Click here to switch to the map view.

The map label for this gene is gatD [H]

Identifier: 238916228

GI number: 238916228

Start: 292365

End: 293381

Strand: Direct

Name: gatD [H]

Synonym: EUBELI_00262

Alternate gene names: 238916228

Gene position: 292365-293381 (Clockwise)

Preceding gene: 238916227

Following gene: 238916229

Centisome position: 13.64

GC content: 35.59

Gene sequence:

>1017_bases
ATGATGAAAGCACAAGTGTTATATGGCATGGGTGATTTAAGATATAAGGATATAGAGAAACCACAGCTTAAAGAGGGCTG
GGTAATGGTTAAGGTTATGGCAGCAGGCGTATGTGGTTCTGATATTCCAAGAATATATAATACAGGAGCACATGTTCATC
CTATTGTTCCTGGACATGAATTTTCAGGTGAAGTAGTAGAAACATTTGATAAGAACTCCCGATGGAATGGAAAAAGAGTC
GGAGTATTTCCTTTGATTCCATGTGGAAAATGTTCAAGCTGTAAAAAGAAAATGTATGAGATGTGCAGTAATTATAACTA
TCTTGGTTCAAGATGTGATGGCGGTTTTGCAGAATATGCTGCTGTACCAGAGTGGAATCTTATAGAGCTTCCAGATAATG
TGACATACAGGCAGGCTGCAATGATGGAACCAATGGCAGTTGCAGTACACGCAATGAGAAGATTTAGTATATCGAAGGAT
TCAACAGTGTGTGTTATTGGACTTGGTACGATAGGATTGCTTCTTACAATGTTTCTTAAATCAGAAGGCATAGAAAATGT
ATATGTATTTGGCAATAAAGATGTGCAAAGAGACTATGCAAGGAAATTGGGCATTGATGATGAATGTTATAATGCCAAAC
ATATAAGTGCAGATTATGTATTTGAGTGTGTTGGAAAGAATGAAACTGTCAATCAGGCAATAGAATTAGCAGCACCAGCT
GGACATATTACTATGGTTGGAAATCCTTATTCTGATATGGAGATTTCTAAAGATTTATATTGGAAAATATTAAGAAAGCA
ATTAAAAATAAGCGGAACATGGAATTCATCATATACAGGAGATGTTAATGATGACTGGCATTTTGTGCTTAATAAGCTTG
AAAAAGCGGAAATTGATCCAGAAAGATTTATAACGCATGAATATTCTATAGACGGTATACAGACGGGAATGAAAATTATG
CGGGATAAGTCAGAAGATTATGTGAAAGTTATATGTATTGATGAAGAGGACTTTTAA

Upstream 100 bases:

>100_bases
TGTTATGATTCCGGGAGACGAGAATAATTATAAGATAACTACGAAGACAGATATGAAGCGGTTCACAGAAATGATGTAGA
TTTATTTTTTCAGGAGAAAA

Downstream 100 bases:

>100_bases
TGATAAGAGTTGATATATTATCTCCAGTGGGTGGGAAAGTCGGGGGAATAGAGAATGTTATTAAGTTATGGACAAAGAAT
CTGTCGCAGCCAGATTATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMKAQVLYGMGDLRYKDIEKPQLKEGWVMVKVMAAGVCGSDIPRIYNTGAHVHPIVPGHEFSGEVVETFDKNSRWNGKRV
GVFPLIPCGKCSSCKKKMYEMCSNYNYLGSRCDGGFAEYAAVPEWNLIELPDNVTYRQAAMMEPMAVAVHAMRRFSISKD
STVCVIGLGTIGLLLTMFLKSEGIENVYVFGNKDVQRDYARKLGIDDECYNAKHISADYVFECVGKNETVNQAIELAAPA
GHITMVGNPYSDMEISKDLYWKILRKQLKISGTWNSSYTGDVNDDWHFVLNKLEKAEIDPERFITHEYSIDGIQTGMKIM
RDKSEDYVKVICIDEEDF

Sequences:

