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The map label for this gene is murA2 [H]

Identifier: 238916036

GI number: 238916036

Start: 73740

End: 75035

Strand: Direct

Name: murA2 [H]

Synonym: EUBELI_00069

Alternate gene names: 238916036

Gene position: 73740-75035 (Clockwise)

Preceding gene: 238916035

Following gene: 238916037

Centisome position: 3.44

GC content: 39.81

Gene sequence:

>1296_bases
ATGGAACAATATGTTGTCAAGGGTGGAGTGCCACTCAGAGGAAAAGTTTCCATTGGTGGTGCGAAGAATGCAGCTTTAGG
TATTCTTGCAGCAGCAATTATGACAGATGATACTGTAACAATTGAAAATGTACCTAATGTTAGAGACACAAGAGTTTTAC
TTCAGGCTATAGAAGGAATTGGTGCTAAGGTTAAGTATGTTTATAACAATTCCGTTCAGATAAATGGTGGTTCAATCTGT
GATACCAATGTAGAATATGATTATATAAGAAAAATAAGAGCATCTTACTATCTGTTAGGTGCTTTACTTGGTAAGTACAA
TGAGGCTCATGTTGCACTCCCAGGAGGATGCAATATCGGAAGCCGTCCAATTGACCAGCATATCAAGGGCTTTAAGGCAC
TTGGTGCGGATGTTGATATAGATTGTGGAGTTGTACATGCAAAGGCAGAGAAGCTTACAGGAGCTCATGTTTATTTTGAT
GTTGTAACAGTTGGTGCAACAATTAACCTTATGATGGCTTCATGTATGGCAGAGGGAGACACTATTCTGGAAAATGCGGC
TAAGGAACCGCATATAGTTGATGTAGCGAATTTCCTTAATTCTATGGGTGCTAACATTAAAGGTGCAGGAACTGATGTAA
TCCGTATCAAAGGCGTTAAGAGACTTCACGGATGTACTTATTCTATTATTCCGGATCAGATTGAGGCCGGAACATTTATG
ATGGCAGCAGCAGCTACACATGGTGATGTTGTTATTCAGGATATTATTCCTAAGCATATGGAATCAATATCTGCAAAGTT
AATTGAGATGGGATGCAGGATTGAGGAAGGTGATGACAGCTTAAGAGTTATAGCAGAGGGCTGTACACTTAGGAGTACTA
ATGTTAAGACTTTGCCATATCCTGGATTTCCAACGGATATGCAGCCACAGATTTCAGTTGTACTTGCACTTGCTGAAGGT
TCAAGTATGGTAACTGAGAGCATATTTGAGAACAGATTCAAATATGTAGATGAGCTTGGAAGAATGGGTGCCAAGATTAA
GGTTGAGGGTAACACAGCCTATATTGAAGGTGTTAAAAGTTTTTGTGGTGTGCAGCTTAATGCTCCGGATTTAAGAGCTG
GTGCGGCACTTGTTATTGCTGCGCTCGCAGCAGATGGTATATCAGAGATTGATGATATTGAGTATATCCAGAGAGGTTAT
GAGGATTTTGAAGGAAAGATTACTAACCTTGGTGGAATTATTAAAAGAGTTGATTCAGAGAGAGAACTTCAGAAGTTCAG
GCTCAAGATAGGTTAA

Upstream 100 bases:

>100_bases
TTGCCATATTTTTATAAATGTATTTGCAACGAAAATCTTTACAAATCAAAGTTCTGTGATATACTTTATAAGATGTGACT
ATTATGTTTAGAGGTGCTAT

Downstream 100 bases:

>100_bases
TTGCAGGCTGTAGCGGATATTCCGTTACAGCTGTTTTAATTTATATTTAATAAAATTAATACATTTGTAATGTTACAAAT
ATCCCTGTATATGGTAGTAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MEQYVVKGGVPLRGKVSIGGAKNAALGILAAAIMTDDTVTIENVPNVRDTRVLLQAIEGIGAKVKYVYNNSVQINGGSIC
DTNVEYDYIRKIRASYYLLGALLGKYNEAHVALPGGCNIGSRPIDQHIKGFKALGADVDIDCGVVHAKAEKLTGAHVYFD
VVTVGATINLMMASCMAEGDTILENAAKEPHIVDVANFLNSMGANIKGAGTDVIRIKGVKRLHGCTYSIIPDQIEAGTFM
MAAAATHGDVVIQDIIPKHMESISAKLIEMGCRIEEGDDSLRVIAEGCTLRSTNVKTLPYPGFPTDMQPQISVVLALAEG
SSMVTESIFENRFKYVDELGRMGAKIKVEGNTAYIEGVKSFCGVQLNAPDLRAGAALVIAALAADGISEIDDIEYIQRGY
EDFEGKITNLGGIIKRVDSERELQKFRLKIG

