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The map label for this gene is flhF [H]

Identifier: 238916769

GI number: 238916769

Start: 845149

End: 846447

Strand: Direct

Name: flhF [H]

Synonym: EUBELI_00831

Alternate gene names: 238916769

Gene position: 845149-846447 (Clockwise)

Preceding gene: 238916768

Following gene: 238916770

Centisome position: 39.42

GC content: 32.79

Gene sequence:

>1299_bases
ATGATAGTTAAAAAATTTCAGGCAGATACAGAGACGGAAGCTATATTAAAAGCGAAGGAAGAGTTAGGCAATGGTGCAGT
AGTTCTTAATGTTAAAACATTGAAACAGAGGGGAATATTCCGATTGTTTAAGAAGGATGTTGTTGAAGTTACGGCTGCAT
TAGAAGAAAAAGATTTTATCAATGGGATTAATAATAAAAAACCAACATTTGATAATAAGAAGGCAGCTAATAGTGGATTT
AATACAGGAATTGGCAATATGAAGAGTATTACAGAGTCAAAGCCTGTTATAAATTTAGTGGCTGATGAAAAAATAGATGT
TAATGGCAATGCTGCAAATATTGAAAAGAAACTTGATTCATTACATTCTCTTTTAGAAAATCAGATTACCTCATCATCAG
CTGTACATAAAAAACAGGATACATATGTGCAGAATACGAATTTGAATGATAAAGATGTAACACCGGGTAAACAGATAGTA
AAGGAACGTGAAAATGCAAATTATAAATTTTTGCAGCTGATATATAAGAAGATGATAGGGAATGAAGTTGATACCAAATA
CGCTGATGAAATTATAAGCGATATAGAAGCTTCATTAAAAAAGGAATCTAATATTGACAGTATTCTTGCAGCTGTTTATC
AGAAAATCATACTTAAGCTGGGTACACCTAAAACTATTTCGTTAGGAGATAAGCCAAAGGTTATACTTTTTATCGGACCT
ACAGGGGTTGGTAAAACTACAACTATTGCTAAAATAGCGTCTCATTTTAAGCTTGAAAAAGAAACTAAAGTTGCATTTAT
AACATCAGATACATATAGAATTGCTGCAGTTGATCAGCTTAATACATATGCTTCGATTATAGATTGTCCGGTTAATGTGG
CTTATTCTGCGGATGAAATAGGTGAATGCCTTGATGAGTTTAAGGATTATGAACTTATACTTGTAGATACAGCCGGAAGA
TCGCATAAATCTGAGGAGCAGATGGAAGAATTAGACAATCTGATTGAAATGATTGCTTCGAGAGCAGATGAATTTGATCT
TGAAATATATCTTACATTAAGTGTGACAACTAAGTATAAAGATTTAGTAAATATTGCGGATAAGTACAGACATATTGAAA
ACTGGGCACTCATATTTACTAAACTGGATGAAACCTGTTACCTTGGTAACATGCTTAATATGAAGCTGTATACAGGAGCA
CCACTTTCTTATACAACATCGGGACAGAATGTACCTAATGATATAGAGGTTATAAATGAACAAAGACTTGCTAAGTTATT
ATTGGGAGGTAATTCGTAA

Upstream 100 bases:

>100_bases
AAATCTTGCAAAGGACTATTATAAAGACATTATTGTGATTTCATATAATGAAGTTGAATCAAATGTTGAATTACAATCAG
TTGGGATGGTGACAGCGTAA

Downstream 100 bases:

>100_bases
TGGATCAGGCAGAAAATCTCCGTAATATAATAAAAAAACAAAACCAGCGGGATGTCGGTAATGCGCGTGTTATTGCTGTA
ACCAGTGGAAAAGGTGGTGT

Product: flagellar biosynthesis protein FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIVKKFQADTETEAILKAKEELGNGAVVLNVKTLKQRGIFRLFKKDVVEVTAALEEKDFINGINNKKPTFDNKKAANSGF
NTGIGNMKSITESKPVINLVADEKIDVNGNAANIEKKLDSLHSLLENQITSSSAVHKKQDTYVQNTNLNDKDVTPGKQIV
KERENANYKFLQLIYKKMIGNEVDTKYADEIISDIEASLKKESNIDSILAAVYQKIILKLGTPKTISLGDKPKVILFIGP
TGVGKTTTIAKIASHFKLEKETKVAFITSDTYRIAAVDQLNTYASIIDCPVNVAYSADEIGECLDEFKDYELILVDTAGR
SHKSEEQMEELDNLIEMIASRADEFDLEIYLTLSVTTKYKDLVNIADKYRHIENWALIFTKLDETCYLGNMLNMKLYTGA
PLSYTTSGQNVPNDIEVINEQRLAKLLLGGNS

Sequences:

>Translated_432_residues
MIVKKFQADTETEAILKAKEELGNGAVVLNVKTLKQRGIFRLFKKDVVEVTAALEEKDFINGINNKKPTFDNKKAANSGF
NTGIGNMKSITESKPVINLVADEKIDVNGNAANIEKKLDSLHSLLENQITSSSAVHKKQDTYVQNTNLNDKDVTPGKQIV
KERENANYKFLQLIYKKMIGNEVDTKYADEIISDIEASLKKESNIDSILAAVYQKIILKLGTPKTISLGDKPKVILFIGP
TGVGKTTTIAKIASHFKLEKETKVAFITSDTYRIAAVDQLNTYASIIDCPVNVAYSADEIGECLDEFKDYELILVDTAGR
SHKSEEQMEELDNLIEMIASRADEFDLEIYLTLSVTTKYKDLVNIADKYRHIENWALIFTKLDETCYLGNMLNMKLYTGA
PLSYTTSGQNVPNDIEVINEQRLAKLLLGGNS
>Mature_432_residues
MIVKKFQADTETEAILKAKEELGNGAVVLNVKTLKQRGIFRLFKKDVVEVTAALEEKDFINGINNKKPTFDNKKAANSGF
NTGIGNMKSITESKPVINLVADEKIDVNGNAANIEKKLDSLHSLLENQITSSSAVHKKQDTYVQNTNLNDKDVTPGKQIV
KERENANYKFLQLIYKKMIGNEVDTKYADEIISDIEASLKKESNIDSILAAVYQKIILKLGTPKTISLGDKPKVILFIGP
TGVGKTTTIAKIASHFKLEKETKVAFITSDTYRIAAVDQLNTYASIIDCPVNVAYSADEIGECLDEFKDYELILVDTAGR
SHKSEEQMEELDNLIEMIASRADEFDLEIYLTLSVTTKYKDLVNIADKYRHIENWALIFTKLDETCYLGNMLNMKLYTGA
PLSYTTSGQNVPNDIEVINEQRLAKLLLGGNS

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=215, Percent_Identity=29.7674418604651, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4507215, Length=215, Percent_Identity=29.7674418604651, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789874, Length=203, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788963, Length=205, Percent_Identity=28.780487804878, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539958, Length=214, Percent_Identity=27.1028037383178, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206261, Length=204, Percent_Identity=31.3725490196078, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=205, Percent_Identity=26.3414634146341, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647949, Length=239, Percent_Identity=28.8702928870293, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 48140; Mature: 48140

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKKFQADTETEAILKAKEELGNGAVVLNVKTLKQRGIFRLFKKDVVEVTAALEEKDFI
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGINNKKPTFDNKKAANSGFNTGIGNMKSITESKPVINLVADEKIDVNGNAANIEKKLDS
CCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHH
LHSLLENQITSSSAVHKKQDTYVQNTNLNDKDVTPGKQIVKERENANYKFLQLIYKKMIG
HHHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
NEVDTKYADEIISDIEASLKKESNIDSILAAVYQKIILKLGTPKTISLGDKPKVILFIGP
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECC
TGVGKTTTIAKIASHFKLEKETKVAFITSDTYRIAAVDQLNTYASIIDCPVNVAYSADEI
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCEEECHHHH
GECLDEFKDYELILVDTAGRSHKSEEQMEELDNLIEMIASRADEFDLEIYLTLSVTTKYK
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHH
DLVNIADKYRHIENWALIFTKLDETCYLGNMLNMKLYTGAPLSYTTSGQNVPNDIEVINE
HHHHHHHHHHHHHCCEEEEEECCCCEEECCEEEEEEEECCCCEEECCCCCCCHHHHHHHH
QRLAKLLLGGNS
HHHHHHHCCCCC
>Mature Secondary Structure
MIVKKFQADTETEAILKAKEELGNGAVVLNVKTLKQRGIFRLFKKDVVEVTAALEEKDFI
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGINNKKPTFDNKKAANSGFNTGIGNMKSITESKPVINLVADEKIDVNGNAANIEKKLDS
CCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHH
LHSLLENQITSSSAVHKKQDTYVQNTNLNDKDVTPGKQIVKERENANYKFLQLIYKKMIG
HHHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
NEVDTKYADEIISDIEASLKKESNIDSILAAVYQKIILKLGTPKTISLGDKPKVILFIGP
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECC
TGVGKTTTIAKIASHFKLEKETKVAFITSDTYRIAAVDQLNTYASIIDCPVNVAYSADEI
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCCCCEEECHHHH
GECLDEFKDYELILVDTAGRSHKSEEQMEELDNLIEMIASRADEFDLEIYLTLSVTTKYK
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHH
DLVNIADKYRHIENWALIFTKLDETCYLGNMLNMKLYTGAPLSYTTSGQNVPNDIEVINE
HHHHHHHHHHHHHCCEEEEEECCCCEEECCEEEEEEEECCCCEEECCCCCCCHHHHHHHH
QRLAKLLLGGNS
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447978; 9384377 [H]