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The map label for this gene is bceR [H]

Identifier: 238916798

GI number: 238916798

Start: 880259

End: 881047

Strand: Direct

Name: bceR [H]

Synonym: EUBELI_00865

Alternate gene names: 238916798

Gene position: 880259-881047 (Clockwise)

Preceding gene: 238916797

Following gene: 238916799

Centisome position: 41.05

GC content: 37.14

Gene sequence:

>789_bases
ATGCGGACTCGAAACCAGCTTATATTTATAAAAAGACAGAGAAACCTTTTTGCGTTTTCTCTGTCTTTTTTTAGTAAAAC
AGTTTACAATACATTTATATCAAAATGTAGTGAGGAACTGATAATGAACAGAATTCTGATTGTTGAAGACGATAAAGATA
TAAGCAGGGAGCTTAAGGAACTGCTGGAAAATTCAGGGTATGAGGCAGAGGTTCTGTCTAATTTTAAAAATGCATGTGAC
AGTATTATTGCTGAAGAGCCGGATCTTGTTCTGCTTGATATCAATATTCCGTATATGAATGGGGAAATGCTTTTGCAGCA
GTTAAGGAGTAAATCAGATGTGCCGGTTATTATGGTTACAAGCAGGGATTCAGAGGCTGACGAGGTGCTTTCCATGAGTT
ATGGGGCAGACGATTATATAACAAAGCCGTATAATCCGACAATACTTCTGTTAAGGATTAATGCGGTATTTAAGCGGCTT
GGTGCGAAGTCAGATAATACAACAACTTACCGTGGAATGGAAATACTGCCACACAAGGGTGTAATTAAGTATAAGGATGA
CGAGATAACTCTTACTAAAAATGAAATGACAATATTCATGTATCTGTTATCACACAGGGAGCATATAGTTTCAAGAGATG
AGCTTATGACTGAGCTGTGGAACAATGAGGAGTACCTTAATGACAATGCGCTTACTGTGAATATAAGCAGGTTAAGAGGC
AGATTTAAAGATATTGGACTTGAAGATGTTATTGAGACAAGAAAGGGACAGGGATATATTCTTGTATGA

Upstream 100 bases:

>100_bases
CCACGAGAATCAAGTTCTGGCGGTTCGTCAGGCGGTGGCGGCGGAGGCGGCTCATCCGGCGGTGGTGGAGGAAGTGGCGG
CGGCCACAGCTTCTAACAGG

Downstream 100 bases:

>100_bases
GGTTAGGAAAATATATTAAAGACAGACTGTATTCAGTGTGCATATTTGTGGCAATGCTTATCATAAGCGTACTTATGATG
GCGGCATTCAAGGTGTCTGT

Product: two-component system OmpR family response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MRTRNQLIFIKRQRNLFAFSLSFFSKTVYNTFISKCSEELIMNRILIVEDDKDISRELKELLENSGYEAEVLSNFKNACD
SIIAEEPDLVLLDINIPYMNGEMLLQQLRSKSDVPVIMVTSRDSEADEVLSMSYGADDYITKPYNPTILLLRINAVFKRL
GAKSDNTTTYRGMEILPHKGVIKYKDDEITLTKNEMTIFMYLLSHREHIVSRDELMTELWNNEEYLNDNALTVNISRLRG
RFKDIGLEDVIETRKGQGYILV

Sequences:

>Translated_262_residues
MRTRNQLIFIKRQRNLFAFSLSFFSKTVYNTFISKCSEELIMNRILIVEDDKDISRELKELLENSGYEAEVLSNFKNACD
SIIAEEPDLVLLDINIPYMNGEMLLQQLRSKSDVPVIMVTSRDSEADEVLSMSYGADDYITKPYNPTILLLRINAVFKRL
GAKSDNTTTYRGMEILPHKGVIKYKDDEITLTKNEMTIFMYLLSHREHIVSRDELMTELWNNEEYLNDNALTVNISRLRG
RFKDIGLEDVIETRKGQGYILV
>Mature_262_residues
MRTRNQLIFIKRQRNLFAFSLSFFSKTVYNTFISKCSEELIMNRILIVEDDKDISRELKELLENSGYEAEVLSNFKNACD
SIIAEEPDLVLLDINIPYMNGEMLLQQLRSKSDVPVIMVTSRDSEADEVLSMSYGADDYITKPYNPTILLLRINAVFKRL
GAKSDNTTTYRGMEILPHKGVIKYKDDEITLTKNEMTIFMYLLSHREHIVSRDELMTELWNNEEYLNDNALTVNISRLRG
RFKDIGLEDVIETRKGQGYILV

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=30.0448430493274, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=30.1369863013699, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=28.0542986425339, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.4561403508772, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=28.310502283105, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=33.9130434782609, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=30.2222222222222, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=219, Percent_Identity=27.3972602739726, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=27.3972602739726, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=27.9279279279279, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=28.125, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=30.2127659574468, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=28.3842794759825, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=28.1818181818182, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30418; Mature: 30418

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRNQLIFIKRQRNLFAFSLSFFSKTVYNTFISKCSEELIMNRILIVEDDKDISRELKE
CCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHH
LLENSGYEAEVLSNFKNACDSIIAEEPDLVLLDINIPYMNGEMLLQQLRSKSDVPVIMVT
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEE
SRDSEADEVLSMSYGADDYITKPYNPTILLLRINAVFKRLGAKSDNTTTYRGMEILPHKG
CCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEECCEEECCCCC
VIKYKDDEITLTKNEMTIFMYLLSHREHIVSRDELMTELWNNEEYLNDNALTVNISRLRG
EEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH
RFKDIGLEDVIETRKGQGYILV
HHHCCCHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MRTRNQLIFIKRQRNLFAFSLSFFSKTVYNTFISKCSEELIMNRILIVEDDKDISRELKE
CCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHH
LLENSGYEAEVLSNFKNACDSIIAEEPDLVLLDINIPYMNGEMLLQQLRSKSDVPVIMVT
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEE
SRDSEADEVLSMSYGADDYITKPYNPTILLLRINAVFKRLGAKSDNTTTYRGMEILPHKG
CCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEECCEEECCCCC
VIKYKDDEITLTKNEMTIFMYLLSHREHIVSRDELMTELWNNEEYLNDNALTVNISRLRG
EEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH
RFKDIGLEDVIETRKGQGYILV
HHHCCCHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 14612242; 12890034 [H]