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The map label for this gene is yggV [C]

Identifier: 238916353

GI number: 238916353

Start: 421128

End: 421715

Strand: Direct

Name: yggV [C]

Synonym: EUBELI_00400

Alternate gene names: 238916353

Gene position: 421128-421715 (Clockwise)

Preceding gene: 238916352

Following gene: 238916354

Centisome position: 19.64

GC content: 38.95

Gene sequence:

>588_bases
ATGACTACTATTATTTTAGCGTCTAATAATAAGGACAAGGTTAAGGAAGTTAAAGAGATTCTTAAAGGGTATAATGTTAT
CTCTCTTAAGGATGCTGGAATTGACCTTGATGTGGAGGAAAATGGTACTACATTTGAAGAAAATGCGCTGATTAAGGCAA
GAGCTGTATGCAAACTTACAGGACAGCTTACAATGGCAGATGATTCAGGACTGGAGATTGATTATCTTAATAAAGAGCCT
GGCGTGTATTCTGCCAGATATATGGGACATGATACATCATATGATATTAAAAATGCTTCTCTTATTAAACGACTTGAGGG
TGTTGAAGGGCAGGACAGAAGCGGCAGGTTTGTATGTGCTATAGCAGTGTGTTTTCCTGATGGAAAGGAAATTGTTAAGA
GAGGCACAATGGAGGGACTTATAAGCAAGGAAATCGTCGGAGACAATGGTTTTGGCTATGACCCTATAGTTTATCTGCCC
GAATATGGTAAAACATCAGCACAGCTTGATCCTGAAGAGAAGAATAAGATAAGCCACAGAGGTAAGGCACTTGAACTTAT
AAAGAAAGAACTGGATGAGTGCCTCTAA

Upstream 100 bases:

>100_bases
ATAAGAATAGAAAGATATATAATGGAATGTTAAAGACATATTTTTACTCATTCCAGGGACCAAAGCCGCCTAAGAAAGAG
AAGGGACAGGAAAGATAATT

Downstream 100 bases:

>100_bases
TTGGCTCATTCTGGAGGTTTTATGCAGAGGATAATGATTGTTAGCGATTCACATAGAAGACACGGTAATCTGGCAGAGGC
AATATATAATGAGCAGCCAT

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTTIILASNNKDKVKEVKEILKGYNVISLKDAGIDLDVEENGTTFEENALIKARAVCKLTGQLTMADDSGLEIDYLNKEP
GVYSARYMGHDTSYDIKNASLIKRLEGVEGQDRSGRFVCAIAVCFPDGKEIVKRGTMEGLISKEIVGDNGFGYDPIVYLP
EYGKTSAQLDPEEKNKISHRGKALELIKKELDECL

Sequences:

>Translated_195_residues
MTTIILASNNKDKVKEVKEILKGYNVISLKDAGIDLDVEENGTTFEENALIKARAVCKLTGQLTMADDSGLEIDYLNKEP
GVYSARYMGHDTSYDIKNASLIKRLEGVEGQDRSGRFVCAIAVCFPDGKEIVKRGTMEGLISKEIVGDNGFGYDPIVYLP
EYGKTSAQLDPEEKNKISHRGKALELIKKELDECL
>Mature_194_residues
TTIILASNNKDKVKEVKEILKGYNVISLKDAGIDLDVEENGTTFEENALIKARAVCKLTGQLTMADDSGLEIDYLNKEPG
VYSARYMGHDTSYDIKNASLIKRLEGVEGQDRSGRFVCAIAVCFPDGKEIVKRGTMEGLISKEIVGDNGFGYDPIVYLPE
YGKTSAQLDPEEKNKISHRGKALELIKKELDECL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=42.7083333333333, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21555; Mature: 21424

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIILASNNKDKVKEVKEILKGYNVISLKDAGIDLDVEENGTTFEENALIKARAVCKLT
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEECCCCEEEHHEEEEEE
GQLTMADDSGLEIDYLNKEPGVYSARYMGHDTSYDIKNASLIKRLEGVEGQDRSGRFVCA
CEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE
IAVCFPDGKEIVKRGTMEGLISKEIVGDNGFGYDPIVYLPEYGKTSAQLDPEEKNKISHR
EEEECCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHC
GKALELIKKELDECL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTIILASNNKDKVKEVKEILKGYNVISLKDAGIDLDVEENGTTFEENALIKARAVCKLT
EEEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEECCCCEEEHHEEEEEE
GQLTMADDSGLEIDYLNKEPGVYSARYMGHDTSYDIKNASLIKRLEGVEGQDRSGRFVCA
CEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE
IAVCFPDGKEIVKRGTMEGLISKEIVGDNGFGYDPIVYLPEYGKTSAQLDPEEKNKISHR
EEEECCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHC
GKALELIKKELDECL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]