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The map label for this gene is yhdG [H]

Identifier: 238916073

GI number: 238916073

Start: 117893

End: 119368

Strand: Direct

Name: yhdG [H]

Synonym: EUBELI_00106

Alternate gene names: 238916073

Gene position: 117893-119368 (Clockwise)

Preceding gene: 238916072

Following gene: 238916074

Centisome position: 5.5

GC content: 37.33

Gene sequence:

>1476_bases
ATGAACGAGAATAATCAGCTGGTTCGTGCTTTAGGGCTTAAAGAATCAATTAGTATGACAATTGGAACAGTTGTAGGTGT
AGGACTTTTTACCTGTGGTTCAGCACAGATAGGAAGTGTAGGATCATGGATAATAGGATTCACATTTGTTGCACTTCTTA
TATCTATATGGCCATGTCTTATATATGGAGAGATGTCTGCAGCACTTCCTTGTGCGGGTGGAACATATAATTATGCCAAG
AGAGGACTTAACAGAGTATGGGCTAATATGGCAGGATGGCATTATATAGTATCTGTTGTAGCTATTGGTGCAGGTGAGAC
GCTTGCATTTGCCAATTATTTTAAGATTCTTATGGAACAGCTTGGAATAAGCATTGTTAAGCTTGATTCAAGAATTATAG
CTATTATCCTTGTTGCAGTTTTCCTTATTCTTAATTTCAGAGGTATTGAGCAGTCAGGTAAGGCACAGACAGCATTTATG
TTTTTCTTCTGGGGCTGTTCAGTGTGCTGGTTCCTTTATATGATACCTAAGGTTCATGTTGAATATTTTGGTGGAATAGC
AATGAACTCATTGCCTCCATTTAATGAGATGATGTATATATTTGGTCTTGTATGGTGGTGCTATACAGGATTTGAGACAT
GTGTATCTATGGGTGCAGAGACTAAGTACCCACAGTATACACTTCCAAGAGCATTAAAGATTTCGGTATTTATGGTATTT
GCACTTAACGCATTATTCCAGTGGTTTCTTGTAGGTCTTGTACCTAAGGAGTTTTATGGAATTCTCGCAGCGGCAGATGC
TCCATATGCAGAAGGACTTAAGGCGGTCGGACTTGTTGGATTTCCTATTATACTTTTATGTATCGGTATTGCATTTGGTG
GTGATTTATCTACTATTAATCCAGGAATTGCTGCACCTGCAAGATACATTTATACAATGGCAGAAGATGGCGCATTACCA
AAATTCCTTGGAAAGATTCATCCAAAGTTCAAGACACCATATGTTGCTGTTATTGTGGTTGGTGTTATCAATTTTATACT
TATTGCAACAGGTTCAATTAATTACATAGCGTCAGTATCGCTTATATCACTTGCTATATGTTATATGATAGGCTGTCTTT
CATATATGGGGCTTAAGAAGAAGTATCCTGATATGAAGAGACCTTATAAAGCACCTCTTGGAGTTGTTGGATGTATATTT
ACAATTGTTGTGTATTGCTTCATGTTAATATTTGCGGATAAGGCAGCACTTATTACATCAGGAATCATAACAGTATTATG
TGTAATATTTTATTTTGCATATTCTCACAGAAAAGAGTGTGTTATGCCGACAATTGAGGAAGAAATTGGCGTTATAGAAG
AGCCGGATGAGCAGACTAAGGCTAAGATGGACAGACAGTACACCATATGGAAGGTATGCACAATTATTGTTACATGCATT
GCACTTGGAATCTATATAATTCCAATGGTGCTGTAA

Upstream 100 bases:

>100_bases
TTTATACTGGTAATTTAGTTTATTATCTGATATAATCCATTTTGTTCACGCAGATGGACAAAAATATGACCGAATGAATA
AACTGTGAGAGGGGATATTT

Downstream 100 bases:

>100_bases
GGAGGAAATATGAATCGTTATCAGTTTGAAGTACTTACATATATTGAAAAGAATGGTAAGAAAGATTATCCGATGAGAAC
TCTTTCAGATACATTAAAGA

Product: APA family basic amino acid/polyamine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNENNQLVRALGLKESISMTIGTVVGVGLFTCGSAQIGSVGSWIIGFTFVALLISIWPCLIYGEMSAALPCAGGTYNYAK
RGLNRVWANMAGWHYIVSVVAIGAGETLAFANYFKILMEQLGISIVKLDSRIIAIILVAVFLILNFRGIEQSGKAQTAFM
FFFWGCSVCWFLYMIPKVHVEYFGGIAMNSLPPFNEMMYIFGLVWWCYTGFETCVSMGAETKYPQYTLPRALKISVFMVF
ALNALFQWFLVGLVPKEFYGILAAADAPYAEGLKAVGLVGFPIILLCIGIAFGGDLSTINPGIAAPARYIYTMAEDGALP
KFLGKIHPKFKTPYVAVIVVGVINFILIATGSINYIASVSLISLAICYMIGCLSYMGLKKKYPDMKRPYKAPLGVVGCIF
TIVVYCFMLIFADKAALITSGIITVLCVIFYFAYSHRKECVMPTIEEEIGVIEEPDEQTKAKMDRQYTIWKVCTIIVTCI
ALGIYIIPMVL

Sequences:

>Translated_491_residues
MNENNQLVRALGLKESISMTIGTVVGVGLFTCGSAQIGSVGSWIIGFTFVALLISIWPCLIYGEMSAALPCAGGTYNYAK
RGLNRVWANMAGWHYIVSVVAIGAGETLAFANYFKILMEQLGISIVKLDSRIIAIILVAVFLILNFRGIEQSGKAQTAFM
FFFWGCSVCWFLYMIPKVHVEYFGGIAMNSLPPFNEMMYIFGLVWWCYTGFETCVSMGAETKYPQYTLPRALKISVFMVF
ALNALFQWFLVGLVPKEFYGILAAADAPYAEGLKAVGLVGFPIILLCIGIAFGGDLSTINPGIAAPARYIYTMAEDGALP
KFLGKIHPKFKTPYVAVIVVGVINFILIATGSINYIASVSLISLAICYMIGCLSYMGLKKKYPDMKRPYKAPLGVVGCIF
TIVVYCFMLIFADKAALITSGIITVLCVIFYFAYSHRKECVMPTIEEEIGVIEEPDEQTKAKMDRQYTIWKVCTIIVTCI
ALGIYIIPMVL
>Mature_491_residues
MNENNQLVRALGLKESISMTIGTVVGVGLFTCGSAQIGSVGSWIIGFTFVALLISIWPCLIYGEMSAALPCAGGTYNYAK
RGLNRVWANMAGWHYIVSVVAIGAGETLAFANYFKILMEQLGISIVKLDSRIIAIILVAVFLILNFRGIEQSGKAQTAFM
FFFWGCSVCWFLYMIPKVHVEYFGGIAMNSLPPFNEMMYIFGLVWWCYTGFETCVSMGAETKYPQYTLPRALKISVFMVF
ALNALFQWFLVGLVPKEFYGILAAADAPYAEGLKAVGLVGFPIILLCIGIAFGGDLSTINPGIAAPARYIYTMAEDGALP
KFLGKIHPKFKTPYVAVIVVGVINFILIATGSINYIASVSLISLAICYMIGCLSYMGLKKKYPDMKRPYKAPLGVVGCIF
TIVVYCFMLIFADKAALITSGIITVLCVIFYFAYSHRKECVMPTIEEEIGVIEEPDEQTKAKMDRQYTIWKVCTIIVTCI
ALGIYIIPMVL

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI7657683, Length=423, Percent_Identity=24.822695035461, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082250, Length=408, Percent_Identity=25.4901960784314, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786602, Length=478, Percent_Identity=21.9665271966527, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082023, Length=329, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367353, Length=462, Percent_Identity=21.4285714285714, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=367, Percent_Identity=24.7956403269755, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321629, Length=456, Percent_Identity=21.2719298245614, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357367, Length=455, Percent_Identity=23.2967032967033, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24666159, Length=410, Percent_Identity=21.4634146341463, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221512776, Length=410, Percent_Identity=21.4634146341463, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550968, Length=467, Percent_Identity=25.0535331905782, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921172, Length=467, Percent_Identity=25.0535331905782, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54083; Mature: 54083

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]