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The map label for this gene is yqgN [H]

Identifier: 238916917

GI number: 238916917

Start: 1001483

End: 1002043

Strand: Direct

Name: yqgN [H]

Synonym: EUBELI_00986

Alternate gene names: 238916917

Gene position: 1001483-1002043 (Clockwise)

Preceding gene: 238916916

Following gene: 238916918

Centisome position: 46.71

GC content: 35.29

Gene sequence:

>561_bases
ATGGATAAGAATGAAGTGCGTCAGCTTATTATGAACCGCAGACATGAATTGTCAGATGAAGATATTGAAATGCAGAGTGG
ACTTATAATTGACAGATTGAAAAAATCGGACATATATAAGACATCGGAAAATGTATTTCTGTATATGAGCTATAACAGGG
AAGTTGATACATATATGCTTCTTTCGCAGTGCTTTATGGATGGCAAGAAAGTATATGCTCCAAAAGTTTTATCAAAGACA
CAGATGGAGTTTTATTGCTTATCTGATGAGAATGATCTTGTAAGTGGTTATATGGGAATTATGGAACCGTCTGACGTCTG
CGATAAAGCTAAGATCAGAGATGGACTTTTTATTATGCCGGGACTTGCGTTTGATTATGATTTTCACAGAATAGGTTATG
GCGGAGGCTTTTATGACAGATATCTATCGGAAGATAATACATTTATAAAAGCGGCACTTGCTTTTGATTTCCAGCTTTTA
GAGAGTATTCCTTATGAGGAACATGATTTAAAACCGGATTATATTATTACACAGACACAGTTTATAAGGAGGGAGAATTG
A

Upstream 100 bases:

>100_bases
TAAGATTAAGAATCCTGATGGTTCTTTAATAGATGTCAAGGCAAGACATGATGAGAAGATGAAAAGATTGGCAGAGGAAC
AGGCAGAGAAAGGTAACTAG

Downstream 100 bases:

>100_bases
TGGAATCACTTGAACAGATTGGAATTAAGGCTAAGAAGGCATCAAGATATCTTGCTAAGCTTGGAATAGATGAGAAGAAT
AAGGCACTTGAAGCGGTTGC

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDKNEVRQLIMNRRHELSDEDIEMQSGLIIDRLKKSDIYKTSENVFLYMSYNREVDTYMLLSQCFMDGKKVYAPKVLSKT
QMEFYCLSDENDLVSGYMGIMEPSDVCDKAKIRDGLFIMPGLAFDYDFHRIGYGGGFYDRYLSEDNTFIKAALAFDFQLL
ESIPYEEHDLKPDYIITQTQFIRREN

Sequences:

>Translated_186_residues
MDKNEVRQLIMNRRHELSDEDIEMQSGLIIDRLKKSDIYKTSENVFLYMSYNREVDTYMLLSQCFMDGKKVYAPKVLSKT
QMEFYCLSDENDLVSGYMGIMEPSDVCDKAKIRDGLFIMPGLAFDYDFHRIGYGGGFYDRYLSEDNTFIKAALAFDFQLL
ESIPYEEHDLKPDYIITQTQFIRREN
>Mature_186_residues
MDKNEVRQLIMNRRHELSDEDIEMQSGLIIDRLKKSDIYKTSENVFLYMSYNREVDTYMLLSQCFMDGKKVYAPKVLSKT
QMEFYCLSDENDLVSGYMGIMEPSDVCDKAKIRDGLFIMPGLAFDYDFHRIGYGGGFYDRYLSEDNTFIKAALAFDFQLL
ESIPYEEHDLKPDYIITQTQFIRREN

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=178, Percent_Identity=30.3370786516854, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17510857, Length=194, Percent_Identity=25.7731958762887, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21917; Mature: 21917

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00052 RIBOSOMAL_S7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNEVRQLIMNRRHELSDEDIEMQSGLIIDRLKKSDIYKTSENVFLYMSYNREVDTYML
CCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHH
LSQCFMDGKKVYAPKVLSKTQMEFYCLSDENDLVSGYMGIMEPSDVCDKAKIRDGLFIMP
HHHHHHCCCEEECCHHHCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCEEECC
GLAFDYDFHRIGYGGGFYDRYLSEDNTFIKAALAFDFQLLESIPYEEHDLKPDYIITQTQ
CCEECCCCEEECCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEHHH
FIRREN
HHCCCC
>Mature Secondary Structure
MDKNEVRQLIMNRRHELSDEDIEMQSGLIIDRLKKSDIYKTSENVFLYMSYNREVDTYML
CCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCCEECCCCEEEEEEECCCHHHHHH
LSQCFMDGKKVYAPKVLSKTQMEFYCLSDENDLVSGYMGIMEPSDVCDKAKIRDGLFIMP
HHHHHHCCCEEECCHHHCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCEEECC
GLAFDYDFHRIGYGGGFYDRYLSEDNTFIKAALAFDFQLLESIPYEEHDLKPDYIITQTQ
CCEECCCCEEECCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEHHH
FIRREN
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]