>Translated_338_residues
MMKAQVLYGMGDLRYKDIEKPQLKEGWVMVKVMAAGVCGSDIPRIYNTGAHVHPIVPGHEFSGEVVETFDKNSRWNGKRV
GVFPLIPCGKCSSCKKKMYEMCSNYNYLGSRCDGGFAEYAAVPEWNLIELPDNVTYRQAAMMEPMAVAVHAMRRFSISKD
STVCVIGLGTIGLLLTMFLKSEGIENVYVFGNKDVQRDYARKLGIDDECYNAKHISADYVFECVGKNETVNQAIELAAPA
GHITMVGNPYSDMEISKDLYWKILRKQLKISGTWNSSYTGDVNDDWHFVLNKLEKAEIDPERFITHEYSIDGIQTGMKIM
RDKSEDYVKVICIDEEDF
>Mature_338_residues
MMKAQVLYGMGDLRYKDIEKPQLKEGWVMVKVMAAGVCGSDIPRIYNTGAHVHPIVPGHEFSGEVVETFDKNSRWNGKRV
GVFPLIPCGKCSSCKKKMYEMCSNYNYLGSRCDGGFAEYAAVPEWNLIELPDNVTYRQAAMMEPMAVAVHAMRRFSISKD
STVCVIGLGTIGLLLTMFLKSEGIENVYVFGNKDVQRDYARKLGIDDECYNAKHISADYVFECVGKNETVNQAIELAAPA
GHITMVGNPYSDMEISKDLYWKILRKQLKISGTWNSSYTGDVNDDWHFVLNKLEKAEIDPERFITHEYSIDGIQTGMKIM
RDKSEDYVKVICIDEEDF

Specific function: Converts galactitol 1-phosphate to tagatose 6-phosphate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=327, Percent_Identity=24.4648318042813, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1788407, Length=346, Percent_Identity=30.635838150289, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787863, Length=346, Percent_Identity=29.4797687861272, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790045, Length=324, Percent_Identity=30.8641975308642, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788073, Length=345, Percent_Identity=26.0869565217391, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI226510992, Length=311, Percent_Identity=27.3311897106109, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788075, Length=365, Percent_Identity=27.9452054794521, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082125, Length=328, Percent_Identity=26.5243902439024, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790718, Length=316, Percent_Identity=23.7341772151899, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786825, Length=395, Percent_Identity=24.5569620253165, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786552, Length=368, Percent_Identity=23.0978260869565, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=275, Percent_Identity=30.5454545454545, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562878, Length=211, Percent_Identity=31.7535545023697, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322619, Length=339, Percent_Identity=27.7286135693215, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319955, Length=339, Percent_Identity=27.7286135693215, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319257, Length=387, Percent_Identity=27.1317829457364, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323099, Length=332, Percent_Identity=28.3132530120482, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=387, Percent_Identity=24.5478036175711, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737897, Length=349, Percent_Identity=23.7822349570201, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137530, Length=347, Percent_Identity=23.9193083573487, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.251 [H]

Molecular weight: Translated: 38224; Mature: 38224

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKAQVLYGMGDLRYKDIEKPQLKEGWVMVKVMAAGVCGSDIPRIYNTGAHVHPIVPGHE
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCEEEECCCCCC
FSGEVVETFDKNSRWNGKRVGVFPLIPCGKCSSCKKKMYEMCSNYNYLGSRCDGGFAEYA
CCCHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
AVPEWNLIELPDNVTYRQAAMMEPMAVAVHAMRRFSISKDSTVCVIGLGTIGLLLTMFLK
CCCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHH
SEGIENVYVFGNKDVQRDYARKLGIDDECYNAKHISADYVFECVGKNETVNQAIELAAPA
HCCCCEEEEECCCHHHHHHHHHCCCCCHHCCCCCCCHHHHEEECCCCCHHHHHHHHCCCC
GHITMVGNPYSDMEISKDLYWKILRKQLKISGTWNSSYTGDVNDDWHFVLNKLEKAEIDP
CCEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCH
ERFITHEYSIDGIQTGMKIMRDKSEDYVKVICIDEEDF
HHHEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MMKAQVLYGMGDLRYKDIEKPQLKEGWVMVKVMAAGVCGSDIPRIYNTGAHVHPIVPGHE
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCEEEECCCCCC
FSGEVVETFDKNSRWNGKRVGVFPLIPCGKCSSCKKKMYEMCSNYNYLGSRCDGGFAEYA
CCCHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
AVPEWNLIELPDNVTYRQAAMMEPMAVAVHAMRRFSISKDSTVCVIGLGTIGLLLTMFLK
CCCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHH
SEGIENVYVFGNKDVQRDYARKLGIDDECYNAKHISADYVFECVGKNETVNQAIELAAPA
HCCCCEEEEECCCHHHHHHHHHCCCCCHHCCCCCCCHHHHEEECCCCCHHHHHHHHCCCC
GHITMVGNPYSDMEISKDLYWKILRKQLKISGTWNSSYTGDVNDDWHFVLNKLEKAEIDP
CCEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCH
ERFITHEYSIDGIQTGMKIMRDKSEDYVKVICIDEEDF
HHHEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]