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The map label for this gene is coaE [H]

Identifier: 238917002

GI number: 238917002

Start: 1083297

End: 1083887

Strand: Reverse

Name: coaE [H]

Synonym: EUBELI_01071

Alternate gene names: 238917002

Gene position: 1083887-1083297 (Counterclockwise)

Preceding gene: 238917003

Following gene: 238917001

Centisome position: 50.55

GC content: 36.04

Gene sequence:

>591_bases
ATGAAAGTTATTGGAATCACAGGTGGTGTAGGAGCAGGAAAATCTTCTGTTCTTGCACTCCTTAAAGAAATGTGTTCCTG
CGACATTATACAGGCAGACCTTGTTGCAAGAAATATATACCAATCAGGCAATATTGGATTTAAAAAGGTCGTTGATATAT
TCGGGGAGCAGATTGTAGGAGAGAATGGAGAGATAAACAGACCTCTTCTCGCAGATATTATATTTAAGAACCCTAATAAG
AGAATCGTTCTTAACAGCATAATTCATCCTCTTGTAAAACAAGAGATTATTAATCAGATTAATAATCATAAGATAGCAGG
TGATGTTGATTACTGTTTTGTTGAGGCAGCACTGCTTATTGAAGATCACTATGATATATTCATGGATGAGATATGGTATA
TATATGTTTCGGAAGATGAGAGAAGAAAAAGACTTGCTGCTTCAAGAGGCTATTCTGATGAAAAGATATCAGACATATTT
AAAAGCCAGCTATCTGATGCTGAGTTCAGAAAGCATGCAGATAAAGTGATTGATAATGGCGCAGATATAGAAAAAACACG
CGCCCAGCTTGAGATTATGCTTGGAATATGA

Upstream 100 bases:

>100_bases
TAAAGCAGATTATGCTTGATGGAATGAAGAATGCAGTAAGCCTTAAGGTACCTCTTGAGGTAGATTTAAAGGAAGGAAAA
GACTGGCTGGAGGCACACTG

Downstream 100 bases:

>100_bases
TACATTTATACATAATTTGTTTATTCTAGAGGTAGGGTATGGATAATACACAGTCAAGAAAAGAGACCCTTGTTTTTGGT
CTTGATATAGGAACAAGAAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKVIGITGGVGAGKSSVLALLKEMCSCDIIQADLVARNIYQSGNIGFKKVVDIFGEQIVGENGEINRPLLADIIFKNPNK
RIVLNSIIHPLVKQEIINQINNHKIAGDVDYCFVEAALLIEDHYDIFMDEIWYIYVSEDERRKRLAASRGYSDEKISDIF
KSQLSDAEFRKHADKVIDNGADIEKTRAQLEIMLGI

Sequences:

>Translated_196_residues
MKVIGITGGVGAGKSSVLALLKEMCSCDIIQADLVARNIYQSGNIGFKKVVDIFGEQIVGENGEINRPLLADIIFKNPNK
RIVLNSIIHPLVKQEIINQINNHKIAGDVDYCFVEAALLIEDHYDIFMDEIWYIYVSEDERRKRLAASRGYSDEKISDIF
KSQLSDAEFRKHADKVIDNGADIEKTRAQLEIMLGI
>Mature_196_residues
MKVIGITGGVGAGKSSVLALLKEMCSCDIIQADLVARNIYQSGNIGFKKVVDIFGEQIVGENGEINRPLLADIIFKNPNK
RIVLNSIIHPLVKQEIINQINNHKIAGDVDYCFVEAALLIEDHYDIFMDEIWYIYVSEDERRKRLAASRGYSDEKISDIF
KSQLSDAEFRKHADKVIDNGADIEKTRAQLEIMLGI

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=28.8659793814433, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=28.8659793814433, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110227607, Length=191, Percent_Identity=26.7015706806283, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI205277394, Length=191, Percent_Identity=26.7015706806283, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110227605, Length=191, Percent_Identity=26.7015706806283, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110227603, Length=191, Percent_Identity=26.7015706806283, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110227601, Length=191, Percent_Identity=26.7015706806283, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786292, Length=177, Percent_Identity=26.5536723163842, Blast_Score=77, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25143409, Length=189, Percent_Identity=26.4550264550265, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=195, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24658602, Length=190, Percent_Identity=28.4210526315789, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24644728, Length=189, Percent_Identity=26.4550264550265, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22013; Mature: 22013

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIGITGGVGAGKSSVLALLKEMCSCDIIQADLVARNIYQSGNIGFKKVVDIFGEQIVG
CEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ENGEINRPLLADIIFKNPNKRIVLNSIIHPLVKQEIINQINNHKIAGDVDYCFVEAALLI
CCCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EDHYDIFMDEIWYIYVSEDERRKRLAASRGYSDEKISDIFKSQLSDAEFRKHADKVIDNG
HHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
ADIEKTRAQLEIMLGI
CCHHHHHHHHEEEECC
>Mature Secondary Structure
MKVIGITGGVGAGKSSVLALLKEMCSCDIIQADLVARNIYQSGNIGFKKVVDIFGEQIVG
CEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
ENGEINRPLLADIIFKNPNKRIVLNSIIHPLVKQEIINQINNHKIAGDVDYCFVEAALLI
CCCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EDHYDIFMDEIWYIYVSEDERRKRLAASRGYSDEKISDIFKSQLSDAEFRKHADKVIDNG
HHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
ADIEKTRAQLEIMLGI
CCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA