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The map label for this gene is hipA [C]

Identifier: 238916523

GI number: 238916523

Start: 593024

End: 594316

Strand: Direct

Name: hipA [C]

Synonym: EUBELI_00580

Alternate gene names: 238916523

Gene position: 593024-594316 (Clockwise)

Preceding gene: 238916522

Following gene: 238916524

Centisome position: 27.66

GC content: 33.02

Gene sequence:

>1293_bases
ATGAGAAATTTAGAGGTATATATTGAATGTAATGGAAATATGATTAATGTTGGCAGTATTACAGGGCATAATTCTGACGA
TGCTGTATTTTCATATTCAGAGGAATATATAGAAGATAAATCTTCAAGATCAATATCAATCAGTTTACCGCTTGATGAAA
GAAGTTTTTCAGCGGAAAGAACGCGATGTTTCTTTGAAAGTCTTTTACCAGAAGGATATACAAGAAGGTGTGTTGCGGGT
TGGCTTCATGTCGATGAAAATGATTATATATCAGTTCTTTCAGAATTAGGAAGTGAGTGTCTCGGAGCAATAAGAATAGT
AGAAGGAGATATGAATATAAAACAATCTTCTTACAGATTATTATCACATGAGGAATTGCTGGAGTTTGCAAGAGAAGGTG
CAACTAAGTCAGCGGAACTGGTTATTAAATCACATTTATCATTAGCTGGGGCATCAGGAAAGACTGGATTATATTATGAC
AGGAATAATAATGAATGGTATCAGCCAGCGGGACTGGCACCAAGTACACATATATTAAAGCAGAGCCATGTAAGATTAAA
AAAGATAGTTGCTAATGAACAGTTATGTTTGCTGACAGCAAGAAAACTAGGAATTAGGACACCAGATAGTTTTATTATTA
ATCTTAATGATAAAGAAGATGATTTTTTATTTGCAACTGAAAGATATGACAGAAAGATTTTAGATACATCCAAAGAATTA
ATGGGGAAGAAAGTTCCATTAAGACTTCATCAGGAGGATTTTGCACAGGCACTTGGAATTACAGCGTCACAAAAATACGA
GAAAAACGGGAAAGATTATTTAGCAGAGGCATTTGAACTAATAAAAAATTATTCAAGCAATCCAATTGAAGATCAGATAA
GGCTATGGGATTTATGTATATTTAATTATCTTATAGGTAATACAGATAATCATGTTAAAAATATTGCTCTTTTATATAGT
GAGGATTTAAAAGGAATAAGATTAGCTCCGGCATATGATTTATTAAGTACTGTTATATATGACAGCAGCACAGAGAAAAT
GTCGCTTAACATAGATGGCGAATATGATATAAGGAATATAAATCAGAAGTCGTTTGAGAATGAGGCAAAGAAACTTGGTC
TTGGAAAAGGAATAGCAACGCAGCATTTTTTAAGTATGGTTGAAAAATTTGAGATGGCACTTGAACAATCAACATATGAA
CTTGAGGAGCAGGGATATGGAGTTGCAGTCGATATACAGAAACAAATATTAAAAAAAGCAGGAATTCACAACTTTAAATT
GACTAATCCGTAA

Upstream 100 bases:

>100_bases
CAGATGTGGAAAGAGGTAAGCCGACTGTTGAGATTGGCAAGGTAATACAGTTAATTTCGATTCTTGGACTTGATGTCAAT
ATTGATGTAAGGGGGAGATA

Downstream 100 bases:

>100_bases
TTTAATTATATCATAAGTAACTAGGGACACTTTGTTTCACTAAAGTATAATGGGAGGAAGTTATATGTATTCATTTGATG
AAGTATTAAACTATGATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRNLEVYIECNGNMINVGSITGHNSDDAVFSYSEEYIEDKSSRSISISLPLDERSFSAERTRCFFESLLPEGYTRRCVAG
WLHVDENDYISVLSELGSECLGAIRIVEGDMNIKQSSYRLLSHEELLEFAREGATKSAELVIKSHLSLAGASGKTGLYYD
RNNNEWYQPAGLAPSTHILKQSHVRLKKIVANEQLCLLTARKLGIRTPDSFIINLNDKEDDFLFATERYDRKILDTSKEL
MGKKVPLRLHQEDFAQALGITASQKYEKNGKDYLAEAFELIKNYSSNPIEDQIRLWDLCIFNYLIGNTDNHVKNIALLYS
EDLKGIRLAPAYDLLSTVIYDSSTEKMSLNIDGEYDIRNINQKSFENEAKKLGLGKGIATQHFLSMVEKFEMALEQSTYE
LEEQGYGVAVDIQKQILKKAGIHNFKLTNP

Sequences:

>Translated_430_residues
MRNLEVYIECNGNMINVGSITGHNSDDAVFSYSEEYIEDKSSRSISISLPLDERSFSAERTRCFFESLLPEGYTRRCVAG
WLHVDENDYISVLSELGSECLGAIRIVEGDMNIKQSSYRLLSHEELLEFAREGATKSAELVIKSHLSLAGASGKTGLYYD
RNNNEWYQPAGLAPSTHILKQSHVRLKKIVANEQLCLLTARKLGIRTPDSFIINLNDKEDDFLFATERYDRKILDTSKEL
MGKKVPLRLHQEDFAQALGITASQKYEKNGKDYLAEAFELIKNYSSNPIEDQIRLWDLCIFNYLIGNTDNHVKNIALLYS
EDLKGIRLAPAYDLLSTVIYDSSTEKMSLNIDGEYDIRNINQKSFENEAKKLGLGKGIATQHFLSMVEKFEMALEQSTYE
LEEQGYGVAVDIQKQILKKAGIHNFKLTNP
>Mature_430_residues
MRNLEVYIECNGNMINVGSITGHNSDDAVFSYSEEYIEDKSSRSISISLPLDERSFSAERTRCFFESLLPEGYTRRCVAG
WLHVDENDYISVLSELGSECLGAIRIVEGDMNIKQSSYRLLSHEELLEFAREGATKSAELVIKSHLSLAGASGKTGLYYD
RNNNEWYQPAGLAPSTHILKQSHVRLKKIVANEQLCLLTARKLGIRTPDSFIINLNDKEDDFLFATERYDRKILDTSKEL
MGKKVPLRLHQEDFAQALGITASQKYEKNGKDYLAEAFELIKNYSSNPIEDQIRLWDLCIFNYLIGNTDNHVKNIALLYS
EDLKGIRLAPAYDLLSTVIYDSSTEKMSLNIDGEYDIRNINQKSFENEAKKLGLGKGIATQHFLSMVEKFEMALEQSTYE
LEEQGYGVAVDIQKQILKKAGIHNFKLTNP

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=339, Percent_Identity=29.7935103244838, Blast_Score=141, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 48795; Mature: 48795

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLEVYIECNGNMINVGSITGHNSDDAVFSYSEEYIEDKSSRSISISLPLDERSFSAER
CCCEEEEEEECCCEEEECEECCCCCCCCEEECCHHHHCCCCCCEEEEEECCCCCCCCHHH
TRCFFESLLPEGYTRRCVAGWLHVDENDYISVLSELGSECLGAIRIVEGDMNIKQSSYRL
HHHHHHHHCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
LSHEELLEFAREGATKSAELVIKSHLSLAGASGKTGLYYDRNNNEWYQPAGLAPSTHILK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHH
QSHVRLKKIVANEQLCLLTARKLGIRTPDSFIINLNDKEDDFLFATERYDRKILDTSKEL
HHHHHHHHHHCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHCHHHH
MGKKVPLRLHQEDFAQALGITASQKYEKNGKDYLAEAFELIKNYSSNPIEDQIRLWDLCI
CCCCCCEEECHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FNYLIGNTDNHVKNIALLYSEDLKGIRLAPAYDLLSTVIYDSSTEKMSLNIDGEYDIRNI
HHHHHCCCCCHHHEEEEEEECCCCCEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
NQKSFENEAKKLGLGKGIATQHFLSMVEKFEMALEQSTYELEEQGYGVAVDIQKQILKKA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHC
GIHNFKLTNP
CCCCEEECCC
>Mature Secondary Structure
MRNLEVYIECNGNMINVGSITGHNSDDAVFSYSEEYIEDKSSRSISISLPLDERSFSAER
CCCEEEEEEECCCEEEECEECCCCCCCCEEECCHHHHCCCCCCEEEEEECCCCCCCCHHH
TRCFFESLLPEGYTRRCVAGWLHVDENDYISVLSELGSECLGAIRIVEGDMNIKQSSYRL
HHHHHHHHCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
LSHEELLEFAREGATKSAELVIKSHLSLAGASGKTGLYYDRNNNEWYQPAGLAPSTHILK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHH
QSHVRLKKIVANEQLCLLTARKLGIRTPDSFIINLNDKEDDFLFATERYDRKILDTSKEL
HHHHHHHHHHCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHCHHHH
MGKKVPLRLHQEDFAQALGITASQKYEKNGKDYLAEAFELIKNYSSNPIEDQIRLWDLCI
CCCCCCEEECHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FNYLIGNTDNHVKNIALLYSEDLKGIRLAPAYDLLSTVIYDSSTEKMSLNIDGEYDIRNI
HHHHHCCCCCHHHEEEEEEECCCCCEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
NQKSFENEAKKLGLGKGIATQHFLSMVEKFEMALEQSTYELEEQGYGVAVDIQKQILKKA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHC
GIHNFKLTNP
CCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]