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The map label for this gene is ruvA

Identifier: 238916873

GI number: 238916873

Start: 958497

End: 959120

Strand: Direct

Name: ruvA

Synonym: EUBELI_00942

Alternate gene names: 238916873

Gene position: 958497-959120 (Clockwise)

Preceding gene: 238916872

Following gene: 238916874

Centisome position: 44.7

GC content: 38.3

Gene sequence:

>624_bases
ATGATTTCATACATTAAAGGTGAGCTGGCCGAAATCCTGCCAGATGTAATCGTTGTGGAAGCCAATGGAATCGGATATAA
TATATATGTTCCGGGTTCAGTTCCTGGTGAGCTTCCATCAGTTGGCAGTGAGGTTAAGATATATACATATATGAATGTCA
AGGAAGATGAATGCAGTCTGTTCGGATTCCTTACAAGAGATGATTTAAGCATGTTTAAAATGCTTATCTGCGTCAATGGT
ATTGGCCCTAAGGCAGCGCTTGGTGCATTATCTAATATCACAGCAGATGATTTAAGATTTGCAGTTCTTGCTGATGATGT
GGCAGCAATCAAGGCACTTCCTGGTATCGGACCTAAAACAGCACAGAAGATTATAATTGAGCTTAAAGATAAGTTAAAGC
TTGATGAAGTATTTGAATCAGCACTTTCTAAGAATAAAAAGGCAGACAATAACAGTAATGTAAGTAATGTCATGATGATA
AGAAATGACGCTGTTGAGGCACTTGTATCACTTGGATATTCAAGCAAAGATGCACTTGTTGCTGTCAAGGAAGTGGAAGA
TATAGAGAATAAGGATTCTGAGACGGTTCTTAAGGAAGCGTTAAAGAAGCTGGTTAAATTCTAG

Upstream 100 bases:

>100_bases
AAGAGCTTATGGCAGAGGCTAACAAGTGGGAACTTTCACATGGTGGAATATCAGGAAGAACAGCACAGCAGTTTATCAAT
TACTGTCTTGGGGGTAGAGA

Downstream 100 bases:

>100_bases
AACAGAATAGTATTTAAGAAATGAGGGGCTATATGGAAAAGAGGATTATATCAACACAGATAACTGAAGAAGATTATGGT
ATTGAGAATTCCTTAAGACC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MISYIKGELAEILPDVIVVEANGIGYNIYVPGSVPGELPSVGSEVKIYTYMNVKEDECSLFGFLTRDDLSMFKMLICVNG
IGPKAALGALSNITADDLRFAVLADDVAAIKALPGIGPKTAQKIIIELKDKLKLDEVFESALSKNKKADNNSNVSNVMMI
RNDAVEALVSLGYSSKDALVAVKEVEDIENKDSETVLKEALKKLVKF

Sequences:

>Translated_207_residues
MISYIKGELAEILPDVIVVEANGIGYNIYVPGSVPGELPSVGSEVKIYTYMNVKEDECSLFGFLTRDDLSMFKMLICVNG
IGPKAALGALSNITADDLRFAVLADDVAAIKALPGIGPKTAQKIIIELKDKLKLDEVFESALSKNKKADNNSNVSNVMMI
RNDAVEALVSLGYSSKDALVAVKEVEDIENKDSETVLKEALKKLVKF
>Mature_207_residues
MISYIKGELAEILPDVIVVEANGIGYNIYVPGSVPGELPSVGSEVKIYTYMNVKEDECSLFGFLTRDDLSMFKMLICVNG
IGPKAALGALSNITADDLRFAVLADDVAAIKALPGIGPKTAQKIIIELKDKLKLDEVFESALSKNKKADNNSNVSNVMMI
RNDAVEALVSLGYSSKDALVAVKEVEDIENKDSETVLKEALKKLVKF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=209, Percent_Identity=34.9282296650718, Blast_Score=126, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_EUBE2 (C4Z030)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930390.1
- GeneID:   7957803
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_00942
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF00633 HHH; PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22402; Mature: 22402

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISYIKGELAEILPDVIVVEANGIGYNIYVPGSVPGELPSVGSEVKIYTYMNVKEDECSL
CCCCHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHE
FGFLTRDDLSMFKMLICVNGIGPKAALGALSNITADDLRFAVLADDVAAIKALPGIGPKT
EEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHCCCCCHHH
AQKIIIELKDKLKLDEVFESALSKNKKADNNSNVSNVMMIRNDAVEALVSLGYSSKDALV
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEE
AVKEVEDIENKDSETVLKEALKKLVKF
EHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISYIKGELAEILPDVIVVEANGIGYNIYVPGSVPGELPSVGSEVKIYTYMNVKEDECSL
CCCCHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHE
FGFLTRDDLSMFKMLICVNGIGPKAALGALSNITADDLRFAVLADDVAAIKALPGIGPKT
EEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHCCCCCHHH
AQKIIIELKDKLKLDEVFESALSKNKKADNNSNVSNVMMIRNDAVEALVSLGYSSKDALV
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEE
AVKEVEDIENKDSETVLKEALKKLVKF
EHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA