANLDMNVIDSGIAVQNMHAPYEVISKADLYETLKGYEAFLQM

Sequences:

>Translated_467_residues
MERKNAWKKYSDEDKNNVFTFADEYKTFISECKTERECVKKAVELAKKAGYRDLQEIIAANETLKAGDKVYAVNMKKAIV
LFNIGSEPISTGMNILGAHIDSPRLDIKQNPMYEDSDLVLLDTHYYGGIKKYQWVAIPLALHGVVALKNGECVEVVIGED
ADDAVVGVSDLLIHLAAKQMEKKGSSVVEGEDLDILIGSMPAASDSDNTDEDKEEKEAVKKNILAILKEKYGIEEEDFLS
AELEAVPAGPARDYGLDRSMIMGYGHDDRVCAYPSLIALLNTPQVNRTGVCILVDKEEIGSVGATGMHSRFFENMVAEVM
DRCGDYSELKLRRALANSYMLSSDVSAAYDPNYASVFEKKNSAFFGKGMVFNKYTGSRGKSGSNDASAEFIGKLRKVMDD
AAVYFQMAELGKVDAGGGGTIAYILANLDMNVIDSGIAVQNMHAPYEVISKADLYETLKGYEAFLQM
>Mature_467_residues
MERKNAWKKYSDEDKNNVFTFADEYKTFISECKTERECVKKAVELAKKAGYRDLQEIIAANETLKAGDKVYAVNMKKAIV
LFNIGSEPISTGMNILGAHIDSPRLDIKQNPMYEDSDLVLLDTHYYGGIKKYQWVAIPLALHGVVALKNGECVEVVIGED
ADDAVVGVSDLLIHLAAKQMEKKGSSVVEGEDLDILIGSMPAASDSDNTDEDKEEKEAVKKNILAILKEKYGIEEEDFLS
AELEAVPAGPARDYGLDRSMIMGYGHDDRVCAYPSLIALLNTPQVNRTGVCILVDKEEIGSVGATGMHSRFFENMVAEVM
DRCGDYSELKLRRALANSYMLSSDVSAAYDPNYASVFEKKNSAFFGKGMVFNKYTGSRGKSGSNDASAEFIGKLRKVMDD
AAVYFQMAELGKVDAGGGGTIAYILANLDMNVIDSGIAVQNMHAPYEVISKADLYETLKGYEAFLQM

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=476, Percent_Identity=24.3697478991597, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552916, Length=460, Percent_Identity=23.9130434782609, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322746, Length=464, Percent_Identity=22.8448275862069, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321905, Length=479, Percent_Identity=23.1732776617954, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51309; Mature: 51309

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKNAWKKYSDEDKNNVFTFADEYKTFISECKTERECVKKAVELAKKAGYRDLQEIIAA
CCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
NETLKAGDKVYAVNMKKAIVLFNIGSEPISTGMNILGAHIDSPRLDIKQNPMYEDSDLVL
CCHHCCCCEEEEEECCEEEEEEECCCCHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDTHYYGGIKKYQWVAIPLALHGVVALKNGECVEVVIGEDADDAVVGVSDLLIHLAAKQM
EECCCCCCCCEEEEEEEEEEHEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EKKGSSVVEGEDLDILIGSMPAASDSDNTDEDKEEKEAVKKNILAILKEKYGIEEEDFLS
HHCCCCEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AELEAVPAGPARDYGLDRSMIMGYGHDDRVCAYPSLIALLNTPQVNRTGVCILVDKEEIG
HHHHCCCCCCCCCCCCCCHHEEECCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEEHHHHC
SVGATGMHSRFFENMVAEVMDRCGDYSELKLRRALANSYMLSSDVSAAYDPNYASVFEKK
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
NSAFFGKGMVFNKYTGSRGKSGSNDASAEFIGKLRKVMDDAAVYFQMAELGKVDAGGGGT
CCCEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IAYILANLDMNVIDSGIAVQNMHAPYEVISKADLYETLKGYEAFLQM
EEEEEECCCHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERKNAWKKYSDEDKNNVFTFADEYKTFISECKTERECVKKAVELAKKAGYRDLQEIIAA
CCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
NETLKAGDKVYAVNMKKAIVLFNIGSEPISTGMNILGAHIDSPRLDIKQNPMYEDSDLVL
CCHHCCCCEEEEEECCEEEEEEECCCCHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDTHYYGGIKKYQWVAIPLALHGVVALKNGECVEVVIGEDADDAVVGVSDLLIHLAAKQM
EECCCCCCCCEEEEEEEEEEHEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EKKGSSVVEGEDLDILIGSMPAASDSDNTDEDKEEKEAVKKNILAILKEKYGIEEEDFLS
HHCCCCEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AELEAVPAGPARDYGLDRSMIMGYGHDDRVCAYPSLIALLNTPQVNRTGVCILVDKEEIG
HHHHCCCCCCCCCCCCCCHHEEECCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEEHHHHC
SVGATGMHSRFFENMVAEVMDRCGDYSELKLRRALANSYMLSSDVSAAYDPNYASVFEKK
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
NSAFFGKGMVFNKYTGSRGKSGSNDASAEFIGKLRKVMDDAAVYFQMAELGKVDAGGGGT
CCCEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IAYILANLDMNVIDSGIAVQNMHAPYEVISKADLYETLKGYEAFLQM
EEEEEECCCHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]