BacMap

Definition	Eubacterium eligens ATCC 27750 chromosome, complete genome.
Accession	NC_012778
Length	2,144,190

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The map label for this gene is idnO [H]

Identifier: 238917040

GI number: 238917040

Start: 1119750

End: 1120547

Strand: Reverse

Name: idnO [H]

Synonym: EUBELI_01110

Alternate gene names: 238917040

Gene position: 1120547-1119750 (Counterclockwise)

Preceding gene: 238917041

Following gene: 238917039

Centisome position: 52.26

GC content: 42.48

Gene sequence:

>798_bases
ATGTCAGTTAATTTTTCACTTGAAGGTAAGATTGCATTTGTAACTGGTGCATCATATGGTATCGGCTTCGCTATCGCTAG
TGGTATGGCTAAGGCTGGTGCAAAAATCGTTTTCAACGATATTAAGCAGGAATTAGTAGATAAGGGATTAGCAGCTTATA
AGGAAGCTGGTATCGACGCTCACGGATATGTTTGCGACGTTACTAACGAAGAAGCTGTTAACGCTACTGTAGAGAAAATC
ACAAAGGAAGTTGGACCAATCGATATCCTCGTAAACAACGCTGGTATCATTAAGAGAATTCCTATGTGCGAGATGACAGC
TGCTGAGTTCAGACAGGTTATCGACGTAGATCTTAACGCACCATTCATCGTATCAAAGGCAGTAATTCCTTCAATGATCG
AAAGAGGACATGGTAAGATCATCAACATCTGCTCAATGATGTCAGAATTAGGCCGTGAGACAGTATCAGCTTACGCTGCT
GCTAAGGGTGGTCTTAAGATGCTTACAAGAAATATTTGTTCTGAGTATGGTAAGTACAATATCCAGTGTAATGGTATTGG
ACCTGGTTACATCGAGACACCTCAGACAGCTCCATTAAGAGAGAGACAGCCAGATGGATCAAGACATCCATTCGACTCAT
TCATCGTTGCAAAGACACCAGCAGAGAGATGGTTAAAGCCAGAAGAATTAGCTGGTCCAGCTGTATTCCTTGCTTCAGAA
GCATCAGATGCAGTTAATGGACACATCCTCTATGTAGATGGTGGTATCCTTGCATACATCGGCAAGCAGCCACAGTAA

Upstream 100 bases:

>100_bases
ATGAAGGATTTAAAGTAATCCGTCAGTACATATTTTACTAAGGAATGTAACCTGTAGAGGGTTTCATTTATAAATTATTA
TTAGGAAAAGGAGAATTAAA

Downstream 100 bases:

>100_bases
TCGCGGAGTACAAGCGCAGTGCGCGAATGATAGAAGAACCAGAGTGCAAGTTTACTTGTAACTCTGGTTCTTTTGTTATT
CGCATAGAGCGCGACAGCGC

Product: gluconate 5-dehydrogenase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSVNFSLEGKIAFVTGASYGIGFAIASGMAKAGAKIVFNDIKQELVDKGLAAYKEAGIDAHGYVCDVTNEEAVNATVEKI
TKEVGPIDILVNNAGIIKRIPMCEMTAAEFRQVIDVDLNAPFIVSKAVIPSMIERGHGKIINICSMMSELGRETVSAYAA
AKGGLKMLTRNICSEYGKYNIQCNGIGPGYIETPQTAPLRERQPDGSRHPFDSFIVAKTPAERWLKPEELAGPAVFLASE
ASDAVNGHILYVDGGILAYIGKQPQ

Sequences:

>Translated_265_residues
MSVNFSLEGKIAFVTGASYGIGFAIASGMAKAGAKIVFNDIKQELVDKGLAAYKEAGIDAHGYVCDVTNEEAVNATVEKI
TKEVGPIDILVNNAGIIKRIPMCEMTAAEFRQVIDVDLNAPFIVSKAVIPSMIERGHGKIINICSMMSELGRETVSAYAA
AKGGLKMLTRNICSEYGKYNIQCNGIGPGYIETPQTAPLRERQPDGSRHPFDSFIVAKTPAERWLKPEELAGPAVFLASE
ASDAVNGHILYVDGGILAYIGKQPQ
>Mature_264_residues
SVNFSLEGKIAFVTGASYGIGFAIASGMAKAGAKIVFNDIKQELVDKGLAAYKEAGIDAHGYVCDVTNEEAVNATVEKIT
KEVGPIDILVNNAGIIKRIPMCEMTAAEFRQVIDVDLNAPFIVSKAVIPSMIERGHGKIINICSMMSELGRETVSAYAAA
KGGLKMLTRNICSEYGKYNIQCNGIGPGYIETPQTAPLRERQPDGSRHPFDSFIVAKTPAERWLKPEELAGPAVFLASEA
SDAVNGHILYVDGGILAYIGKQPQ

