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The map label for this gene is serC [H]

Identifier: 238916702

GI number: 238916702

Start: 775316

End: 776416

Strand: Direct

Name: serC [H]

Synonym: EUBELI_00764

Alternate gene names: 238916702

Gene position: 775316-776416 (Clockwise)

Preceding gene: 238916701

Following gene: 238916703

Centisome position: 36.16

GC content: 40.05

Gene sequence:

>1101_bases
GTGAGTAGAGTTTATAACTTTAGCGCTGGTCCAGCTGTTTTACCAGAGGAAGTACTCAAAGAAGCAGCAGATGAAATGTT
AGATTACCAGGGAAGCGGTCAGTCGGTAATGGAAATGAGCCACAGATCCAAGGTTTATGACAACATCATCAAAGAGGCAG
AGAAGGATTTAAGAGACCTTCTTAACATCCCAGATAACTATAAGGTGTTATTTTTACAGGGTGGTGCATCGCAGTTCTTC
GCTGAAGTGCCTATGAACCTTATGAAGAATAAGAAAGCAGGTTATATCCTTACAGGACAGTGGGCTAAGAAAGCATTTGC
AGAAGCTAAGATATATGGAGAGGCTGTTGAGCTTGCTTCATCAGCAGACAAGACATTTTCATATATTCCAGACTGCTCAG
ATCTTGATATTCCAGAGGATCTTGACTATGTATATATCTGTGAGAACAACACAATTTACGGAACAAAGTATAAGACATTA
CCTAACACTAAGGGTCATATTCTTGTATCAGATGTTTCATCATGCTTCTTATCAGAACCTATGGATGTAACTAAGTACGG
CGTTGTATACGGCGGTGTTCAGAAGAACATCGGACCAGCAGGCGTTGTAATTGCTATTATCAGAGAAGATCTTATAACAG
ATGACGTTCTTCCAGGAACTCCTACAATGCTTAAGTGGAAGACACAGGCAGATGCAGATTCTCTTTATAATACACCACCA
TGCTACAATATCTATATCTGTGGCAAGGTGTTCAAGTGGATTAAGAAGATGGGTGGACTTTCAGCAATGAAGGAACACAA
TGAGAAGAAGGCTAAGATTCTTTATGATTTCCTTGATGAGAGCAAGTTATTCATGGGAACAGTTGTTAAGGAAGACCGTT
CACTTATGAATGTACCTTTTGTATGCAACATTGAAGATAAAGAAGCTAAGGATGCTATGGAAGCTAAGTTCATTAAGGAA
GCTGCAGCTGCAGGATTTGTTAACCTTAAGGGACACAGAACAGTTGGCGGTATGAGAGCATCTATCTACAATGCTATGCC
AATCGAAGGTGTAGAGAAGCTTGTTGAATTCATGAAGAAGTTCGAGAAGGAGAATGCATAA

Upstream 100 bases:

>100_bases
AGAGAAGACCTTAATAACAAGAAATAATTCATATATTGACTTTAATGTGATAAAGGACTAAAATAGTTCTTAATATTTTA
TATTTTAGGAGGAAGAAAAG

Downstream 100 bases:

>100_bases
TGATTAATGTTAATTGTCTTAATAATATAGCAGCCTGCGGATTAAAGCTTTTTTCTGATGAGTATAATACAGAAAGCTCA
TTTGAAGACGCACAGGCTGT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSRVYNFSAGPAVLPEEVLKEAADEMLDYQGSGQSVMEMSHRSKVYDNIIKEAEKDLRDLLNIPDNYKVLFLQGGASQFF
AEVPMNLMKNKKAGYILTGQWAKKAFAEAKIYGEAVELASSADKTFSYIPDCSDLDIPEDLDYVYICENNTIYGTKYKTL
PNTKGHILVSDVSSCFLSEPMDVTKYGVVYGGVQKNIGPAGVVIAIIREDLITDDVLPGTPTMLKWKTQADADSLYNTPP
CYNIYICGKVFKWIKKMGGLSAMKEHNEKKAKILYDFLDESKLFMGTVVKEDRSLMNVPFVCNIEDKEAKDAMEAKFIKE
AAAAGFVNLKGHRTVGGMRASIYNAMPIEGVEKLVEFMKKFEKENA

Sequences:

>Translated_366_residues
MSRVYNFSAGPAVLPEEVLKEAADEMLDYQGSGQSVMEMSHRSKVYDNIIKEAEKDLRDLLNIPDNYKVLFLQGGASQFF
AEVPMNLMKNKKAGYILTGQWAKKAFAEAKIYGEAVELASSADKTFSYIPDCSDLDIPEDLDYVYICENNTIYGTKYKTL
PNTKGHILVSDVSSCFLSEPMDVTKYGVVYGGVQKNIGPAGVVIAIIREDLITDDVLPGTPTMLKWKTQADADSLYNTPP
CYNIYICGKVFKWIKKMGGLSAMKEHNEKKAKILYDFLDESKLFMGTVVKEDRSLMNVPFVCNIEDKEAKDAMEAKFIKE
AAAAGFVNLKGHRTVGGMRASIYNAMPIEGVEKLVEFMKKFEKENA
>Mature_365_residues
SRVYNFSAGPAVLPEEVLKEAADEMLDYQGSGQSVMEMSHRSKVYDNIIKEAEKDLRDLLNIPDNYKVLFLQGGASQFFA
EVPMNLMKNKKAGYILTGQWAKKAFAEAKIYGEAVELASSADKTFSYIPDCSDLDIPEDLDYVYICENNTIYGTKYKTLP
NTKGHILVSDVSSCFLSEPMDVTKYGVVYGGVQKNIGPAGVVIAIIREDLITDDVLPGTPTMLKWKTQADADSLYNTPPC
YNIYICGKVFKWIKKMGGLSAMKEHNEKKAKILYDFLDESKLFMGTVVKEDRSLMNVPFVCNIEDKEAKDAMEAKFIKEA
AAAGFVNLKGHRTVGGMRASIYNAMPIEGVEKLVEFMKKFEKENA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=363, Percent_Identity=45.4545454545455, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI10863955, Length=320, Percent_Identity=43.4375, Blast_Score=270, Evalue=1e-72,
Organism=Escherichia coli, GI1787136, Length=370, Percent_Identity=44.5945945945946, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=42.3076923076923, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6324758, Length=392, Percent_Identity=39.2857142857143, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21356589, Length=365, Percent_Identity=44.3835616438356, Blast_Score=306, Evalue=1e-83,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40858; Mature: 40727

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVYNFSAGPAVLPEEVLKEAADEMLDYQGSGQSVMEMSHRSKVYDNIIKEAEKDLRDL
CCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIPDNYKVLFLQGGASQFFAEVPMNLMKNKKAGYILTGQWAKKAFAEAKIYGEAVELAS
HCCCCCCEEEEEECCHHHHHHHHCHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
SADKTFSYIPDCSDLDIPEDLDYVYICENNTIYGTKYKTLPNTKGHILVSDVSSCFLSEP
CCCCHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCCCCCEEEEHHHHHHHCCC
MDVTKYGVVYGGVQKNIGPAGVVIAIIREDLITDDVLPGTPTMLKWKTQADADSLYNTPP
CCHHHHHEEECCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHCCCCC
CYNIYICGKVFKWIKKMGGLSAMKEHNEKKAKILYDFLDESKLFMGTVVKEDRSLMNVPF
CEEEEEHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCE
VCNIEDKEAKDAMEAKFIKEAAAAGFVNLKGHRTVGGMRASIYNAMPIEGVEKLVEFMKK
EEECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
FEKENA
HHHCCC
>Mature Secondary Structure 
SRVYNFSAGPAVLPEEVLKEAADEMLDYQGSGQSVMEMSHRSKVYDNIIKEAEKDLRDL
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIPDNYKVLFLQGGASQFFAEVPMNLMKNKKAGYILTGQWAKKAFAEAKIYGEAVELAS
HCCCCCCEEEEEECCHHHHHHHHCHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
SADKTFSYIPDCSDLDIPEDLDYVYICENNTIYGTKYKTLPNTKGHILVSDVSSCFLSEP
CCCCHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCCCCCEEEEHHHHHHHCCC
MDVTKYGVVYGGVQKNIGPAGVVIAIIREDLITDDVLPGTPTMLKWKTQADADSLYNTPP
CCHHHHHEEECCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHCCCCC
CYNIYICGKVFKWIKKMGGLSAMKEHNEKKAKILYDFLDESKLFMGTVVKEDRSLMNVPF
CEEEEEHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCE
VCNIEDKEAKDAMEAKFIKEAAAAGFVNLKGHRTVGGMRASIYNAMPIEGVEKLVEFMKK
EEECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
FEKENA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]