Sequences:

>Translated_431_residues
MEQYVVKGGVPLRGKVSIGGAKNAALGILAAAIMTDDTVTIENVPNVRDTRVLLQAIEGIGAKVKYVYNNSVQINGGSIC
DTNVEYDYIRKIRASYYLLGALLGKYNEAHVALPGGCNIGSRPIDQHIKGFKALGADVDIDCGVVHAKAEKLTGAHVYFD
VVTVGATINLMMASCMAEGDTILENAAKEPHIVDVANFLNSMGANIKGAGTDVIRIKGVKRLHGCTYSIIPDQIEAGTFM
MAAAATHGDVVIQDIIPKHMESISAKLIEMGCRIEEGDDSLRVIAEGCTLRSTNVKTLPYPGFPTDMQPQISVVLALAEG
SSMVTESIFENRFKYVDELGRMGAKIKVEGNTAYIEGVKSFCGVQLNAPDLRAGAALVIAALAADGISEIDDIEYIQRGY
EDFEGKITNLGGIIKRVDSERELQKFRLKIG
>Mature_431_residues
MEQYVVKGGVPLRGKVSIGGAKNAALGILAAAIMTDDTVTIENVPNVRDTRVLLQAIEGIGAKVKYVYNNSVQINGGSIC
DTNVEYDYIRKIRASYYLLGALLGKYNEAHVALPGGCNIGSRPIDQHIKGFKALGADVDIDCGVVHAKAEKLTGAHVYFD
VVTVGATINLMMASCMAEGDTILENAAKEPHIVDVANFLNSMGANIKGAGTDVIRIKGVKRLHGCTYSIIPDQIEAGTFM
MAAAATHGDVVIQDIIPKHMESISAKLIEMGCRIEEGDDSLRVIAEGCTLRSTNVKTLPYPGFPTDMQPQISVVLALAEG
SSMVTESIFENRFKYVDELGRMGAKIKVEGNTAYIEGVKSFCGVQLNAPDLRAGAALVIAALAADGISEIDDIEYIQRGY
EDFEGKITNLGGIIKRVDSERELQKFRLKIG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=44.6555819477435, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46231; Mature: 46231

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYVVKGGVPLRGKVSIGGAKNAALGILAAAIMTDDTVTIENVPNVRDTRVLLQAIEGI
CCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCC
GAKVKYVYNNSVQINGGSICDTNVEYDYIRKIRASYYLLGALLGKYNEAHVALPGGCNIG
CCEEEEEECCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
SRPIDQHIKGFKALGADVDIDCGVVHAKAEKLTGAHVYFDVVTVGATINLMMASCMAEGD
CCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCCC
TILENAAKEPHIVDVANFLNSMGANIKGAGTDVIRIKGVKRLHGCTYSIIPDQIEAGTFM
HHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCCCCEEE
MAAAATHGDVVIQDIIPKHMESISAKLIEMGCRIEEGDDSLRVIAEGCTLRSTNVKTLPY
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCEEECCCCEECCC
PGFPTDMQPQISVVLALAEGSSMVTESIFENRFKYVDELGRMGAKIKVEGNTAYIEGVKS
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
FCGVQLNAPDLRAGAALVIAALAADGISEIDDIEYIQRGYEDFEGKITNLGGIIKRVDSE
HHCEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHCCEEHHHHHHHHHCCCH
RELQKFRLKIG
HHHHHHHHCCC
>Mature Secondary Structure
MEQYVVKGGVPLRGKVSIGGAKNAALGILAAAIMTDDTVTIENVPNVRDTRVLLQAIEGI
CCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCC
GAKVKYVYNNSVQINGGSICDTNVEYDYIRKIRASYYLLGALLGKYNEAHVALPGGCNIG
CCEEEEEECCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
SRPIDQHIKGFKALGADVDIDCGVVHAKAEKLTGAHVYFDVVTVGATINLMMASCMAEGD
CCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCCC
TILENAAKEPHIVDVANFLNSMGANIKGAGTDVIRIKGVKRLHGCTYSIIPDQIEAGTFM
HHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCCCCEEE
MAAAATHGDVVIQDIIPKHMESISAKLIEMGCRIEEGDDSLRVIAEGCTLRSTNVKTLPY
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCEEECCCCEECCC
PGFPTDMQPQISVVLALAEGSSMVTESIFENRFKYVDELGRMGAKIKVEGNTAYIEGVKS
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
FCGVQLNAPDLRAGAALVIAALAADGISEIDDIEYIQRGYEDFEGKITNLGGIIKRVDSE
HHCEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHCCEEHHHHHHHHHCCCH
RELQKFRLKIG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]