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The map label for this gene is fchA [H]

Identifier: 238916380

GI number: 238916380

Start: 446958

End: 447587

Strand: Direct

Name: fchA [H]

Synonym: EUBELI_00434

Alternate gene names: 238916380

Gene position: 446958-447587 (Clockwise)

Preceding gene: 238916379

Following gene: 238916381

Centisome position: 20.85

GC content: 43.02

Gene sequence:

>630_bases
ATGATGACAGATATGACAATGGATAATTTCCTTGCGGTTTTATCTTCAAGTGAGCCGGTGCCGGGTGGCGGCGGAGCATG
CGGATATGTGGCAGCAGTAGGTATGAGCCTTGGTAATATGGTGCTGGCACTTACTACCGGAAAGAAGAAATACGCAGAGT
ATCAGGAAGAGATTGAAGAACTTATTGTTAAAGCTACAGATCTTACAAAGAGACTTGCAGAGTGCATGGATAAGGATGCA
GAGAGCTTTAAGCCTCTTGCAGCAGCTTATGGTCTTCCTAAGGATACAGAAGAACAGATTAAGGAAAGAGAAGCAATTAT
GGCAAAGGCACTTGTTACAGCCTCAGAAGCCCCTCTGTCAATGATGGAGCTTATACTTGAAGCCATGAAGCTTATCAACC
GTATATCTGTAATTGGAAGCAGAATTGCAATCAGTGATGCAGGTGTCGGCATAACAATGTGTGAGGCTGCAATGAAGGGT
GCTTCGCTTAACGTATTTATCAATACAAAGCTTATGAAGGACAGAGAACTTGCTGAAGATATGAACTTTAAGGCAGATAA
GATGCTTGCTGAAGCAGCACAGATTGAAGAAGAAACATTTGGAAGAGTTATGGACGCTGTAAGACCATAG

Upstream 100 bases:

>100_bases
CTTGGAGGTGACTTAAAGATTACATGGGATAAAGATGAGAATACCGTATATCTTGAAGGCCCGGCTAAAACAGTATTTAC
AGGGGAGGTAGATATTTAAT

Downstream 100 bases:

>100_bases
AACAGGATTGCAAAATAAGGAGGAAAATTCCTCTCCTCGCTGGGGGAGACAATGTGCTTAAAAAGCACATGGATTTTGCT
TCGCAAAACAAGGAGGAATA

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MMTDMTMDNFLAVLSSSEPVPGGGGACGYVAAVGMSLGNMVLALTTGKKKYAEYQEEIEELIVKATDLTKRLAECMDKDA
ESFKPLAAAYGLPKDTEEQIKEREAIMAKALVTASEAPLSMMELILEAMKLINRISVIGSRIAISDAGVGITMCEAAMKG
ASLNVFINTKLMKDRELAEDMNFKADKMLAEAAQIEEETFGRVMDAVRP

Sequences:

>Translated_209_residues
MMTDMTMDNFLAVLSSSEPVPGGGGACGYVAAVGMSLGNMVLALTTGKKKYAEYQEEIEELIVKATDLTKRLAECMDKDA
ESFKPLAAAYGLPKDTEEQIKEREAIMAKALVTASEAPLSMMELILEAMKLINRISVIGSRIAISDAGVGITMCEAAMKG
ASLNVFINTKLMKDRELAEDMNFKADKMLAEAAQIEEETFGRVMDAVRP
>Mature_209_residues
MMTDMTMDNFLAVLSSSEPVPGGGGACGYVAAVGMSLGNMVLALTTGKKKYAEYQEEIEELIVKATDLTKRLAECMDKDA
ESFKPLAAAYGLPKDTEEQIKEREAIMAKALVTASEAPLSMMELILEAMKLINRISVIGSRIAISDAGVGITMCEAAMKG
ASLNVFINTKLMKDRELAEDMNFKADKMLAEAAQIEEETFGRVMDAVRP

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22590; Mature: 22590

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
8.1 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
8.1 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDMTMDNFLAVLSSSEPVPGGGGACGYVAAVGMSLGNMVLALTTGKKKYAEYQEEIEE
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHH
LIVKATDLTKRLAECMDKDAESFKPLAAAYGLPKDTEEQIKEREAIMAKALVTASEAPLS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
MMELILEAMKLINRISVIGSRIAISDAGVGITMCEAAMKGASLNVFINTKLMKDRELAED
HHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
MNFKADKMLAEAAQIEEETFGRVMDAVRP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTDMTMDNFLAVLSSSEPVPGGGGACGYVAAVGMSLGNMVLALTTGKKKYAEYQEEIEE
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHH
LIVKATDLTKRLAECMDKDAESFKPLAAAYGLPKDTEEQIKEREAIMAKALVTASEAPLS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
MMELILEAMKLINRISVIGSRIAISDAGVGITMCEAAMKGASLNVFINTKLMKDRELAED
HHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
MNFKADKMLAEAAQIEEETFGRVMDAVRP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]