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The map label for this gene is prmA

Identifier: 238917093

GI number: 238917093

Start: 1175040

End: 1175996

Strand: Reverse

Name: prmA

Synonym: EUBELI_01163

Alternate gene names: 238917093

Gene position: 1175996-1175040 (Counterclockwise)

Preceding gene: 238917094

Following gene: 238917092

Centisome position: 54.85

GC content: 40.23

Gene sequence:

>957_bases
ATGAAGTGGAATAAATATTCAATCCAGACAACTACAGATGCAGTTGATATGATAAGCAGCGCGCTTAATGATATAGGAAT
TGAAGGTATCGAAATTGAGGATAATGTACAGCTTACTAAGGAAGAGGCTAAGTCAATGTTTGTAGATTTCATTCCTGACC
TTCCACCTGATGATGGCAGAGCTAAGGTTAATTTCTACATTGACAGTGAAGAAGATGATGGCTCAATGCTTGAAAAGGTT
AAGGCAGAACTTGAAGATTTAAGAATGTTTATTGATATTGGTGAGGGTACAATCACAGAATCAGAGACAGAGGATAAGGA
CTGGATTAATAACTGGAAGCAGTACTGGCATACATTTACAATAGGAGACTTATTCATTAAGCCTACATGGGAGCCGGAGA
CAGAGGAGATGAAGGGGCATGCTGTACTTAGCATTGACCCGGGAACAGCTTTCGGAACAGGTTCGCATGAGACTACAAGA
ATGGTTATAAAGCAGCTTCAGAAGTATGTTAAAGATGGTGATGAGGTGTTAGATGTCGGCTGTGGAAGCGGTATACTTTC
AGTAGTTGCATTAAAATATGGTGCAAAGCATGCATTTGGTACAGACCTCGACCCTAATGCAATTATTGCATCAGAGGAAA
ATGCAGAGCAGAACAATATAGATAAGAAGCAGCTTGAGGTTATTGAGGGTAATATCATTGATGATAAAGCTGTTAAAGAT
GCCTGTGGCTATGAGTGCTACGACATTGTGTGTGCCAATATCCTTGCAGACGTATTAGAGCCGCTTTCTACATGCATACA
TGAGCATATGAAGCACGGCGCTTACTTTATTACTTCCGGTATTATAGATACTAAGGAAAATGAGGTGGCAGAGGCATTTA
AGAAGAATCCTGAGTTAGAGATAGTTGAGATTAACCATGATGGCGAGTGGGTTAATATCACAGCAAGAAGGAAGTAG

Upstream 100 bases:

>100_bases
CATACGAGGTAATAAGCAAGGCTGACCTATATGAGACATTAAAGGGGTATGAAGCATTTTTACAGATGTAAAATGTTTGT
GTTAACGAAAGGACAATAAT

Downstream 100 bases:

>100_bases
TGTATGTATCATTTTTTTGCAGAGCATGAGAATATCCATGATTCATATATAGATATAGTTGGAAGTGATGTTAATCATAT
TAAGAATGTATTAAGATTCA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKWNKYSIQTTTDAVDMISSALNDIGIEGIEIEDNVQLTKEEAKSMFVDFIPDLPPDDGRAKVNFYIDSEEDDGSMLEKV
KAELEDLRMFIDIGEGTITESETEDKDWINNWKQYWHTFTIGDLFIKPTWEPETEEMKGHAVLSIDPGTAFGTGSHETTR
MVIKQLQKYVKDGDEVLDVGCGSGILSVVALKYGAKHAFGTDLDPNAIIASEENAEQNNIDKKQLEVIEGNIIDDKAVKD
ACGYECYDIVCANILADVLEPLSTCIHEHMKHGAYFITSGIIDTKENEVAEAFKKNPELEIVEINHDGEWVNITARRK

Sequences:

>Translated_318_residues
MKWNKYSIQTTTDAVDMISSALNDIGIEGIEIEDNVQLTKEEAKSMFVDFIPDLPPDDGRAKVNFYIDSEEDDGSMLEKV
KAELEDLRMFIDIGEGTITESETEDKDWINNWKQYWHTFTIGDLFIKPTWEPETEEMKGHAVLSIDPGTAFGTGSHETTR
MVIKQLQKYVKDGDEVLDVGCGSGILSVVALKYGAKHAFGTDLDPNAIIASEENAEQNNIDKKQLEVIEGNIIDDKAVKD
ACGYECYDIVCANILADVLEPLSTCIHEHMKHGAYFITSGIIDTKENEVAEAFKKNPELEIVEINHDGEWVNITARRK
>Mature_318_residues
MKWNKYSIQTTTDAVDMISSALNDIGIEGIEIEDNVQLTKEEAKSMFVDFIPDLPPDDGRAKVNFYIDSEEDDGSMLEKV
KAELEDLRMFIDIGEGTITESETEDKDWINNWKQYWHTFTIGDLFIKPTWEPETEEMKGHAVLSIDPGTAFGTGSHETTR
MVIKQLQKYVKDGDEVLDVGCGSGILSVVALKYGAKHAFGTDLDPNAIIASEENAEQNNIDKKQLEVIEGNIIDDKAVKD
ACGYECYDIVCANILADVLEPLSTCIHEHMKHGAYFITSGIIDTKENEVAEAFKKNPELEIVEINHDGEWVNITARRK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=320, Percent_Identity=32.5, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_EUBE2 (C4Z0Q0)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930610.1
- ProteinModelPortal:   C4Z0Q0
- GeneID:   7957707
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01163
- OMA:   IELNPGM
- ProtClustDB:   CLSK2506192
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35659; Mature: 35659

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWNKYSIQTTTDAVDMISSALNDIGIEGIEIEDNVQLTKEEAKSMFVDFIPDLPPDDGR
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
AKVNFYIDSEEDDGSMLEKVKAELEDLRMFIDIGEGTITESETEDKDWINNWKQYWHTFT
EEEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEE
IGDLFIKPTWEPETEEMKGHAVLSIDPGTAFGTGSHETTRMVIKQLQKYVKDGDEVLDVG
ECCEEEECCCCCCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
CGSGILSVVALKYGAKHAFGTDLDPNAIIASEENAEQNNIDKKQLEVIEGNIIDDKAVKD
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
ACGYECYDIVCANILADVLEPLSTCIHEHMKHGAYFITSGIIDTKENEVAEAFKKNPELE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEE
IVEINHDGEWVNITARRK
EEEECCCCCEEEEEECCC
>Mature Secondary Structure
MKWNKYSIQTTTDAVDMISSALNDIGIEGIEIEDNVQLTKEEAKSMFVDFIPDLPPDDGR
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
AKVNFYIDSEEDDGSMLEKVKAELEDLRMFIDIGEGTITESETEDKDWINNWKQYWHTFT
EEEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEE
IGDLFIKPTWEPETEEMKGHAVLSIDPGTAFGTGSHETTRMVIKQLQKYVKDGDEVLDVG
ECCEEEECCCCCCHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECC
CGSGILSVVALKYGAKHAFGTDLDPNAIIASEENAEQNNIDKKQLEVIEGNIIDDKAVKD
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
ACGYECYDIVCANILADVLEPLSTCIHEHMKHGAYFITSGIIDTKENEVAEAFKKNPELE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEE
IVEINHDGEWVNITARRK
EEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA