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The map label for this gene is lepB [H]

Identifier: 238916979

GI number: 238916979

Start: 1060235

End: 1060792

Strand: Reverse

Name: lepB [H]

Synonym: EUBELI_01048

Alternate gene names: 238916979

Gene position: 1060792-1060235 (Counterclockwise)

Preceding gene: 238916980

Following gene: 238916978

Centisome position: 49.47

GC content: 34.59

Gene sequence:

>558_bases
ATGAGATTTTTTCAGAGAAGATATCAGGAAAATACTACATTGCTTAATATATGCAAATATATAGCAGATGTATGTGTTGT
AATAGTACTTGCTTATGTTCTGGTTACATTCATATGCTGCCGTTCTACAGTTGTTGGTAATTCTATGGAGGAAACGCTGT
CTAATGATAACACTGTTCTTATAAACAGAATATCATATGCATTTAATGGACCTAAGCGATTTGACTGTATAGCTTTCGAA
CAGGATTCTGTTGATTCCTCTAAGATATACATAAAGAGAGTAGTTGGACTTCCAGGGGAAACAGTCCAGATAAAGGATGG
CAGGGTATATATTAATGATGTACAGCTTGATGATTATGTTGATACGACAATACTTACTCCAGGTGTAGCTGCCAATCCTT
ATAAACTTGCTGATGATGAATACTTTGTACTTGGAGATAATCGTAATAATAGTGAGGATAGCCGTTTTGCCAGTGTTGGA
ATGGTTAAACGTAAGAATGTTGTAGGAAAAGTATGGATGGTAATAGAACCGTTTGATTCATTTGGTTTTGTTAAATAA

Upstream 100 bases:

>100_bases
GGTTAAGGAATTAGTTAGATAATTTTGTTATTCACGGTAAGGGACATTTGAAAAAATGTCCCTTTACTTATATATAAGCG
ACAGGAAAGGTCGGAATATT

Downstream 100 bases:

>100_bases
TGGAGATATATATGGAAGAGAAGAAAAGAGCCATTAACTGGTATCCTGGTCATATGACTAAGGCCAGAAGAATGATGGAA
GAAGATATAAAGCTTGTTGA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRFFQRRYQENTTLLNICKYIADVCVVIVLAYVLVTFICCRSTVVGNSMEETLSNDNTVLINRISYAFNGPKRFDCIAFE
QDSVDSSKIYIKRVVGLPGETVQIKDGRVYINDVQLDDYVDTTILTPGVAANPYKLADDEYFVLGDNRNNSEDSRFASVG
MVKRKNVVGKVWMVIEPFDSFGFVK

Sequences:

>Translated_185_residues
MRFFQRRYQENTTLLNICKYIADVCVVIVLAYVLVTFICCRSTVVGNSMEETLSNDNTVLINRISYAFNGPKRFDCIAFE
QDSVDSSKIYIKRVVGLPGETVQIKDGRVYINDVQLDDYVDTTILTPGVAANPYKLADDEYFVLGDNRNNSEDSRFASVG
MVKRKNVVGKVWMVIEPFDSFGFVK
>Mature_185_residues
MRFFQRRYQENTTLLNICKYIADVCVVIVLAYVLVTFICCRSTVVGNSMEETLSNDNTVLINRISYAFNGPKRFDCIAFE
QDSVDSSKIYIKRVVGLPGETVQIKDGRVYINDVQLDDYVDTTILTPGVAANPYKLADDEYFVLGDNRNNSEDSRFASVG
MVKRKNVVGKVWMVIEPFDSFGFVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21003; Mature: 21003

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFQRRYQENTTLLNICKYIADVCVVIVLAYVLVTFICCRSTVVGNSMEETLSNDNTVL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEE
INRISYAFNGPKRFDCIAFEQDSVDSSKIYIKRVVGLPGETVQIKDGRVYINDVQLDDYV
EEEEEEEECCCCCEEEEEECCCCCCCHHEEEEEEECCCCCEEEEECCEEEEEEEEECCCC
DTTILTPGVAANPYKLADDEYFVLGDNRNNSEDSRFASVGMVKRKNVVGKVWMVIEPFDS
CCEEECCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCC
FGFVK
CCCCC
>Mature Secondary Structure
MRFFQRRYQENTTLLNICKYIADVCVVIVLAYVLVTFICCRSTVVGNSMEETLSNDNTVL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEE
INRISYAFNGPKRFDCIAFEQDSVDSSKIYIKRVVGLPGETVQIKDGRVYINDVQLDDYV
EEEEEEEECCCCCEEEEEECCCCCCCHHEEEEEEECCCCCEEEEECCEEEEEEEEECCCC
DTTILTPGVAANPYKLADDEYFVLGDNRNNSEDSRFASVGMVKRKNVVGKVWMVIEPFDS
CCEEECCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCC
FGFVK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]