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The map label for this gene is tig [H]

Identifier: 238916134

GI number: 238916134

Start: 194977

End: 196194

Strand: Direct

Name: tig [H]

Synonym: EUBELI_00168

Alternate gene names: 238916134

Gene position: 194977-196194 (Clockwise)

Preceding gene: 238916131

Following gene: 238916135

Centisome position: 9.09

GC content: 35.22

Gene sequence:

>1218_bases
ATGTTTATGTATATAGAAACGAGGAAGTATATGAAAAAGAAATTATTCAGTGTGTTACTTGTTGGTGCACTTGCAGCATC
TTTAGTAGCATGTGATTCAAAAAAGAAGGAAGTTGATAAGACACCTTCGACAGTCAACACAGAGATAAATGCAGATGAAT
ATGCTGCAACAATTACAGATAATGCTGGTATATATAAGACATTTGTATCACTTTCAGATTGGAAAGGAATGTCAGTAGAC
CTGGCAGAATCTGATTATAAAGTAACTGATTCAGATGTTGAGGATTATATACAGAGCCTTCTGGAGGCAACTGCAACTAC
AGATGCCCAGACAACAGGTACTACAAAGTCAGGTGATACAATTAAGCTTGATTATAGCGGAAAGCTTGACGGAACAGCAT
TTTCAGGTGGAACAGCAACAGATGCTTCTTACACAATTGGTTCAGGTAAATTTATCGATGATCTTGATAAAGGACTTGTT
GGACTTACAGTTGGTGTAGAGACAGATATTCCATGTACATTCCCTGAAAGCTACCAGAATTCAGACCTTGCCGGAAAGCA
GGTCGTATTTACAGTAACTGTAAAGGAAATTGATGTAACAGTTGTTCCGGAGCTTAATGATGAATGGGTAACAGCTAATG
CATCAAAATTAGGTGTTTCGGATGCTGAACTTACAAATGTTGAGGATTTAAGAGCATATGTTAAGAATTACCTTGAAACA
CAGGCAGCGTCTAACAGATCAAGTACAGTATTTGAGACTGCTTATTCACAGATGTCAGATGGTCTTGATGTTTCAGAATA
TCCAAGCGAAGAGCTTGCAGACCTTTTGAAAACACTTAATAATAATGTTGATTCAGAGTATCAGTCATACAGTTCATCAT
ATTCATCAAAGGAAGATTATCTTAAGAGTGCATATAATTTTGATTCTCTGGATGCATTTAACGAATATGCAGACAATTAT
GCAAAGCAATATCTTTTACAGAAAATGATTATTACAATGATTGCTGCTGATAATAATATTACAGTTAGTGCGGATGATAT
TAATTCAACAGGTGAAGAACTTGCTTCTTATTATGGATATAATGATTATCAGGAAATTCTTGATACCTATGGAAAGACAA
TGAATGCAGAGATAGGATATCAGGTACTTTATCAGAAGGTTGTTGAGTTTGTATGTGATAATGTAACAATTAATGATACA
TCTTCAACAGAACAGTAA

Upstream 100 bases:

>100_bases
TAACAGTTTAATGCTGTATAAAAAAGTGAAATTAGTGTGAAATTACTTTTATTTTTATCGTAAATGTGCTATAAATATAA
GGCTTGCTGTTAAGCAGCTA

Downstream 100 bases:

>100_bases
TCGTGACTAATTAAATATTAATATGATTGACAGGACTAGGGTTGCACAGCTATTAATGGGTGTGCAGCCTTATTTATTCT
TATTATTTCCGCATTAAAAC

Product: peptidylprolyl isomerase

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MFMYIETRKYMKKKLFSVLLVGALAASLVACDSKKKEVDKTPSTVNTEINADEYAATITDNAGIYKTFVSLSDWKGMSVD
LAESDYKVTDSDVEDYIQSLLEATATTDAQTTGTTKSGDTIKLDYSGKLDGTAFSGGTATDASYTIGSGKFIDDLDKGLV
GLTVGVETDIPCTFPESYQNSDLAGKQVVFTVTVKEIDVTVVPELNDEWVTANASKLGVSDAELTNVEDLRAYVKNYLET
QAASNRSSTVFETAYSQMSDGLDVSEYPSEELADLLKTLNNNVDSEYQSYSSSYSSKEDYLKSAYNFDSLDAFNEYADNY
AKQYLLQKMIITMIAADNNITVSADDINSTGEELASYYGYNDYQEILDTYGKTMNAEIGYQVLYQKVVEFVCDNVTINDT
SSTEQ

Sequences:

>Translated_405_residues
MFMYIETRKYMKKKLFSVLLVGALAASLVACDSKKKEVDKTPSTVNTEINADEYAATITDNAGIYKTFVSLSDWKGMSVD
LAESDYKVTDSDVEDYIQSLLEATATTDAQTTGTTKSGDTIKLDYSGKLDGTAFSGGTATDASYTIGSGKFIDDLDKGLV
GLTVGVETDIPCTFPESYQNSDLAGKQVVFTVTVKEIDVTVVPELNDEWVTANASKLGVSDAELTNVEDLRAYVKNYLET
QAASNRSSTVFETAYSQMSDGLDVSEYPSEELADLLKTLNNNVDSEYQSYSSSYSSKEDYLKSAYNFDSLDAFNEYADNY
AKQYLLQKMIITMIAADNNITVSADDINSTGEELASYYGYNDYQEILDTYGKTMNAEIGYQVLYQKVVEFVCDNVTINDT
SSTEQ
>Mature_405_residues
MFMYIETRKYMKKKLFSVLLVGALAASLVACDSKKKEVDKTPSTVNTEINADEYAATITDNAGIYKTFVSLSDWKGMSVD
LAESDYKVTDSDVEDYIQSLLEATATTDAQTTGTTKSGDTIKLDYSGKLDGTAFSGGTATDASYTIGSGKFIDDLDKGLV
GLTVGVETDIPCTFPESYQNSDLAGKQVVFTVTVKEIDVTVVPELNDEWVTANASKLGVSDAELTNVEDLRAYVKNYLET
QAASNRSSTVFETAYSQMSDGLDVSEYPSEELADLLKTLNNNVDSEYQSYSSSYSSKEDYLKSAYNFDSLDAFNEYADNY
AKQYLLQKMIITMIAADNNITVSADDINSTGEELASYYGYNDYQEILDTYGKTMNAEIGYQVLYQKVVEFVCDNVTINDT
SSTEQ

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=295, Percent_Identity=24.406779661017, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 44533; Mature: 44533

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS50059 FKBP_PPIASE ; PS00283 SOYBEAN_KUNITZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMYIETRKYMKKKLFSVLLVGALAASLVACDSKKKEVDKTPSTVNTEINADEYAATITD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHEEEEEC
NAGIYKTFVSLSDWKGMSVDLAESDYKVTDSDVEDYIQSLLEATATTDAQTTGTTKSGDT
CCCHHHHHHHHHCCCCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
IKLDYSGKLDGTAFSGGTATDASYTIGSGKFIDDLDKGLVGLTVGVETDIPCTFPESYQN
EEEEECCCCCCCEECCCCCCCCCEECCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
SDLAGKQVVFTVTVKEIDVTVVPELNDEWVTANASKLGVSDAELTNVEDLRAYVKNYLET
CCCCCCEEEEEEEEEEEEEEEECCCCCCEEECCCHHCCCCHHHHCCHHHHHHHHHHHHHH
QAASNRSSTVFETAYSQMSDGLDVSEYPSEELADLLKTLNNNVDSEYQSYSSSYSSKEDY
HHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
LKSAYNFDSLDAFNEYADNYAKQYLLQKMIITMIAADNNITVSADDINSTGEELASYYGY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
NDYQEILDTYGKTMNAEIGYQVLYQKVVEFVCDNVTINDTSSTEQ
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure
MFMYIETRKYMKKKLFSVLLVGALAASLVACDSKKKEVDKTPSTVNTEINADEYAATITD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHEEEEEC
NAGIYKTFVSLSDWKGMSVDLAESDYKVTDSDVEDYIQSLLEATATTDAQTTGTTKSGDT
CCCHHHHHHHHHCCCCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
IKLDYSGKLDGTAFSGGTATDASYTIGSGKFIDDLDKGLVGLTVGVETDIPCTFPESYQN
EEEEECCCCCCCEECCCCCCCCCEECCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
SDLAGKQVVFTVTVKEIDVTVVPELNDEWVTANASKLGVSDAELTNVEDLRAYVKNYLET
CCCCCCEEEEEEEEEEEEEEEECCCCCCEEECCCHHCCCCHHHHCCHHHHHHHHHHHHHH
QAASNRSSTVFETAYSQMSDGLDVSEYPSEELADLLKTLNNNVDSEYQSYSSSYSSKEDY
HHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
LKSAYNFDSLDAFNEYADNYAKQYLLQKMIITMIAADNNITVSADDINSTGEELASYYGY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
NDYQEILDTYGKTMNAEIGYQVLYQKVVEFVCDNVTINDTSSTEQ
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA