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The map label for this gene is yacO [H]

Identifier: 238916436

GI number: 238916436

Start: 499878

End: 500618

Strand: Direct

Name: yacO [H]

Synonym: EUBELI_00492

Alternate gene names: 238916436

Gene position: 499878-500618 (Clockwise)

Preceding gene: 238916435

Following gene: 238916437

Centisome position: 23.31

GC content: 40.62

Gene sequence:

>741_bases
ATGAGATACAATGAATTAACATTTCAGGGAAGAAATGCTGTATTAGAGGCATTCCGCTCTGGTAAAACTATTGATAAGCT
TTTTATTCTTGACGGCTGTCAGGATGGACCAATAAAGAGTATTGTCAGAGAAGCAAAGAAAACAGATGCAATTATCAATT
ATGTTGATAAGGAAAGACTCGACAGACTTGCAGGAACAGGACATCATCAGGGTGTTGTTGCCATTGGTGCAGCTTATGAA
TATGCAGAGGTTGATGATATACTTGCATCAGCTAAGGAAAAGGGAGAAGATCCATTTATATTCATTCTTGATGAGATAGA
GGATCCTCACAATCTTGGTGCTATTATAAGAACTGCCAACCTTGCAGGTGCACATGGAGTTATTATTCCTAAGAGAAGAG
CTGTCGGACTTACAGCAACTGTAGCCAAGACATCAGCAGGCGCGATTAATTACACACCTGTAGCCAAGGTTACTAATATT
TCACAGACAATCGAGGAACTTAAGAAGCAGGGACTCTGGTTTGTATGCGCTGATATGGGCGGGGAGACAATGTATAATCT
TAATCTCAAAGGACCTATCGGCCTTGTTATAGGTAATGAGGGCAATGGAGTAAGCCGTCTTGTTAAGGATAAATGTGATT
TCATCGCATCAATTCCTATGAAGGGTGATATTGATTCCTTGAATGCCTCAGTTGCAGCAGGTGTTCTTGCATACGAAATA
GTCCGTCAGAGACTTAATTAG

Upstream 100 bases:

>100_bases
CAGGACTGGAAAGCCTTGAGTTAAAGTAGAGCCGGCAAAGCAGAATCCATATCTGTAATGGATAACTGGATTCTGCTTTG
TTAATATTAAGGAGAAATAT

Downstream 100 bases:

>100_bases
GGAGTTTTTTATGAAGCATATGGAAGAGTATCCTGATGAAGAGCTTATTGATATGTACAGGGCAGGTAATGAGCAGGCAA
TTGAGTACATATTTGAGAGA

Product: TrmH family RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRYNELTFQGRNAVLEAFRSGKTIDKLFILDGCQDGPIKSIVREAKKTDAIINYVDKERLDRLAGTGHHQGVVAIGAAYE
YAEVDDILASAKEKGEDPFIFILDEIEDPHNLGAIIRTANLAGAHGVIIPKRRAVGLTATVAKTSAGAINYTPVAKVTNI
SQTIEELKKQGLWFVCADMGGETMYNLNLKGPIGLVIGNEGNGVSRLVKDKCDFIASIPMKGDIDSLNASVAAGVLAYEI
VRQRLN

Sequences:

>Translated_246_residues
MRYNELTFQGRNAVLEAFRSGKTIDKLFILDGCQDGPIKSIVREAKKTDAIINYVDKERLDRLAGTGHHQGVVAIGAAYE
YAEVDDILASAKEKGEDPFIFILDEIEDPHNLGAIIRTANLAGAHGVIIPKRRAVGLTATVAKTSAGAINYTPVAKVTNI
SQTIEELKKQGLWFVCADMGGETMYNLNLKGPIGLVIGNEGNGVSRLVKDKCDFIASIPMKGDIDSLNASVAAGVLAYEI
VRQRLN
>Mature_246_residues
MRYNELTFQGRNAVLEAFRSGKTIDKLFILDGCQDGPIKSIVREAKKTDAIINYVDKERLDRLAGTGHHQGVVAIGAAYE
YAEVDDILASAKEKGEDPFIFILDEIEDPHNLGAIIRTANLAGAHGVIIPKRRAVGLTATVAKTSAGAINYTPVAKVTNI
SQTIEELKKQGLWFVCADMGGETMYNLNLKGPIGLVIGNEGNGVSRLVKDKCDFIASIPMKGDIDSLNASVAAGVLAYEI
VRQRLN

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=223, Percent_Identity=30.0448430493274, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790623, Length=237, Percent_Identity=37.1308016877637, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1790083, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788935, Length=245, Percent_Identity=25.3061224489796, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555908, Length=254, Percent_Identity=29.9212598425197, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324775, Length=164, Percent_Identity=34.7560975609756, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26572; Mature: 26572

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNELTFQGRNAVLEAFRSGKTIDKLFILDGCQDGPIKSIVREAKKTDAIINYVDKERL
CCCCCEEECCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DRLAGTGHHQGVVAIGAAYEYAEVDDILASAKEKGEDPFIFILDEIEDPHNLGAIIRTAN
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHEEECC
LAGAHGVIIPKRRAVGLTATVAKTSAGAINYTPVAKVTNISQTIEELKKQGLWFVCADMG
CCCCCCEEEECCCCCCEEEEEHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEEEECCC
GETMYNLNLKGPIGLVIGNEGNGVSRLVKDKCDFIASIPMKGDIDSLNASVAAGVLAYEI
CCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
VRQRLN
HHHHCC
>Mature Secondary Structure
MRYNELTFQGRNAVLEAFRSGKTIDKLFILDGCQDGPIKSIVREAKKTDAIINYVDKERL
CCCCCEEECCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DRLAGTGHHQGVVAIGAAYEYAEVDDILASAKEKGEDPFIFILDEIEDPHNLGAIIRTAN
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHEEECC
LAGAHGVIIPKRRAVGLTATVAKTSAGAINYTPVAKVTNISQTIEELKKQGLWFVCADMG
CCCCCCEEEECCCCCCEEEEEHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEEEECCC
GETMYNLNLKGPIGLVIGNEGNGVSRLVKDKCDFIASIPMKGDIDSLNASVAAGVLAYEI
CCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
VRQRLN
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]