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The map label for this gene is yoeA [H]

Identifier: 238916257

GI number: 238916257

Start: 325365

End: 326705

Strand: Reverse

Name: yoeA [H]

Synonym: EUBELI_00291

Alternate gene names: 238916257

Gene position: 326705-325365 (Counterclockwise)

Preceding gene: 238916260

Following gene: 238916241

Centisome position: 15.24

GC content: 41.39

Gene sequence:

>1341_bases
ATGGTAAAAGACATGACAAATGGTTCGCCTTCCAAGCATATTCTTGGATTTGCAGTTCCAATGCTGTTCGGAATGCTGTT
TCAGCAGTTCTACAACCTTGTTGACACAATAATCGTTGGTAAAACTCTCGGTGTTGAAGCTCTTGCCGGAGTTGGAGCAA
CAGGTTCTATCAACTTCATGATAATCGGTTTCTGTATGGGAGTCTGTAACGGATTCGTGATTCCGGTTGCCCAATGCTTT
GGTGCAAAGAAGCCTGCTGACCTTAGAAAATATGTATTTAACGGATATATCTGCAGTATTGTGTTTGCCATAGTGCTTAC
GCTTGCATCCGTAATATTCTGCCGCAGGATACTTATTATCATGAATACACCGGCAGATATTATTGACCATGCCTATAATT
ACATAGTAGTTATATTCATAGGAATCCCAACTGTATTCCTGTACAACATGGTGTCCGGTGTTATCCGTTCGCTTGGCGAT
AGTAAGACACCTGTAGTTTTCCTTGTCCTTTCTTCAATAATAAATGTAGTACTTGATTTCTTTCTTATTCTTGTATGTAA
GATGGGTGTTGCCGGAGCTGGCTGGGCAACTGTAACATCACAGTTAATTTCGGGACTTACCTGCCTTATATATATGTATA
AGAAATATGACATCTTAAAAGGTGACAAATCAGAAAGGGTACTTGATAGAAGATTCATCACCAACCTGTGTATGAACGGT
GTTCCTATGGGACTCCAGTATTCAATAACAGCCATCGGAAGTACAATCCTTCAGGCTGCTGTCAATACACTTGGTTCAAC
ATATGTAGCCGCAATGACTGCCGGTTCTAAGATGTTTAACTTTACCTGTTGTCCATTTGATGCACTCGGCTCAACCATGG
CAACCTATGCCGGACAGAATGTTGGAGCTGCCAAGATTAAAAGACTTGGTCAGGGCGTACGCTCCGCTATGATAATCGGT
TCAGTATACAGTGTTCTTTCTCTTATTGCACTGTATTTCACTACAGATTATATTGCATTATTATTCGTTAATGCATCAGA
GACAACAATAATTGCTCTTACAAGACAGTTCATCCTTGCATCTGCATGCTTCTACATTCCGCTTACAGGTGTTAATGTAG
TCCGCTTCTGCATACAGGGTATGGGCTTCTCAGTATTTGCAATATCAGCTGGTATCTTAGAGATGATTGGCCGTGCATTT
GCAGCCATCATACTTATTCCAAGTATTGGATTCATGGGTGCATGCCTCGCCTCACCAATCGCTTGGATTGCTGCTGACGC
ATTTTTGTTTCCTGCATTCATACATTGTGCCAGGAAGCTTCATGCCAGACATTCTAAATAA

Upstream 100 bases:

>100_bases
TCGTTAAATTAATTCAAATTCGTGCAAAATCAGTTTGACAGTTTGTAAAAATATAGTATAATCATTTGGCTTTATAAATA
TACGAAAGTGAGGAAATCCT

Downstream 100 bases:

>100_bases
TTTTAAATATGCGAAATGCTGTCCGTCTTATTCAGACCGGACAGCATTTCGCATAATATCTATCTTGTAACATAAACAGC
TTGTCTCTTTAAAGAAACAT

Product: MATE family multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MVKDMTNGSPSKHILGFAVPMLFGMLFQQFYNLVDTIIVGKTLGVEALAGVGATGSINFMIIGFCMGVCNGFVIPVAQCF
GAKKPADLRKYVFNGYICSIVFAIVLTLASVIFCRRILIIMNTPADIIDHAYNYIVVIFIGIPTVFLYNMVSGVIRSLGD
SKTPVVFLVLSSIINVVLDFFLILVCKMGVAGAGWATVTSQLISGLTCLIYMYKKYDILKGDKSERVLDRRFITNLCMNG
VPMGLQYSITAIGSTILQAAVNTLGSTYVAAMTAGSKMFNFTCCPFDALGSTMATYAGQNVGAAKIKRLGQGVRSAMIIG
SVYSVLSLIALYFTTDYIALLFVNASETTIIALTRQFILASACFYIPLTGVNVVRFCIQGMGFSVFAISAGILEMIGRAF
AAIILIPSIGFMGACLASPIAWIAADAFLFPAFIHCARKLHARHSK

Sequences:

>Translated_446_residues
MVKDMTNGSPSKHILGFAVPMLFGMLFQQFYNLVDTIIVGKTLGVEALAGVGATGSINFMIIGFCMGVCNGFVIPVAQCF
GAKKPADLRKYVFNGYICSIVFAIVLTLASVIFCRRILIIMNTPADIIDHAYNYIVVIFIGIPTVFLYNMVSGVIRSLGD
SKTPVVFLVLSSIINVVLDFFLILVCKMGVAGAGWATVTSQLISGLTCLIYMYKKYDILKGDKSERVLDRRFITNLCMNG
VPMGLQYSITAIGSTILQAAVNTLGSTYVAAMTAGSKMFNFTCCPFDALGSTMATYAGQNVGAAKIKRLGQGVRSAMIIG
SVYSVLSLIALYFTTDYIALLFVNASETTIIALTRQFILASACFYIPLTGVNVVRFCIQGMGFSVFAISAGILEMIGRAF
AAIILIPSIGFMGACLASPIAWIAADAFLFPAFIHCARKLHARHSK
>Mature_446_residues
MVKDMTNGSPSKHILGFAVPMLFGMLFQQFYNLVDTIIVGKTLGVEALAGVGATGSINFMIIGFCMGVCNGFVIPVAQCF
GAKKPADLRKYVFNGYICSIVFAIVLTLASVIFCRRILIIMNTPADIIDHAYNYIVVIFIGIPTVFLYNMVSGVIRSLGD
SKTPVVFLVLSSIINVVLDFFLILVCKMGVAGAGWATVTSQLISGLTCLIYMYKKYDILKGDKSERVLDRRFITNLCMNG
VPMGLQYSITAIGSTILQAAVNTLGSTYVAAMTAGSKMFNFTCCPFDALGSTMATYAGQNVGAAKIKRLGQGVRSAMIIG
SVYSVLSLIALYFTTDYIALLFVNASETTIIALTRQFILASACFYIPLTGVNVVRFCIQGMGFSVFAISAGILEMIGRAF
AAIILIPSIGFMGACLASPIAWIAADAFLFPAFIHCARKLHARHSK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=338, Percent_Identity=23.0769230769231, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48007; Mature: 48007

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]