Specific function: Catalyzes a reversible reduction of 5-ketoglutanate to form D-gluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=31.7829457364341, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=30.3643724696356, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=30.8900523560209, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=28.4615384615385, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.1023622047244, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=31.304347826087, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI142976729, Length=200, Percent_Identity=28, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=30.5882352941176, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=28.4584980237154, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.5140562248996, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=32.0574162679426, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=32.4022346368715, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=28.6274509803922, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.413612565445, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI40807363, Length=155, Percent_Identity=32.258064516129, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=28.6274509803922, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=27.7310924369748, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4504505, Length=268, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI25282469, Length=185, Percent_Identity=26.4864864864865, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=265, Percent_Identity=27.5471698113208, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40254986, Length=191, Percent_Identity=32.9842931937173, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=27.6515151515151, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI310128830, Length=144, Percent_Identity=29.8611111111111, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI310115468, Length=144, Percent_Identity=29.8611111111111, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI210032112, Length=191, Percent_Identity=26.1780104712042, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI31542939, Length=253, Percent_Identity=24.901185770751, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19743808, Length=196, Percent_Identity=27.0408163265306, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=48.828125, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=40.5405405405405, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=39.2996108949416, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=36.7588932806324, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=34.251968503937, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=26.6409266409266, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=29.2490118577075, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=213, Percent_Identity=27.2300469483568, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=28.4584980237154, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.3846153846154, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787526, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=25.8823529411765, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=27.4131274131274, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.6772908366534, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=29.6875, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=29.6992481203008, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=28.2178217821782, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=28.5, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=32.48730964467, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=29.8429319371728, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=27.3062730627306, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=216, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=27.4074074074074, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=25.968992248062, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=27.6363636363636, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=285, Percent_Identity=27.719298245614, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=24.2063492063492, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=24.7368421052632, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=25.830258302583, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=27.6264591439689, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=212, Percent_Identity=23.5849056603774, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.7924528301887, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=25.2788104089219, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=26.0377358490566, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=24.9084249084249, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=24, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.4131274131274, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=23.7918215613383, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=201, Percent_Identity=35.8208955223881, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=25.5905511811024, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320089, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=34.2205323193916, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=28.2352941176471, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640492, Length=240, Percent_Identity=30.4166666666667, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581726, Length=213, Percent_Identity=30.0469483568075, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=28.125, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221510726, Length=189, Percent_Identity=30.6878306878307, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=32.1052631578947, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.7179487179487, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=28.2722513089005, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=26.8482490272374, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641232, Length=227, Percent_Identity=29.9559471365639, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=28.1407035175879, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=26.4591439688716, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648693, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355889, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=25.0950570342205, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=25.2941176470588, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648944, Length=200, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 28384; Mature: 28253

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNFSLEGKIAFVTGASYGIGFAIASGMAKAGAKIVFNDIKQELVDKGLAAYKEAGIDA
CCCEEEECCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
HGYVCDVTNEEAVNATVEKITKEVGPIDILVNNAGIIKRIPMCEMTAAEFRQVIDVDLNA
CCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCHHEECCCCHHHHHHHHHHHHCCCCC
PFIVSKAVIPSMIERGHGKIINICSMMSELGRETVSAYAAAKGGLKMLTRNICSEYGKYN
CEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEE
IQCNGIGPGYIETPQTAPLRERQPDGSRHPFDSFIVAKTPAERWLKPEELAGPAVFLASE
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHCCCHHHHCCCEEEEECC
ASDAVNGHILYVDGGILAYIGKQPQ
CCCCCCCEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
SVNFSLEGKIAFVTGASYGIGFAIASGMAKAGAKIVFNDIKQELVDKGLAAYKEAGIDA
CCEEEECCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
HGYVCDVTNEEAVNATVEKITKEVGPIDILVNNAGIIKRIPMCEMTAAEFRQVIDVDLNA
CCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCHHEECCCCHHHHHHHHHHHHCCCCC
PFIVSKAVIPSMIERGHGKIINICSMMSELGRETVSAYAAAKGGLKMLTRNICSEYGKYN
CEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEE
IQCNGIGPGYIETPQTAPLRERQPDGSRHPFDSFIVAKTPAERWLKPEELAGPAVFLASE
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHCCCHHHHCCCEEEEECC
ASDAVNGHILYVDGGILAYIGKQPQ
CCCCCCCEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]