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The map label for this gene is ruvB [H]

Identifier: 238916874

GI number: 238916874

Start: 959141

End: 960154

Strand: Direct

Name: ruvB [H]

Synonym: EUBELI_00943

Alternate gene names: 238916874

Gene position: 959141-960154 (Clockwise)

Preceding gene: 238916873

Following gene: 238916875

Centisome position: 44.73

GC content: 40.43

Gene sequence:

>1014_bases
ATGAGGGGCTATATGGAAAAGAGGATTATATCAACACAGATAACTGAAGAAGATTATGGTATTGAGAATTCCTTAAGACC
ATTATCTCTCGATGACTATGTTGGACAGAATAAGGTTAAGAGTAATCTTAAAGTATATATTGAGGCAGCAAAGGAAAGAG
GAGAGGCACTTGACCATGTACTTTTCTATGGACCTCCGGGACTTGGAAAGACAACTCTGGCAGGAATTATTGCTAATGAA
ATGGGGGTTAATATCAAGGTTACATCCGGTCCTGCAATCGAGAAGCCGGGAGATATGGCAGCTATACTTAACAACTTAAG
TGAGGGTGATATTCTATTTGTTGATGAGATTCACAGACTTAACAGACAGGTAGAAGAAGTGCTGTATCCTGCAATGGAGG
ACTATAAGATTGATATTATGATCGGAAAGGGTGCAACAGCAAGGTCTATAAGACTTGAACTGCCACAGTTCACTCTGATA
GGGGCAACAACAAGAGCGGGACTTTTATCAGCACCCTTAAGAGACAGATTCGGTGTTGTAAGCCATATGGAATTCTATAC
AGTTCCGGAGCTTGAGAAAATCATTATCCGTTCAGCCAATGTGCTTAATGTTGATATTGACTCAGACGGAGCACATGAGC
TTGCAAGAAGGTCAAGGGGAACACCGAGACTTGCCAACAGACTTTTAAAGAGAGTGCGAGATTTTGCACAGGTTAAATAT
AACGGACATATCAATAAGGATGTTGCTGATTATGCACTTAATCTGTTAGATGTTGACAGAGATGGATTGGACCGTAACGA
TCGTGTTATACTTACTACAATAGTTGATAAGTTTGATGGCGGACCTGTCGGTATTGAGACACTGGCAGCTTCAATAGGCG
AGGATTCAGGAACTCTTGAAGATGTTTATGAGCCATATCTTATACAGAACGGGTATATTAACAGAACTCCAAGAGGAAGA
GTTGCAACTAAAGCAGCTTATGATAATCTTGGCAGGCCATTTAAACAAAAATAA

Upstream 100 bases:

>100_bases
TCAAGGAAGTGGAAGATATAGAGAATAAGGATTCTGAGACGGTTCTTAAGGAAGCGTTAAAGAAGCTGGTTAAATTCTAG
AACAGAATAGTATTTAAGAA

Downstream 100 bases:

>100_bases
CATAAAATATTCTAAAGAATGCGTTTTATGAGTTGAATAGTAAGTGTATTTATTATATACTTAATATGTTTATTTCTACA
TATATGGAGGGGACTTATGT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRGYMEKRIISTQITEEDYGIENSLRPLSLDDYVGQNKVKSNLKVYIEAAKERGEALDHVLFYGPPGLGKTTLAGIIANE
MGVNIKVTSGPAIEKPGDMAAILNNLSEGDILFVDEIHRLNRQVEEVLYPAMEDYKIDIMIGKGATARSIRLELPQFTLI
GATTRAGLLSAPLRDRFGVVSHMEFYTVPELEKIIIRSANVLNVDIDSDGAHELARRSRGTPRLANRLLKRVRDFAQVKY
NGHINKDVADYALNLLDVDRDGLDRNDRVILTTIVDKFDGGPVGIETLAASIGEDSGTLEDVYEPYLIQNGYINRTPRGR
VATKAAYDNLGRPFKQK

Sequences:

>Translated_337_residues
MRGYMEKRIISTQITEEDYGIENSLRPLSLDDYVGQNKVKSNLKVYIEAAKERGEALDHVLFYGPPGLGKTTLAGIIANE
MGVNIKVTSGPAIEKPGDMAAILNNLSEGDILFVDEIHRLNRQVEEVLYPAMEDYKIDIMIGKGATARSIRLELPQFTLI
GATTRAGLLSAPLRDRFGVVSHMEFYTVPELEKIIIRSANVLNVDIDSDGAHELARRSRGTPRLANRLLKRVRDFAQVKY
NGHINKDVADYALNLLDVDRDGLDRNDRVILTTIVDKFDGGPVGIETLAASIGEDSGTLEDVYEPYLIQNGYINRTPRGR
VATKAAYDNLGRPFKQK
>Mature_337_residues
MRGYMEKRIISTQITEEDYGIENSLRPLSLDDYVGQNKVKSNLKVYIEAAKERGEALDHVLFYGPPGLGKTTLAGIIANE
MGVNIKVTSGPAIEKPGDMAAILNNLSEGDILFVDEIHRLNRQVEEVLYPAMEDYKIDIMIGKGATARSIRLELPQFTLI
GATTRAGLLSAPLRDRFGVVSHMEFYTVPELEKIIIRSANVLNVDIDSDGAHELARRSRGTPRLANRLLKRVRDFAQVKY
NGHINKDVADYALNLLDVDRDGLDRNDRVILTTIVDKFDGGPVGIETLAASIGEDSGTLEDVYEPYLIQNGYINRTPRGR
VATKAAYDNLGRPFKQK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=324, Percent_Identity=59.5679012345679, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1787119, Length=135, Percent_Identity=35.5555555555556, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37461; Mature: 37461

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGYMEKRIISTQITEEDYGIENSLRPLSLDDYVGQNKVKSNLKVYIEAAKERGEALDHV
CCCHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHCCHHHHHCCHHEEEHHHHHHHHHHCEE
LFYGPPGLGKTTLAGIIANEMGVNIKVTSGPAIEKPGDMAAILNNLSEGDILFVDEIHRL
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHH
NRQVEEVLYPAMEDYKIDIMIGKGATARSIRLELPQFTLIGATTRAGLLSAPLRDRFGVV
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHCCCHHHHHCHH
SHMEFYTVPELEKIIIRSANVLNVDIDSDGAHELARRSRGTPRLANRLLKRVRDFAQVKY
HHHHEECCCHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEE
NGHINKDVADYALNLLDVDRDGLDRNDRVILTTIVDKFDGGPVGIETLAASIGEDSGTLE
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCCCCCHH
DVYEPYLIQNGYINRTPRGRVATKAAYDNLGRPFKQK
HHHCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGYMEKRIISTQITEEDYGIENSLRPLSLDDYVGQNKVKSNLKVYIEAAKERGEALDHV
CCCHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHCCHHHHHCCHHEEEHHHHHHHHHHCEE
LFYGPPGLGKTTLAGIIANEMGVNIKVTSGPAIEKPGDMAAILNNLSEGDILFVDEIHRL
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHH
NRQVEEVLYPAMEDYKIDIMIGKGATARSIRLELPQFTLIGATTRAGLLSAPLRDRFGVV
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHCCCHHHHHCHH
SHMEFYTVPELEKIIIRSANVLNVDIDSDGAHELARRSRGTPRLANRLLKRVRDFAQVKY
HHHHEECCCHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEE
NGHINKDVADYALNLLDVDRDGLDRNDRVILTTIVDKFDGGPVGIETLAASIGEDSGTLE
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCCCCCHH
DVYEPYLIQNGYINRTPRGRVATKAAYDNLGRPFKQK
HHHCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA