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The map label for this gene is xseA [H]

Identifier: 238917017

GI number: 238917017

Start: 1100457

End: 1101668

Strand: Reverse

Name: xseA [H]

Synonym: EUBELI_01087

Alternate gene names: 238917017

Gene position: 1101668-1100457 (Counterclockwise)

Preceding gene: 238917018

Following gene: 238917016

Centisome position: 51.38

GC content: 39.52

Gene sequence:

>1212_bases
ATGGCTGGAGTATATACTGTAAAGCAGGTGAATTCCTATATTAAGAATATGTTTAAGCAGGATTTTCTGCTTAACTCGGT
TTCTGTTAAGGGGGAGATATCTAATTGCAAGTATCATACCTCCGGTCATATTTATTTTACTTTAAAGGATGCTGATGCGG
CACTTTCTGTCATTATGTTTGCAAGTCAGGCTGCAAGGCTTAGCTTTAAGTTAAAAGATGGAATGTCTGTTGTTGTTTCA
GGAAGAGTAGATGTATTTGACGCTGCCGGTAAATACCAGCTGTATGCCAATACTGTACAGCAAGAAGGTATTGGCGAACT
GTATCAGAAGTATGAACAGCTTAAGCAGTATTATGAAGATATGGGCTACTTTGCTAAAGAGTATAAAAGACCGCTTCCTG
CATTTACCAGGAAATTAGGTGTTGTAACATCCAAGACAGGTGCAGCAGTTCAGGATATTATGAACATTTCCAAAAGGCGT
AACCCTTATATCCAGATTGTACTTTATCCTGCATATGTTCAGGGAGAACATGCAAAGCAGTCAATTGTAAGCGGAATTAC
CAGACTTGATAAGATGGGGCTTGACTGTATTATAGTAGGACGAGGCGGCGGTTCAATAGAAGATTTATGGGCTTTTAATG
AACCTGAGGTTGTAGAGGCTGTGTTTAACGCTTCAACACCAGTAATATCAGCAGTAGGACATGAGACAGATTTTACACTC
ACTGATTTTGTAGCTGATATGAGAGCACCCACACCTTCTGCTGCGGCAGAGCTTGCTGTTACAGAGGTAGCGGCTGTTGA
AAACAGGATATATGAATATGAAAGACGGTTAAAGCAGCAGATGATGTATTCGTTGTCTGCAAAAAGAGACTATCTGGAAA
GATTAAAGCTACAGATGGAATATCTTAACCCTGTCAATCAGATATATGATAAAAGACAGCGGCTTATGAATATAGAAGAT
AAGCTGAACATGTTAATAAAAAGATGTGCGGCTGAAAATAGAAACAGACTTCGTCTGTATGCTTCGAAACTTGAGGGGTT
AAGTCCTTTGAAAAAGCTTGATATGGGCTATGGCTATATTGAGAATTCTGAAGGTAACAGAATTGTATCAGCCGGTCAGG
TGTCGTCAGATGACGAGATTACAGTTTATCTTAAAGATGGAAGCATCAGATCTAAGGTTATTGAGGTAGGGGAAGCATGG
CAAAAACATTAG

Upstream 100 bases:

>100_bases
GAAGTATGGCTCGGCTGACAGCACAGCAGCTTTTGTTAATGGTGTATTAGGCAAGTTAATTAAAGAGTAATGCAGTTTTT
TGCATGTAAAGTGAGGATAT

Downstream 100 bases:

>100_bases
AACAGTCATTTAAAAGACTTGAAGAAATAATTGCACAGATGGAAAAATCAGACACAACACTTGATGCATCATTTAAAATG
TATCAGGAGGGGATGAAGCT

Product: exodeoxyribonuclease VII

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAGVYTVKQVNSYIKNMFKQDFLLNSVSVKGEISNCKYHTSGHIYFTLKDADAALSVIMFASQAARLSFKLKDGMSVVVS
GRVDVFDAAGKYQLYANTVQQEGIGELYQKYEQLKQYYEDMGYFAKEYKRPLPAFTRKLGVVTSKTGAAVQDIMNISKRR
NPYIQIVLYPAYVQGEHAKQSIVSGITRLDKMGLDCIIVGRGGGSIEDLWAFNEPEVVEAVFNASTPVISAVGHETDFTL
TDFVADMRAPTPSAAAELAVTEVAAVENRIYEYERRLKQQMMYSLSAKRDYLERLKLQMEYLNPVNQIYDKRQRLMNIED
KLNMLIKRCAAENRNRLRLYASKLEGLSPLKKLDMGYGYIENSEGNRIVSAGQVSSDDEITVYLKDGSIRSKVIEVGEAW
QKH

Sequences:

>Translated_403_residues
MAGVYTVKQVNSYIKNMFKQDFLLNSVSVKGEISNCKYHTSGHIYFTLKDADAALSVIMFASQAARLSFKLKDGMSVVVS
GRVDVFDAAGKYQLYANTVQQEGIGELYQKYEQLKQYYEDMGYFAKEYKRPLPAFTRKLGVVTSKTGAAVQDIMNISKRR
NPYIQIVLYPAYVQGEHAKQSIVSGITRLDKMGLDCIIVGRGGGSIEDLWAFNEPEVVEAVFNASTPVISAVGHETDFTL
TDFVADMRAPTPSAAAELAVTEVAAVENRIYEYERRLKQQMMYSLSAKRDYLERLKLQMEYLNPVNQIYDKRQRLMNIED
KLNMLIKRCAAENRNRLRLYASKLEGLSPLKKLDMGYGYIENSEGNRIVSAGQVSSDDEITVYLKDGSIRSKVIEVGEAW
QKH
>Mature_402_residues
AGVYTVKQVNSYIKNMFKQDFLLNSVSVKGEISNCKYHTSGHIYFTLKDADAALSVIMFASQAARLSFKLKDGMSVVVSG
RVDVFDAAGKYQLYANTVQQEGIGELYQKYEQLKQYYEDMGYFAKEYKRPLPAFTRKLGVVTSKTGAAVQDIMNISKRRN
PYIQIVLYPAYVQGEHAKQSIVSGITRLDKMGLDCIIVGRGGGSIEDLWAFNEPEVVEAVFNASTPVISAVGHETDFTLT
DFVADMRAPTPSAAAELAVTEVAAVENRIYEYERRLKQQMMYSLSAKRDYLERLKLQMEYLNPVNQIYDKRQRLMNIEDK
LNMLIKRCAAENRNRLRLYASKLEGLSPLKKLDMGYGYIENSEGNRIVSAGQVSSDDEITVYLKDGSIRSKVIEVGEAWQ
KH

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=35.4691075514874, Blast_Score=278, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45516; Mature: 45385

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVYTVKQVNSYIKNMFKQDFLLNSVSVKGEISNCKYHTSGHIYFTLKDADAALSVIMF
CCCCHHHHHHHHHHHHHHHHHHHHHCEEECEECCCCEEECCCEEEEEEECCHHHHHHHHH
ASQAARLSFKLKDGMSVVVSGRVDVFDAAGKYQLYANTVQQEGIGELYQKYEQLKQYYED
HHHHHHEEEEECCCCEEEEECCEEEEECCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHH
MGYFAKEYKRPLPAFTRKLGVVTSKTGAAVQDIMNISKRRNPYIQIVLYPAYVQGEHAKQ
HHHHHHHHCCCCHHHHHHHCCEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHH
SIVSGITRLDKMGLDCIIVGRGGGSIEDLWAFNEPEVVEAVFNASTPVISAVGHETDFTL
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCHH
TDFVADMRAPTPSAAAELAVTEVAAVENRIYEYERRLKQQMMYSLSAKRDYLERLKLQME
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLNPVNQIYDKRQRLMNIEDKLNMLIKRCAAENRNRLRLYASKLEGLSPLKKLDMGYGYI
HHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHCCCCEE
ENSEGNRIVSAGQVSSDDEITVYLKDGSIRSKVIEVGEAWQKH
ECCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGVYTVKQVNSYIKNMFKQDFLLNSVSVKGEISNCKYHTSGHIYFTLKDADAALSVIMF
CCCHHHHHHHHHHHHHHHHHHHHHCEEECEECCCCEEECCCEEEEEEECCHHHHHHHHH
ASQAARLSFKLKDGMSVVVSGRVDVFDAAGKYQLYANTVQQEGIGELYQKYEQLKQYYED
HHHHHHEEEEECCCCEEEEECCEEEEECCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHH
MGYFAKEYKRPLPAFTRKLGVVTSKTGAAVQDIMNISKRRNPYIQIVLYPAYVQGEHAKQ
HHHHHHHHCCCCHHHHHHHCCEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHH
SIVSGITRLDKMGLDCIIVGRGGGSIEDLWAFNEPEVVEAVFNASTPVISAVGHETDFTL
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHCCCCCEEECCCCCCCCHH
TDFVADMRAPTPSAAAELAVTEVAAVENRIYEYERRLKQQMMYSLSAKRDYLERLKLQME
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLNPVNQIYDKRQRLMNIEDKLNMLIKRCAAENRNRLRLYASKLEGLSPLKKLDMGYGYI
HHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHCCCCEE
ENSEGNRIVSAGQVSSDDEITVYLKDGSIRSKVIEVGEAWQKH
ECCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA