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The map label for this gene is rnhB [H]

Identifier: 238916977

GI number: 238916977

Start: 1058647

End: 1059303

Strand: Reverse

Name: rnhB [H]

Synonym: EUBELI_01046

Alternate gene names: 238916977

Gene position: 1059303-1058647 (Counterclockwise)

Preceding gene: 238916978

Following gene: 238916976

Centisome position: 49.4

GC content: 34.86

Gene sequence:

>657_bases
ATGACACTTAAAGAGGAACGTGAACTTAAAAAAGCAGCAAAGCTGGAGGCTGAGAAACAGCGTATTGAAGCTATGCGTGA
ATATGAAGAAATGTATGATACATTTTCTTATATATGTGGAATAGATGAGGCTGGAAGAGGACCGCTTGCAGGTCCTGTTG
TTGCAGGTGCAGTAATTCTTCCTAAAGGAAAAAGGATTCTTTATGTAAATGATTCCAAGAAATTAAGTGAGAAAAAAAGA
GATGAACTTTTTGATGTTATAAAAGAAGAAGCACTTTCATACGGAATTGGAATTGTATCTCCTGAAAGAATTGATGAGAT
TAATATATTGCAGGCAACTTATGAAGCAATGCACGAAGCAGTTAATAAATTATCTGTAAAACCCGATATACTTCTTAATG
ATGCAGTTACAATTCCAGGAATAGACATTAAACAGATTCCAATTATTAAAGGTGATGCCAAGAGTCTGTCAATTGCATCT
GCAAGTATTCTTGCGAAAGTAACAAGGGACAGACTTATGACCGAATATGATTCTTTGTATCCGGAATATGGATTTGCCAG
GCACAAAGGTTATGGAACTAAAGTTCATATTGAAGCAATAAAAGAGTACGGTCCATGTCCTATACACAGAAGAACATTTA
TTAAGAATTTTATATAG

Upstream 100 bases:

>100_bases
ATTATGAAAAATGTGCTGCATGTATTCTTGATGATTTCAGAGAAGGAAAGATTGGTACAATCTCACTTGAAAGACCTTAA
AGATACCGGAAAGGAAAGCT

Downstream 100 bases:

>100_bases
GTGAACGTATATGAATATTAATATGTCCGATTTTTTCAAAAATAATATATCATCAGGCAGCCAGACCACAGATGTTAATG
TGTCGGAAAATGTATCACAT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTLKEERELKKAAKLEAEKQRIEAMREYEEMYDTFSYICGIDEAGRGPLAGPVVAGAVILPKGKRILYVNDSKKLSEKKR
DELFDVIKEEALSYGIGIVSPERIDEINILQATYEAMHEAVNKLSVKPDILLNDAVTIPGIDIKQIPIIKGDAKSLSIAS
ASILAKVTRDRLMTEYDSLYPEYGFARHKGYGTKVHIEAIKEYGPCPIHRRTFIKNFI

Sequences:

>Translated_218_residues
MTLKEERELKKAAKLEAEKQRIEAMREYEEMYDTFSYICGIDEAGRGPLAGPVVAGAVILPKGKRILYVNDSKKLSEKKR
DELFDVIKEEALSYGIGIVSPERIDEINILQATYEAMHEAVNKLSVKPDILLNDAVTIPGIDIKQIPIIKGDAKSLSIAS
ASILAKVTRDRLMTEYDSLYPEYGFARHKGYGTKVHIEAIKEYGPCPIHRRTFIKNFI
>Mature_217_residues
TLKEERELKKAAKLEAEKQRIEAMREYEEMYDTFSYICGIDEAGRGPLAGPVVAGAVILPKGKRILYVNDSKKLSEKKRD
ELFDVIKEEALSYGIGIVSPERIDEINILQATYEAMHEAVNKLSVKPDILLNDAVTIPGIDIKQIPIIKGDAKSLSIASA
SILAKVTRDRLMTEYDSLYPEYGFARHKGYGTKVHIEAIKEYGPCPIHRRTFIKNFI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=47.5675675675676, Blast_Score=175, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17536263, Length=237, Percent_Identity=29.1139240506329, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 24561; Mature: 24430

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKEERELKKAAKLEAEKQRIEAMREYEEMYDTFSYICGIDEAGRGPLAGPVVAGAVIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCEEEE
PKGKRILYVNDSKKLSEKKRDELFDVIKEEALSYGIGIVSPERIDEINILQATYEAMHEA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHH
VNKLSVKPDILLNDAVTIPGIDIKQIPIIKGDAKSLSIASASILAKVTRDRLMTEYDSLY
HHHCCCCCCEEECCCEECCCCCCEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PEYGFARHKGYGTKVHIEAIKEYGPCPIHRRTFIKNFI
CCCCCHHHCCCCCEEEHEEHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TLKEERELKKAAKLEAEKQRIEAMREYEEMYDTFSYICGIDEAGRGPLAGPVVAGAVIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCEEEE
PKGKRILYVNDSKKLSEKKRDELFDVIKEEALSYGIGIVSPERIDEINILQATYEAMHEA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHH
VNKLSVKPDILLNDAVTIPGIDIKQIPIIKGDAKSLSIASASILAKVTRDRLMTEYDSLY
HHHCCCCCCEEECCCEECCCCCCEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PEYGFARHKGYGTKVHIEAIKEYGPCPIHRRTFIKNFI
CCCCCHHHCCCCCEEEHEEHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA